#ACMSD - Twitter Hashtag

Metallobiochemistry lab at UTSA @FeRadLab

over 1 year ago

Excited to share our new publication in JBC on the enol/keto tautomerization of oxaloacetate by ACMS decarboxylase (doi: 10.1016/j.jbc.2024.107878)! This finding highlights the need for further biological testing. #ACMSD #enzymology #Oxaloacetate #metabolism

UTSAChemistry @UTSAChemistry

over 1 year ago

Congratulations to UTSA Chemistry’s Yu Yung, Ian Davis, and Dr. Aimin Liu on their published article in the Journal of Biological Chemistry about “α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto...” Be sure to check it out! https://t.co/HVg75H9HLc

UTSAChemistry's tweet photo. Congratulations to UTSA Chemistry’s Yu Yung, Ian Davis, and Dr. Aimin Liu on their published article in the Journal of Biological Chemistry about “α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto...” Be sure to check it out! https://t.co/HVg75H9HLc https://t.co/qxjjYNEmEB

0

2

0

328

1

3

0

157

Rene Sugar @renesugar

about 2 years ago

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation #ACMSD #rs2121337 #neopterin #MECFS #LongCovid https://t.co/gXAjH0CqQV

1

11

1

6

0

Biomedical Journal @BiomedJ

over 3 years ago

Genetic Markers for #Autism, Hiding in Plain Sight ~ 80% of autism is inherited, but causative genes are hard to identify. Researchers identified the #ACMSD gene as being associated with non-verbal types of #ASD. https://t.co/Pk2xikBhEd

0

2

0

Norwegian PURE-3® @npure3

over 6 years ago

@foundmyfitness "Pharmacological treatments are also being developed to boost NAD+ metabolism by stimulating NAMPT, inhibiting ACMSD & inhibiting NAD+-consuming enzymes." https://t.co/7m7cRwHgvT #Omega3 may stimulate #NAMPT, #PGC1a, #Sirtuins, downregulate #ACMSD & modulate NAD+ recycling via

npure3's tweet photo. @foundmyfitness "Pharmacological treatments are also being developed to boost NAD+ metabolism by stimulating NAMPT, inhibiting ACMSD & inhibiting NAD+-consuming enzymes."
https://t.co/7m7cRwHgvT
#Omega3 may stimulate #NAMPT, #PGC1a, #Sirtuins, downregulate #ACMSD & modulate NAD+ recycling via https://t.co/bcbHDJLWV9

2

13

9

0

Patrik Brundin MD PhD @BrundinPatrik

over 7 years ago

The kynurenine pathway (aka tryptophan metabolism) is also implicated in #parkinsons disease, with #quinolinic acid being a neurotoxin and pro-inflammatory agent. @VAInstitute #ACMSD

Nature Reviews Drug Discovery @NatRevDrugDisc

over 7 years ago

Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond - a new review https://t.co/1ulnCjAgTB

NatRevDrugDisc's tweet photo. Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond - a new review https://t.co/1ulnCjAgTB https://t.co/SmjhKcOCSB

0

23

10

2

0

3

0

2

0

Mirella Meyer-Ficca @Mirella_MeyerFi

over 7 years ago

@gangulyteena @kadzuis @nature @mep_unil There is a new mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content: https://t.co/lQSxo9HfN2

0

4

5

0

Mirella Meyer-Ficca @Mirella_MeyerFi

over 7 years ago

There also is a mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content now! https://t.co/lQSxo9HfN2

Nature Metabolism

@NatMetabolism

over 7 years ago

@Auwerx_Lab identifies an endogenous pathway to boost #NAD+ levels in worms and mice by inhibiting the enzyme #ACMSD. Boosting #NAD+ levels via #ACMSD inhibition ameliorates #NAFLD and #AKI. #NatMetabPicks https://t.co/9QwZmbYavt

0

20

10

1

0

2

0

Mirella Meyer-Ficca @Mirella_MeyerFi

over 7 years ago

@researchonaging @nature There is a mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content now! https://t.co/lQSxo9HfN2

0

1

0

Mirella Meyer-Ficca @Mirella_MeyerFi

over 7 years ago

#ACMSD is important for dietary #niacin requirements, #NAD tissue content and aging. ANDY, the new #ACMSD #mouse can be used to modulate tissue #NAD content and should be great tool for #NADresearch in #aging, #health, #cancer, #DNArepair and #Epigenetics. https://t.co/lQSxo9HfN2

0

1

0

Norwegian PURE-3® @npure3

over 7 years ago

Another potential #Omega3 #AntiAging mechanism: https://t.co/8hMWGi9JIm #ACMSD #NAD+ #SIRT1 #Mitochondria https://t.co/560rEi5Ygr

0

19

12

0

Nature Metabolism

@NatMetabolism

over 7 years ago

@Auwerx_Lab identifies an endogenous pathway to boost #NAD+ levels in worms and mice by inhibiting the enzyme #ACMSD. Boosting #NAD+ levels via #ACMSD inhibition ameliorates #NAFLD and #AKI. #NatMetabPicks https://t.co/9QwZmbYavt

0

20

10

1

0