Top Tweets for #AHARME
👆 Final Wrap-Up of the 4 #RCT dedicated to #HF presented at #AHA21
#AHARME
@JavierdeJuan1 @JJheart_doc @ACCinTouch @escardio @Dr_Manito @SantosGallegoMD @mvaduganathan @SJGreene_md @brendonneuen @nephondemand @HeartOTXHeartMD @DocSavageTJU @TJHeartFellows @DBelardoMD @iamritu
#AHARME
Brief Summary and wrap-up of the 4 #RCT dedicated to #HF presented at #AHA21
@radcliffeCARDIO @AHAScience @AHAMeetings
The most impactful on clinical practice to me would be:
🔥 #EMPULSE 🥇
@ValleAlfonso @ShelleyZieroth @hvanspall
@DrNasrien @DrMarthaGulati @DLBHATTMD
Grateful to present at #AHA21 #QCOR session on tackling global #SexDisparities in #CVD. A few more slides w/ refs
🔗https://t.co/ta3BGn0UA6
🔗https://t.co/5z2QC8gte6
🔗https://t.co/IyOOTE0sR0
🔗https://t.co/Y3wieYVrZa
🔗https://t.co/3EFZIPn4gm
🔗https://t.co/yQJxIpiZwD #AHARME
To wrap-up, a phenomenal talk by @hvanspall on the important topic of global under-representation of women in clinical trials & strategies to improve them
#AHA2021 #QCOR21 @American_Heart @rachkataria @SantosGallegoMD @ersied727 @avolgman @ShrillaB @Drroxmehran @drdargaray
#AHA21 via NodeXL https://t.co/h7EMPmXiao
@ahascience
@ahameetings
@kevin_volpp
@drmarthagulati
@american_heart
@nejm
@botcardiology
@heartnews
@dlbhattmd
@jaccjournals
Top hashtags:
#aha21
#cardiotwitter
#aharme
#empulse
#sglt2i
#heartfailure
#healthtech
#ahafit
#AHA21
💥Please join us 930 EST for featured science on #HF & #CKD, which I’m honoured to co-moderate with THE @EldrinL and THE @AndrewJSauer (who will take your questions on #Twitter). From #SGLT2i to #MRA #SGCstimulator & #AI, we have you covered! #HeartFailure #AHARME
#AHA21 #QCOR21 countdown continues
Check out this 💫 session w/ @rohan_khera @Mark_Huffman et al.
Grateful to present strategies to improve #CVD outcomes in 👩🏽 across the 🌎, from #policy to #research to #care.
Will present some of our work in global health.
#AHARME
@fikkumamoto @DrMarthaGulati @DLBHATTMD @keaglemd @Drroxmehran @JavedButler1 @NMHheartdoc Too much to fit in a single tweet, but we will post more #AHA21 studies today. Looking forward to more late breaking science on #HF or #CKD therapies - #Empagliflozin (@JavedButler1 presenting) #Fineronone #Vericiguat and💫 session on closing 🌎 disparities in CV care. #AHARME
🚨EMPEROR-P 🚨
🗣Subanalysis 👥w/LVEF>50%
🥇Empa⬇️primary endpoint 17% ( p=0.024), mainly driven by ⤵️ in first HF 🏥
🥇 Improvement in QoL and symptoms 🥵🔁😉
#AHA21 #AHARME
@IccResidencia @comiteic @EduardoPerna1 @MkosiborodMD
@kaulcsmc @djc795 @AdriaanVoors Posting my link to the analytic plan (Methods paper) where threshold of 5 is outlined + screen grab of the #AHA21 slide. I did not hear of any protocol deviations, but need to listen to the presentation again. The paper is to be published in Nature Medicine, fyi. #AHARME
@djc795 @mvaduganathan @kaulcsmc My interpretation based on supplement was that
- threshold of 5 = difference in #KCCQE-TSS req’d to establish a win between pairs (not the longitudinal difference from baseline to 90d)
- difference < 5 is a tie
Very reasonable approach!
Thoughts?
#AHA21 #AHARME #Empulse #LBCT
I cheered on @AdriaanVoors & #EMPULSE from the green room (so apologize for quality of slides). Brilliant analysis, and yes #KCCQE results were presented. #Winning #AHA21 #AHARME #SGLT2i #HF
@hswapnil @mvaduganathan, @hvanspall, @djc795
Wasn't improvement in KCCQ‐TSS of ≥5 points from baseline a component of the primary clinical benefit?
Did I miss the result? Was it shown?
🚨EMPULSE🚨
👉🏥initiation EMPA🆚️placebo
👉👥Acute HF👉Stable/up to 90 d
👉33% novo acute HF, 45% DBT, 32% EF>40
👉all cause🪦/HF events/⌛HF events/🔁KCCQ
👉🥇EMPA🥇36%📊clinical benefit
#AHA21 #AHARME
@SoCaCorr @IccResidencia
@EduardoPerna1
@PabloCimbaro @MariaLorenaCo12
❤️🩹 #AHA21 #AHARME
#DREAM_HF a real example of “translational research” failed in reducing 1st EP
But positive signs for subgroups:
📌NYHAII
📌⬆️ hsCRP
@radcliffeCARDIO @hvanspall @ShelleyZieroth @gbiondizoccai @IndolfiCiro @SIC_CARDIOLOGIA @SilCastelletti @DrNasrien @rahatheart1
#AHA21 #AHARME
#DREAM_HF on #MesenchymalPrecursorCells
Did not reduced the Primary #EP
Anyway positive analysis on subgroup (NYHA II & ⬆️hsCRP) tell us that “dream can become true in future”
@radcliffeCARDIO @AHAMeetings @ValleAlfonso @hvanspall @ShelleyZieroth @DrMarthaGulati
👆 🔥 ❤️ #EMPULSE
#AHA21 #AHARME
Another piece of the great puzzle 🧩 of #SGLT2i
#AcuteHF irrespective od #diabetes status
@radcliffeCARDIO @AHAMeetings @HanCardiomd @fikkumamoto @lucreciamburgos @ValleAlfonso @hvanspall @ShelleyZieroth
👆 🔥 ❤️ #EMPULSE
#AHA21 #AHARME
Another piece of the great puzzle 🧩 of #SGLT2i
#AcuteHF irrespective od #diabetes status
@radcliffeCARDIO @AHAMeetings @HanCardiomd @fikkumamoto @lucreciamburgos @ValleAlfonso @hvanspall @ShelleyZieroth
How’s this for a selfie??
#Legends @EldrinL @MinnowWalsh @BiykemB @NMHheartdoc
.. and me!
Could this be real??
Thank you @AHAMeetings @manesh_patelMD @dramitkhera! I’m so grateful for the opportunity to contribute.
#AHA21 #LBCT #HeartFailureLegendsAndMe
#AHARME
As I’m scrolling James’ Twitter feed and spewing coffee out of both nostrils, I saw this one and immediately thought of @hvanspall ‘s critiques of my selfie abilities!😂📸
I’ve not seen any good selfie action from #AHA21 ! What’s up, y’all ?!
#EMPULSE 🏅
#AHA21 #AHARME
Confirm the #SGLT2i benefits in #AHF irrespective od #diabetes status
Another confirmation after #SOLOIST of benefit in this population
@radcliffeCARDIO @ValleAlfonso @ShelleyZieroth @hvanspall @DrMarthaGulati @JJheart_doc @DLBHATTMD @DrNasrien
👆#AHA21 #AHARME
#CHIEF_HF Canagliflozin in #HF confirmed the benefits of #SGLT2i on #QoL on #HF pts irrespective of #diabetes status & of #EF
@ValleAlfonso @radcliffeCARDIO @AHAMeetings
#AHA21 #AHARME
🔥 #CHIEF_HF confirm the important impact of #SGLT2i on #QoL in #HeartFailure across all the #EF spectrum & irrespective of #diabetes status
@radcliffeCARDIO @AHAScience
@ValleAlfonso @hvanspall @ShelleyZieroth @gbiondizoccai @DBelardoMD @DrMarthaGulati @iamritu
⚠️The Canagliflozin Impact on Health Status, Quality of Life and Functional Status in HF #CHIEF-HF #AHA21 #AHARME @radcliffeCARDIO
👉 ⬆️4.3points KCCQ-Total at 12 weeks for canagliflozin vs. placebo (p = 0.016).
👉Results similar for
📌HFrEF and HFpEF
📌patients with /o DM2.
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