Top Tweets for #Bendamustine
π¨ Comparative Efficacy of #Bendamustine vs #FluCy for Lymphodepletion before #CAR_T in NHL π¨
πΉ Background: Lymphodepletion is key for CAR-T expansion. Standard = Flu/Cy, but shortages & toxicities β search for alternatives.
πΉ Study: Retrospective (2018β2023), 265 pts, FDA-approved CAR-Ts in R/R NHL.
πΉ Efficacy:
OS @1y: 71% (Benda) vs 68% (Flu/Cy) π
PFS @1y: 68% vs 60% (NS)
No diff in CRS β‘ or ICANS π§
πΉ Toxicity:
ANC <0.5 only in 29% (Benda) vs 83% (Flu/Cy) π«π©Έ
ALC & ANC nadirs significantly milder with Benda
πΉ Logistics:
Easier single-drug dosing π
Less hospitalization, outpatient-friendly π‘
Practical advantage during Flu shortage
πΉ Multivariable: Infusion year strongest predictor of OS & PFS β reflects practice improvement over time.
πΉ Takeaway: Bendamustine = viable alternative LDC β comparable efficacy, safer hematology profile, operational ease.
π Ref: ASTCT J 2025 https://t.co/XOCfiOLQXg
π Credits for sharing: Dr Mohammed Alshahrani
#Lymphoma #CART #HemOnc #ASH25 #ASTCT #CellTherapy
Pola-R-GemOx cut mortality risk by 40% vs. R-GemOx in relapsed/refractory #DLBCL (POLARGO, EHA 2025). Median OS: 19.5 vs 12.5 months. @RutgersCancerβs Dr. Matthew Matasar: βA new tool for clinicians avoiding #Bendamustine-related limits.β https://t.co/aouRferJN6 #EHA25
Dr. Kumar and team explored the role of bendamustine as palliative chemotherapy in patients with metastatic, recurrent, or relapsed HNSCC. Read more: https://t.co/40bpRiq2wk
#CRST #CancerResearch #oncology #MedTwitter #bendamustine
Study looks at #PolatuzumabRituximab with or without #bendamustine in patients with #RelapsedLymphoma. #LBCL #ASH22 #MiamiCancerInstituteResearch
Bendamustine in combination with ifosfamide, etoposide, and vinorelbine (VIBE) is an effective salvage regimen for heavily pre-treated patients with relapsed or refractory Hodgkin lymphoma: a single-center experience
https://t.co/JXq3oZWCtg
Gaurav Prakash
#Salvage #Bendamustine
Frontline treatment with #ibrutinib, #bendamustine, and #rituximab showed a prolongation in progression-free survival along with a good response rate in older patients with mantle cell #lymphoma. #MCL #lymsm
https://t.co/86TIleLD2V
In a #retrospective study, @AndrewLimper and colleagues found a 1.7% cumulative incidence of #pneumocystis #pneumonia (#PJP) in patients receiving #bendamustine-based therapy. https://t.co/3AyO3Wo5PZ
Also in the August issue: SEQUOIA - #Zanubrutinib versus #bendamustine and #rituximab in untreated chronic lymphocytic #leukaemia and small lymphocytic #lymphoma: a randomised, controlled, phase 3 trial https://t.co/Hx1ehJv6ak
#Ibrutinib plus #Bendamustine and #Rituximab in Untreated #MantleCellLymphoma:
Exciting new chemotherapeutic combination!π
https://t.co/liz3BnUKWd
@MJerkeman
Online first: SEQUOIA - #Zanubrutinib versus #bendamustine and #rituximab in untreated chronic lymphocytic #leukaemia and small lymphocytic #lymphoma: a randomised, controlled, phase 3 trial https://t.co/Hx1ehJMHyU
This study evaluated the outcomes of patients with refractory/relapsed Hodgkin #lymphoma treated with a #bendamustine-based regimen in combination with ifosfamide, etoposide,...
Blood Res 2021; 56(3)πhttps://t.co/52lSZVByB9
@Charanpreet_14 @Aditya_PGI @Lad_Deepesh @DrPMPGI
How useful is a #carfilzomib, #bendamustine, and #dexamethasone treatment combination for hard-to-treat multiple myeloma?
https://t.co/TxTGDHX0jZ
Paraneoplastic acute fibrinous and organizing #pneumonia from #lymphoma completely responding to #bendamustineβrituximab https://t.co/H2hdQ4cOGt in #RespirologyCaseReports
VIDEO: Post-transplant #Bendamustine for #GvHD prophylaxis in #RefractoryAcuteLeukemia w/ Ivan Moiseev of @SPbGMUofficial: https://t.co/IZCvRIrg77
#EMBT20Virtual @TheEBMT #Leukemia @OncoAlert #OncoAlert #HemOnc #Leusm
#API ONCOLOGY(COMPLEX)
This company have super bright future. Revenues to flow soon.
#SHIVALIKRASAYAN
ONCOLOGY
#Capecitabine
#azacitidine
#Busulfan
#Temozolomide
#Bendamustine-HCI
#Bortezomib
#Gefitnib
#Imanitab
#Erlotinib
#Pazopanib
#Lelanidomide
#Pomalidomide
There is a small #API company in India which will create massive wealth for shareholders in next 5 years.
But Yes, you have to sit tight on your ass with lot of patience as price swings badly on both sides
It will sell all of its production from day 1 of plant commencement.
I have had some cases of cold agglutinin disease that have been challenging to treat. Rituximab+ Bendamustine has a great response rate (78%). @Bloodman @BloodJournal #hematology #FOAMed #meded #CAD #bendamustine @Svematologist
https://t.co/9v6lTSZK2f
#OncoAlert Progressive multifocal leukoencephalopathy in patients with follicular #lymphoma treated with #bendamustine plus rituximab followed by rituximab maintenance #lymsm https://t.co/jFkpHjjvUn
Olszewski et al
Interesting population based data from the US suggesting equivalent survival outcomes for #rituximab monotherapy vs #bendamustine-rituximab in marginal zone lymphoma
#ASH19 #lymsm
Para iniciar la quimioterapia de Romina Riera, se necesita urgentemente BENDAMUSTINE. Por favor RTππ½ @fundacionjesed @FLaPastilla @DONANDOTRATAMI @DonandoMedicin1 @medicamentosff @turecipeonline @Farmabien @fundatiacruz π #todosxromi #ServicioPublico #URGENTE #Bendamustine
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