Top Tweets for #CETPi
@JohnKastelein @DrDerekConnolly @TIMIStudyGroup @ProfKausikRay Let’s see with #Obicetrapib as a #CETPi what will be the magnitude of benefits on #MACE ☀️
In the BROADWAY trial involving patients at high cardiovascular risk, the cholesteryl ester transfer protein inhibitor obicetrapib reduced low-density lipoprotein cholesterol levels by 29.9% at 84 days. Full trial results and Research Summary: https://t.co/YHt2m5JYeU

Recent advances in immunotherapy targeting #CETPi for #atherosclerosis prevention https://t.co/7y9DLJ0bRb
Last field in which #CETPi may play a role : sepsis. Interesting session by J Kastelein at #EASCongress2023




#EASCongress2023 nice session about #CETPi with @JohnKastelein explaining the development on these agents and CV benefits mainly linked to #ApoB decrease.

Our Chief Scientific Officer, @johnkastelein, joined @AlainBouchard for a @myheartnet podcast exploring the benefits of combination therapy for LDL lowering in #ASCVD. Learn how a new mechanism, #CETPi, is showing promise across multiple trials. https://t.co/l9ZNnKfV1H
Compare these figures to the latest data from our Phase 2b trials evaluating our #CETPi on top of high-intensity statin therapy. ROSE2 saw a median 59% ⬇️ in LDL-c with the obicetrapib + ezetimibe combination, plus favorable safety & tolerability. https://t.co/FpqPhKN4ei

This American #HeartMonth, we continue development of our #CETPi, obicetrapib -- with the goal of delivering a simple, oral and potent LDL-lowering treatment for the many millions of patients not achieving their LDL goals. https://t.co/JTYmPCMfui

The association between #Alzheimers & #ApoE4 is a key reason we’re studying our #CETPi, obicetrapib, in Alzheimer’s patients. We believe increasing functional HDL with CETPi could promote healthier #cholesterol metabolism in the brain, potentially treating Alzheimer’s disease.
ApoE4 is also associated with increased ASCVD risk. If one knows their apoE genotype earlier in life than later, there are likely lifestyle & other ways to reduce future cognitive, AD & ASCVD risk

Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease | European Heart Journal important follow data showing benefit and safety of lowering #LDL with #CETPi @ProfSNicholls @JohnKastelein https://t.co/FCp8u93Q94
That was a stupid, unrealistic dream $MRK had for its #CETPi. Could’ve saved billions by skipping the latest trial.
Just wait for $ESPR https://t.co/4AKR8LjSk5
Rx Reading: $MRK shelves its CETP dreams; $ARDX sees success with IBS drug; California passes drug pricing law https://t.co/g6vfkJqEW8
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