Top Tweets for #Cosmic312
@TumorBoardTues @BonumCe @rachnatshroff @DJPinato @MPishvaian @GABOUALFA @marinabaretti @marklewismd @US_FDA @DrJNaidoo @cappelliMD @JulieBrahmer @DanengLi @llovet_m @LorenzaRimassa 14/ #TumorBoardTuesday
#COSMIC312 - cabo + atezo vs sorafenib
⬆️ in PFS but not OS
⚠️ G3/4 TRAEs: 64% vs 46%
⚠️ Discont due to TRAEs: 14% vs 8%
⚠️No excess of serious bleeding events in cabo arm despite no requirement for endoscopy prior to enrollment
⚠️ Common G3/4 TRAEs 👇
#ILCA2022, Systemic therapy guidance talk ongoing with Tim Meyer & Robin Kate Kelley.
Important clinical practice questions to address with recent/upcoming results from Phase 3 trials: #COSMIC312, #HIMALAYA, #LEAP002, #RATIONALE301 & Camrelizumab+rivoceranib in 1L #HCC #MedEd
#COSMIC312 phase 3 trial of cabozantinb + atezolizumab vs sorafenib in first-line #HCC presented by #KatieKelley at #ESMOVirtualPlenary #ESMOasiaweek21. Improved #PFS, but not yet #OS. Also data on #cabozantinb single-agent @myESMO
#Cabometyx の適応拡大が頓挫したことで、#Exelixis 社は新たな成長戦略を模索し始めた。挫折したのは #Cosmic312 のデータで、肝がんの前治療で生存率の改善が見られなかった。競合他社の脅威が高まるなか、他のがん種で成果を上げる必要がある。
https://t.co/878P2MIqRK
#エバリュエート
Another video from #ESMO19 about the #COSMIC312 trial of #cabozantinib plus #atezolizumab for advanced #HCC
@myESMO #CongressReport https://t.co/pTv1hHpIfn
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