#DNMT3b - Twitter Hashtag

6 months ago

The CBFA2T3-GLIS2 fusion reshapes chromatin & #DNAmethylation landscapes in #PediatricAML via DNMT3B-driven enhancer activation, promoting #oncogenic signaling & #chemoresistance, while #DNMT3B inhibition enhances sensitivity to #BCL2-targeted therapy. Read: https://t.co/MfWiAaBYvS

GenesNDiseases's tweet photo. The CBFA2T3-GLIS2 fusion reshapes chromatin & #DNAmethylation landscapes in #PediatricAML via DNMT3B-driven enhancer activation, promoting #oncogenic signaling & #chemoresistance, while #DNMT3B inhibition enhances sensitivity to #BCL2-targeted therapy.
Read: https://t.co/MfWiAaBYvS

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Acta Pharmaceutica Sinica B @ActaPharmSinB

over 1 year ago

Video Abstract📺#P2Y14R activation facilitates #liver #regeneration via #CREB/#DNMT3b/#Dact-2/β-#Catenin signals in acute #liver #failure. From Dr. Hu @ChinaPharmaceuticalUniversity; https://t.co/QQiVWP6aAO.

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Acta Pharmaceutica Sinica B @ActaPharmSinB

over 1 year ago

Article✍️#P2Y14R activation facilitates #liver #regeneration via #CREB/#DNMT3b/#Dact-2/β-#Catenin signals in acute #liver #failure. From Dr. Hu @ChinaPharmaceuticalUniversity; @ELSpharma. https://t.co/QQiVWP6aAO.

ActaPharmSinB's tweet photo. Article✍️#P2Y14R activation facilitates #liver #regeneration via #CREB/#DNMT3b/#Dact-2/β-#Catenin signals in acute #liver #failure. From Dr. Hu @ChinaPharmaceuticalUniversity; @ELSpharma.
https://t.co/QQiVWP6aAO. https://t.co/wEtom6t9gT

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Manel Esteller

@ManelEsteller

over 3 years ago

Yesterday #rarediseaseday. Among syndromes we studied, #Rett + #Sotos+ #MECP2 duplication + #DNMT3B #ICF + Ohdo + Cornelia de Lange + DICER1 predisposition + Beckwith-Wiedemann #BWS + Werner + Hutchinson-Gilford Progeria + Multisystem Inflammatory Syndrome in Children #MISC

ManelEsteller's tweet photo. Yesterday #rarediseaseday. Among syndromes we studied, #Rett + #Sotos+ #MECP2 duplication + #DNMT3B #ICF + Ohdo + Cornelia de Lange + DICER1 predisposition + Beckwith-Wiedemann #BWS + Werner + Hutchinson-Gilford Progeria + Multisystem Inflammatory Syndrome in Children #MISC https://t.co/phDjHx2mmA

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Randompile @RandompileVideo

almost 4 years ago

Preprint on #bioRxiv: https://t.co/fWgLNaV7Qc #haiku #gpt3 #dalle2 #lncrna #dnmt3b

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Chirag Nepal @ChiragNepal

over 4 years ago

Our new work describing the mechanism of activation of alternative promoter in #LiverCancer #HCC. #Genereguation #AlternativePromoter #SETD2 #H3K36me3 #DNMT3B #TET1 #CGdinucleotide @UCPHAndersenLab @LLUHealth https://t.co/hXrlmGNaK2 1/15

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Iwase Laboratory @Iwase_Lab

about 5 years ago

We IDed 4 NDDs with ectopic germline expression in the brain #ICF1 #Kleefstra #MDS #MRXSCJ. Mutations in genes #DNMT3B #G9A #GLP #MECP2 #KDM5C may lead to germline gene derepression & a severe identity crisis of brain cells, interfering with normal development.

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Cancer Research @CR_AACR

over 6 years ago

So et al. find DNA methyltransferase 3B (#DNMT3B) to be a key factor in #MetastaticCancer as it alters multiple #SignalingPathways. Their work suggests targeting DNMT3B induction as new option for treating metastatic disease. @NCIResearchCtr https://t.co/GcxZbHPVgQ

CR_AACR's tweet photo. So et al. find DNA methyltransferase 3B (#DNMT3B) to be a key factor in #MetastaticCancer as it alters multiple #SignalingPathways. Their work suggests targeting DNMT3B induction as new option for treating metastatic disease. @NCIResearchCtr https://t.co/GcxZbHPVgQ https://t.co/nKm6Ab5WtB

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MedChemExpress

@MedChemExpress

over 6 years ago

DS-437 is a dual #PRMT5/7 inhibitor (IC50s of PRMT5/7=6 μM). DS-437 is an S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5. DS-437 also inhibits #DNMT3A and #DNMT3B. DS-437 inhibits the methylation of #FOXP3.#Lymphoma.#drugdiscovery.https://t.co/myuxOTgIcV

MedChemExpress's tweet photo. DS-437 is a dual #PRMT5/7 inhibitor (IC50s of PRMT5/7=6 μM). DS-437 is an S-adenosylmethionine (SAM)-competitive inhibitor of PRMT5. DS-437 also inhibits #DNMT3A and #DNMT3B. DS-437 inhibits the methylation of #FOXP3.#Lymphoma.#drugdiscovery.https://t.co/myuxOTgIcV https://t.co/c61q0gLvEq

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