Top Tweets for #ERSTRESS
This study demonstrates that CHOP deficiency intensifies inflammation, epithelial apoptosis, and injury by suppressing ER stress, pointing to CHOP as a therapeutic axis.
Read: https://t.co/1vTA74NxbK
#currentmedicalscience #Urology #CHOP #ERStress #Apoptosis

#EditorsChoice
Read now ➡️ "Selenoprotein N and SEPN1-Related Myopathies: Mechanisms, Models, and Therapeutic Perspectives" by Martina Lanza, et al.
The review 👉 https://t.co/XyW5PJPyxk
The list 👉 https://t.co/rb7fhtmaQC
#Myopathy #SelenoproteinN #ERStress #RareDisease

Can dual-targeting #UFMylation inhibitors defeat #Glioblastoma?
Targeting the DDRGK1–UFL1 pathway with osimertinib or CP-24 suppresses UFMylation and ER-phagy, induces #ERstress and promotes antitumor M1 macrophage polarization. @Tsinghua_Uni
#STTT #OpenAccess: https://t.co/JdmLSeXo6U
Could targeting #necroptosis improve disease treatment?
This review reveals how #ERstress regulates necroptosis, highlighting promising therapeutic targets for inflammation- and cell death-related disorders.
#OpenAccess #GenesAndDiseases: https://t.co/hGbIhQ6Pec

Happy to share our @trendscancer commentary on a great @Nature paper showing that #ERstress in #cancer cells can also support immune evasion. Kudos to @luciaborriell! @FoxChaseCancer #threeCs Free at https://t.co/saeyIAzAuU

🧪The work from @GifuUniv_PR by Prof. Kentaro Oh-hashi and his team is featured in IJP!
Article 👉: https://t.co/fK6AAwG3oc
💡How does #TXNDC11 shape #ERStress responses by balancing #ERAD and #ERphagy in neuronal cells?
#cellbiology #neurobiology

#HutchinsonGilfordProgeriaSyndrome
Intriguing 🐭data showing that Progerin-induced #ERStress #UnfoledProteinResponse in Aorta is NOT EC-origin
Evidence from
1⃣Cdh5-tTA::tetop-LA G608G 🐭
3.5 or 6 mo, endothelial progerin transgene, primary lung & heart EC & aortic tissue
2⃣Lmna G609G knockin 🐭
3.5 mo, re-analysis of scRNAseq Aorta
Love to see more in situ aortic endothelial data
@Selma_OsMyers @LSAjournal 2025
https://t.co/u11vu06fiB

🩸Uterine myomas crank up ER stress & oxidative damage: GRP78/CHOP sky-high (AUC 0.95–0.97)! 🔥 #UterineFibroids #ERStress #OxidativeStress
🏠Affiliation:@cumunivkurumsal ,@tcktu1955 ,@cumunivkurumsal
📚Read more:https://t.co/xTNcdq8TnU

Hello all, here's my final work as a postdoc with @UMich Go Blue!!! 💙💛
#betacells #ERAD #ERstress #proinsulin #proteinfolding #insulin #diabetes
New insights into islet ER stress responses, proinsulin biosynthesis, ERAD and ERD1 using β-cell-specific Hrd1-KO mice & rodent (and human islet) β-cells treated acutely with HRD1 inhibitor. https://t.co/3ph5T8RlUd @jclinicalinvest

Ever wonder why people with #ME/CFS or long #COVID feel exhausted for days after mild activity? This review discusses mitochondrial dysfunction as a potential shared mechanism and therapeutic target.
Abu Mohammad Syed, et al.
➡️ https://t.co/2eXxC2zwQA
#mitochondria #ERstress

#VascularCalcification Mechanobiology
#HydrostaticPressure 120 mmHg 7 d➡️
⏫#Piezo1➡️ (⏫ #ERStress GPR78 CHOP➡️)
⏫ #SmoothMuscleCell Calcification (~20% level by 4 mM Pi)
#BBAMolBasisDis 2025
https://t.co/DnSIcfixTY

Many peptides are known for direct signaling, but a profound insight reveals some subtly modulate the Unfolded Protein Response (UPR). This isn't just about protein folding; it's a critical cellular stress adaptation system. #PeptideScience #ERStress
We developed an ex vivo method to assess IRE1α-dependent RNA cleavage from mouse tissues.
🔗 https://t.co/RKsTjhZp1j
Grateful to Prof. Han-Jung Chae, my co-authors & my wife—my better half—for her endless support 💖
#IRE1α #ERstress #RIDD #RNAdecay #BioProtocol

Spinal NTRK1→IGF2→ER stress fuels chronic #Postsurgical #Pain 🤯 🔥SMIR rats: block NTRK1 or silence IGF2=pain relief🩹🧬A non‑opioid precision #Analgesia target 🚀 🔬 @Biomed_MDPI @MDPIOpenAccess #CPSP #NTRK1 #IGF2 #ERstress #Pain
https://t.co/RXhzARRP6N
Spinal NTRK1→IGF2→ER stress fuels chronic #Postsurgical #Pain 🤯 🔥SMIR rats: block NTRK1 or silence IGF2=pain relief🩹🧬A non‑opioid precision #Analgesia target 🚀 🔬 @Biomed_MDPI @MDPIOpenAccess #CPSP #NTRK1 #IGF2 #ERstress #Pain
https://t.co/RXhzARRP6N
Aging triggers mitochondrial, endoplasmic reticulum, and metabolic stress responses in the heart
📖 Read: https://t.co/IUv0DRFeCE
#CardiovascularAging #Mitochondria #ERStress #HeartHealth #AgingResearch

REVIEW🚨
Rodriguez, Cubillos-Ruiz @JCubRuiz &Co discuss how the #ERstress response affects intratumoural immune cells & highlight the potential of #UPR-targeted interventions to improve cancer outcomes.
@MoffittResearch @WeillCornell
👀⬇️
https://t.co/2c6CXLzH00
🔓#OpenAccess: Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Abu Mohammad Syed, et al.
🖱️https://t.co/MX3zNkQgxy
#mitochondria #ERstress

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