Trends in Cancer

Trends in Cancer is a leading reviews journal covering advances in cancer research and oncology published by Cell Press. Tweets by Editor Danielle Loughlin.

[Trends in Cancer @trendscancer]

Last chance to share your latest cancer research!
Submit a late-breaking abstract for @CellPressEvents #CSHallmarks2026 and present your work alongside leaders in the field in Sitges, Spain next month.
Don't miss out, submit here: https://t.co/414O8QsOqZ

[Trends in Cancer @trendscancer]

Heading to @CellPressEvents #CSHallmarks2026 next month?
After a day of groundbreaking science, unwind at El Vivero Beach Club. Enjoy the Meet the Speakers dinner, make new connections, and be captivated by a live flamenco performance 💃
Register: https://t.co/LcxDn1I9cO

[Eric Topol @EricTopol]

Engineering T cells for immunotherapy vs cancer had already had marked success in certain types. But there's a next generation in the hopper, as reviewed today @Cancer_Cell, that ought to help take the field much further into solid tumors
https://t.co/FJd3qn4KuM

[Trends in Cancer @trendscancer]

How can AI and emerging technologies decode systemic factors in cancer?

Find out @CellPressEvents #CSHallmarks2026 from experts, including: Theodore Alexandrov (@UCSanDiego), @IamLinghua (@UTMDAnderson), Eytan Ruppin (@theNCI) & @Kunhsingyu (@harvardmed)

https://t.co/S4XV8wm1aE

[Upasana DasAdhikari @UpasanaDA]

Thrilled to share our new paper in Science! 🎉
We uncover how dietary fat–driven ceramide synthesis activates YAP-dependent regenerative programs to promote colorectal cancer metastasis, independently of primary tumor growth.congrats @SwagataGoswam16 https://t.co/5fy0prv40Q

[Trends in Cancer @trendscancer]

Looking forward to our session on "Systems oncology" @CellPressEvents Hallmarks of cancer, with speakers @leeat_keren, Zemin Zhang @CQMU1956, & @TiroshLab.
Register today and secure your place: https://t.co/2m3E3lIvGY
#CSHallmarks2026

[Eric Topol @EricTopol]

Pulling out all the stops vs pancreatic cancer.
The recent FDA-approved, celebrated drug daraxonrasib, increased median survival by 6.5 months @RevMedicines
That's a positive step but clearly not enough. This new @Cancer_Cell paper lays out a path for more.
https://t.co/i3Kb8fEDzm

[Cancer Cell @Cancer_Cell]

EGFR-targeting ADCs: From oncogene addiction to antigen-guided drug delivery https://t.co/GgYGolGIFk

[Trends in Cancer @trendscancer]

We're excited to hear from invited speakers @michelle_monje, Frank Winkler (@HeidelbergU), Timonthy Wang (@ColumbiaCancer) & @moranamit2 in our session on #CancerNeuroscience @CellPressEvents #CSHallmarks2026, Nov 1–3, Sitges, Spain
Check out the program: https://t.co/ndphbyDR5W

[Yakup Ergün @dr_yakupergun]

CDK4/6 inhibitors arrest the cell cycle by activating Rb. But the authors provide compelling evidence that the story does not end there.

A new Nature study shows that hypophosphorylated Rb unexpectedly enhances ER-mediated transcription. Rb relocates to enhancer regions and reactivates proliferative ER-target genes, including CCND1.

So, paradoxically, CDK4/6 inhibition leads to:

E2F ↓ → proliferation ↓
but at the same time
Rb → ER transcription ↑ → proliferative counter-response ↑

Endocrine therapy shuts down this second pathway. This finding reveals a new mechanism that may help explain the strong biological rationale for combining CDK4/6 inhibition with endocrine therapy, while also pointing to a potential mechanism of resistance.

https://t.co/IUDH16yDiS

[Trends in Cancer @trendscancer]

⏰Early bird registration for Hallmarks of cancer closes today!

Join us in Sitges, Spain for inspiring science, lively discussions and the breathtaking beauty of the Mediterranean!

Register now: https://t.co/Q3SpEJsr9Q
@CellPressEvents #CSHallmarks2026

[Dvir Aran @dvir_a]

Our paper is out in @Cancer_Cell!
We started this project almost 5 years ago with the idea that to understand why some cancer patients respond to immunotherapy and others do not, we may need to look beyond the tumor before treatment. Immunotherapy is not just a test of a pre-existing state; it is a perturbation. It changes the tumor immune microenvironment.
So the question became: can the direction of that change explain response?
https://t.co/wHmh8tQ3Xx

[Anirban Maitra @Aiims1742]

New paper from @BiffiGiulia in @NatureCellBio comparing fibroblast diversity and epithelial–stromal interactions between #pancreatitis and #PancreaticCancer using a plethora of sample types across species. Congratulations Giulia!
https://t.co/t7ndKcsar6

[Bruno Lopes Bastos @BLopesBastos]

#RareCancers face massive bottlenecks: limited patient material, few models, and slow screening pipelines. In our new Forum article in @TrendsCancer, we propose a "Zebrafish-First Triage Strategy" to rapidly model, test, and prioritize targets. https://t.co/tH1C2YirSY

[Trends in Cancer @trendscancer]

Hear Timothy Wang @columbiacancer discuss how nerve-cancer connections orchestrate the tumor microenvironment in gastrointestinal tumors @CellPressEvents #CSHallmarks2026
Early bird registration closes September 4!
https://t.co/YvBBWrl5JI

[Anirban Maitra @Aiims1742]

Final version of @NeehaZaidi paper on Mutant KRAS Vaccine for #PancreaticCancer interception in high risk cohorts out in @CD_AACR.
https://t.co/6GTEnTTTDY
Notable data is detection of KRAS antigen targeted T cells 1 year post vaccine - annual boosters as a prevention strategy?

[Dr. Anthony Letai @NCIDirector]

Pancreatic cancer is notoriously hard to treat, but we are making progress. Recent @theNCI -funded work that sheds light on mechanisms behind #daraxonrasib resistance and could help clinicians choose treatment combos that outsmart pancreatic tumors. https://t.co/mkz4CxaeBs

[Trends in Cancer @trendscancer]

📢Call for late-breaking abstracts!
Have new or groundbreaking findings to share? #CSHallmarks26 is now accepting late-breaking abstract submissions. Submit by October 16 and help shape the future of cancer research.
👉https://t.co/UYRgv5MPPA @CellPressEvents

[Trends in Cancer @trendscancer]

Invited speaker Itay Tirosh @TiroshLab @WeizmannScience will discuss cancer cell states and their spatial organization @CellPressEvents #CSHallmarks2026 in Sitges, Spain, Nov 1–3, 2026.
Register here for a chance to join him: https://t.co/U6Ko5yKkSu

[Cell @CellCellPress]

Now online! Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer https://t.co/pjmggGfkZj