Top Tweets for #FIRSTABC
@LeilaJTF Thank you so much for inviting me to talk about #firstabc trial and the importance of doing a pilot #rct before the main trial. Really enjoyed it! Thanks to the excellent team that supported me @ICNARC @KathyRowan101 @PaulMouncey @DavidHarrison80 @pus27 @lyvonnetume @rgfeltbower
Over years #pccssg has fine tuned the art of the pragmatic #rct in PICU - @SANDWICHTrialUK #firstabc then @OxyPicu all delivering blockbuster results capable of changing clinical care. Thanks @NIHRresearch for funding and @PICSociety for support
.@PICSociety @pic_pram @pus27 @lyvonnetume @ICNARC @PaulMouncey @DavidHarrison80 et al's #FIRSTABC trials (#HFNC v #CPAP) Step Up/Step down were published and presented in @CritCareReviews meeting.
https://t.co/WU1amilnbO
https://t.co/Z58mysVDCI
#PedsICU
What are ur take aways?
@GreatOrmondSt @OsamaHosheh No points for guessing that the article of the month goes to #FIRSTABC Step-up trial
https://t.co/qKPGeOgK54
@pic_pram @pus27 @ICNARC @lyvonnetume et al.
@JAMA_current
Also included few (adult)ICU trials from @CritCareReviews #CCR22 e.g. #CLASSIC #LOVIT #PREPAREII etc.
#PedsICU
Link to study protocol is here: https://t.co/IJfb2FAwYJ
>1300 recruits planned
#NITRICTrial #NITRIC #pedsCICU
Follow the presentation and tweet along folks! Its not often that a #PedsICU trial takes centre stage (like #FIRSTABC and @SANDWICHTrialUK did)
At least echoing @KathMaitland comment about baseline population. Has HFNC replaced oxygen as it was used previously-low flow systems? Caution to indicate HFNC when oxygen by any means would perform as well. #FIRSTABC #CCR22 Indication creep as named by @JAMyburgh
Had an amazing day at #CCR22 in Belfast. World class trials and discussion. #LOVITtrial #SuDDICUtrial highlights. Panel discussion with editors from @JAMA_current @NEJM @bronwenconnolly @seymoc @1791_mew about journal publishing. Can’t wait to present #firstabc tomorrow! @ICNARC
The #PICUJournalWatch #PICUJW collection for month of April 2022 has landed at https://t.co/G03pbucdo5 and in the #PICCHub app
#PedsICU #PedsCICU #NeuroPICU #SoMe4MV.
#FIRSTABC is the article of the month:
https://t.co/1sEWdVc7Q8
I am v excited to be talking at #SCCM22 today at 5pm UK time on #firstabc trial of #hfnc vs #cpap for post-extubation support in #PedsICU. Will the trial change your practice?@ICNARC @JAMA_current @NIHRcommunity @ImperialMed https://t.co/6JrrkqpXjh
@abusultaneh @AGMRRT @Martin_Kneyber @GEmeriaud @RobyKhemaniMD @CritCareReviews @JAMA_current 1/2 My views on a really interesting discussion: 1) risk-strat based on prediction of reint is logical next step, but what is 'high' risk? #FIRSTABC population 48 hr reint rate: ~12%, so clinician decision (pragmatic inclusion) did pick up a group >10% risk. ?high risk = >15%?
@nicola_taylor28 @nottmchildrens Thanks! The #firstabc step-up trial in critically ill children (PICU/hdu) will be presented @CritCareReviews #ccr22 in June. Outside critical care - is there still equipoise for #hfnc vs #cpap? Would clinicians randomise patients to receiving cpap? Keen to know!
PCCOT @nottmchildrens - great paper re HFNC vs CPAP. #FIRSTABC Are you planning on looking at indicators for HFNC outside the ICU setting?
Results of #FIRSTABC clinical trial comparing #HFNC vs #CPAP in extubated children in #PedsICU were presented in a livestream @CritCareReviews yesterday and published in @JAMA_current simultaneously.
https://t.co/TE8cfhGXzg
https://t.co/I5bynMqd69
A 🧵from the 🐴's mouth...1/9
@pic_pram @JAMA_current The edited version of the livestream recording is now available
https://t.co/DbIkTyRa0r
Supported by @MyIntensiveCare
#FIRSTABC
2⃣ We know very little about what the best first-line method is to support breathing in #PedsICU children who are just coming off a #ventilator. #hfnc and #cpap are used variably. #FIRSTABC compared them in the first and largest ever such #RCT. Trial funded by @NIHRresearch 3/9
1⃣ #FIRSTABC would have been impossible without the contribution of staff from 22 dedicated UK #PedsICU, @ICNARC @pus27 @lyvonnetume @rgfeltbower @Alvin_R_B @PaulMouncey @KathyRowan101 @DavidHarrison80 #KevinMorris #PeterDavis #ZiaSadique #RGrieve #KarenThomas #JulieLester 2/9
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