Top Tweets for #GUIDEHF
Hemodynamically-guided #HeartFailure management decreases HF-related endpoints across the ejection fraction spectrum in an expanded patient population of patients with #HF. https://t.co/Bi2DLTX8nk
#JACCHF #GUIDEHF #CardioTwitter
@drjohnm @AndrewJSauer @US_FDA Here is the detailed answer to your question from the #GUIDEHF investigators. Patients with HF in the control arm objectively "healthier" during the pandemic phase at least in some ways: event rates lower, PA pressures lower
https://t.co/Q6JA4dgmvu
Want to learn more about the expanded #CardioMEMS indication?
Hear Dr. Kunjan Bhatt of @AustinHeartTX discuss #GuideHF results and the benefit to #HeartFailure patients on the new episode of "Between Two Ventricles": https://t.co/idZm2RFteU
Safety Info: https://t.co/fRPpFrxTEd
With an expanded indication from @US_FDA, the benefits of the #CardioMEMS HF System are now available to even more #HeartFailure patients.
Learn more about the expanded indication and our #GuideHF trial at #ACC22: https://t.co/hDT8EdTKYO
Safety Info: https://t.co/fRPpFrgiMF
ICYMI: #CardioMEMS received an expanded indication from the @US_FDA, allowing earlier intervention using pre-symptomatic data.
See the latest on clarity in #HeartFailure care and learn about our #GuideHF trial: https://t.co/0G1N2TCaOl
Safety Info: https://t.co/fRPpFrgiMF
Watch cutting-edge data from #SWISSAPERO #OPTPEACE and #GUIDEHF at 11:00 AM ET. Featuring Drs. Yaling Han, Michael Zile and @RobertoGalea7 #TCT2021 @StephenEllis51 @ditchhaporia @DJ_Lakkireddy @robebyrne @SDoshiMD @NMHheartdoc @JACCJournals https://t.co/KPrUpQd7bW
Congratulations to Kunjan Bhatt, MD for being named a 2021 HFC/HFSA TOP PI of the year for his work with GUIDE-HF and RELIEVE-HF!!! @HFSA @AustinHeartTX @LindenfeldJoann #GUIDEHF #RELIEVEHF 👏👏
Full List of Winners: 🔗👇
https://t.co/s4yFoALpmP
My take on #GUIDEHF -
❌did not meet primary endpoint
✅reduction in HF🏥in pre covid analysis
✅effect similar pEF/rEF
❌no significant interaction pre/post covid so the pre covid analysis seems cherry picking
▶️CardioMems remains most useful in CHAMPION population
#GUIDE-HF trial: haemodynamic guided management may reduce #heartfailure hospitalisations in patients with earlier stage #HF #ESCCongress
In regards to Guide-HF
Here is a video about CardioMEMs if you are not familiar with the device!
#HeartFailure #CHF #GuideHF @escardio @mmamas1973 @TCTMD #Cardiotwittwr #Cardiology @mirvatalasnag @HFpEF @crfheart @CardioBot @BotPci @EPeeps_Bot @preventfailure @CircHF
CardioMEMS en HFrEF y HFpEF disminuye riesgo de hospitalización solo en era precovid. No impacto en mortalidad #GUIDEHF #ESCCongress
#GuideHF illustrates the big challenges our trials have faced during the Covid pandemic, not only in recruitment & execution of trial protocol, but also in estimated event rates. All of these impact the estimated treatment effect #ESCCongress #HF @JJheart_doc @mmamas1973
In randomized arm (single-blind #GuideHF #RCT in 1000 NYHA II-IV patients), implantable PA pressure sensor (#CardioMEMS) did NOT signif ⬇️ primary composite endpoint
Time-Tx interaction: Event rates ⬇️ during Covid, may have ⬇️ estimated Tx effect #ESCCongress @HeartOTXHeartMD
Results from GUIDE-HF Trial: Primary End point was not met in the overall anslysis #ESCCongress2021 #GuideHF Trial @TKDsosyal @vaytekin @doctormutlu @cardioceptor @canyucelkarabay @EnverAtalar @DursunAras2 @gokselcinier @umityasarsinan1 @LaleTokgozoglu @jeanlucvachiery @escardio
Ok, @frankruschitzka gave a rapid-fire review of #GUIDEHF at #ESCCongress following Dr. Lindenfeld, & @TheLancet editors Stuart Spencer & Rory Collins also had insights. I'm updating my story. Surprised no one weighed in on the patient blinding issue.
https://t.co/WsOgrfYaO7
Even though #GUIDEHF is a neutral study, it is super-important.
We should shift our focus from managing #HeartFailure patients based on their LV filling pressures to up-titrating prognosis-modifying drugs (and volume).
#CardioTwitter @drjohnm
Hot Line - GUIDE-HF
#ESCCongress #ESCDigital
The GUIDE-HF is intended to demonstrate the effectiveness of the CardioMEMS™ HF System in an expanded patient population including HF patients
@ESC_Journals @escardio @Steph_Achenbach @lamcardio @BiykemB @NMHheartdoc @ShelleyZieroth
GUIDE-HF TRIAL & CardioMEMS™ System in HF patients & The incidence of HF events was significantly reduced in the pre-COVID-19 with impact analysis (HR 0.76, 95% CI 0.61-0.95) #GUIDEHF @escardio @TKDsosyal @ihtanboga @canyucelkarabay @MeralKayikcoglu @doctormutlu @gokselcinier
#ESCCongress #HOTLine #GUIDEHF
Dr. Lindenfeld @VanderbiltU
🫀 CardioMEMS implanted in HFrEF & HFpEF
🫀 Endpoints: HF events/Mortality
🫀 37.6% women; no diff in baseline characteristics
#GUIDEHF results with #cardiomems on @TCTMD.
@escardio #ESCCongress
GUIDE-HF: Pulmonary Artery Sensor May Help in Mild HF, but COVID-19 Muddies Water
https://t.co/WsOgrfYaO7
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