Top Tweets for #GuPath
borrowing from #liverpath depiction of glutamine synthetase staining in FNH, this is what I call "map-like" CA9 staining in #GUpath nephrectomy papillary RCC
(being part of HIF pathway, CA9 can be + in areas of ischemia/necrosis!)
🚨😳🔬
The MiT/TFE family of transcription factors comprises MITF, TFE3, TFEB, and TFEC.
MITF/ TFE3/ TFEB-altered RCC have been reported.
Possibly, the first report of TFEC-rearranged RCC (@Human_Pathology)?
https://t.co/ujjtMkgbaF
Thightly packed glands of acinar prostatic adenocarcinoma mimicking cribriform GG4...the way to tell them apart is to look at high magnification and find/exclude the surounding stroma/collagen bundles (marked with green in the last picture)
#pathology #GUpath
There's still a LOT to learn about renal low-grade oncocytic tumors
IJSP read of the day: "Low-Grade Oncocytic Tumor (LOT): Clinicopathological, Morphological, Immunohistochemical and Cytogenetic Study of 17 Tumors" (Gutiérrez et al.): https://t.co/P5WszreLdr
#GUPath #PathTwitter
Thank you @Histo_Journal and @BritishDivIAP 🙏🏻
This new paper on Updates and controversies in contemporary grading clear cell #RCC and papillary RCC is OPEN ACCESS. #GUPath👇👇👇
An in-depth discussion of the challenges that pathologists may encounter when grading clear cell renal cell carcinoma and papillary renal cell carcinoma, with a focus on the WHO/ISUP grading system and attention to recent updates. #gupath @GladellPaner https://t.co/rD7Ok8rp0n
Go to https://t.co/FGDgH231q4 to see more of the case! #gupath #pathtwitter #ISUPCOTM
Authors: Ting Zhao, MD, Kyle M. Devins, MD; Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA @TingZhaoPathdoc @md_kyle
An in-depth discussion of the challenges that pathologists may encounter when grading clear cell renal cell carcinoma and papillary renal cell carcinoma, with a focus on the WHO/ISUP grading system and attention to recent updates. #gupath @GladellPaner https://t.co/rD7Ok8rp0n
Solo palabras de agradecimiento para una jornada llena de magia , talento y mucha inspiración. Gracias @MerceJorda1 @MauroSaieg @CDinares @juan_astigueta @IPena19485 @citologiala #SomosSLAC #Somosfamilia
🧩 Urethral riddle
Female urethral lesion. 🤔
We see a glandular proliferation in the urothelial tract.
How many differentials can you think of?
And what would be your diagnosis in this case?
One related case is attached for comparison. 👇
#DxMindMap #GUPath #UrethralPath #PathTwitter @JHUpath
This is a crazy case of bladder cytitis cystica et glandularis with extensive intestinal metaplasia and low-grade dysplasia. It resembles a colorectal adenoma! There is lots to learn in Dr. Alex Kryvenko's new book. Get yours at https://t.co/11aBMJXEmQ #UMiamiPath
@MauroSaieg 👰🏻♀️ 🤵🏻♂️ citología de orina + IA @citologiala @milyabadli 👀 👂
#GUpath #cytopath #cytopathology
Grossing night, holy night, and a holy specimen...
A woman in 60s, history of hypertension, presented as unilateral atrophic kidney. Impression of urologist on request form: nonfunctional kidney due to complete staghorn stone
What's your diagnosis?
#PathTwitter #PathX #GUpath
No todo puede ser malo 😇 vs 😈 Que nos cuentan las orinas cuando no hay tumor? @CDinares @SECitologia fantástica presentación 👏🏼 @citologiala #GUpath #cytology #cytopath #cytolovers #SLAC #SEC
@MerceJorda1 @univmiami TPS The Paris System 2.0 @citologiala @CDinares @SECitologia viernes de primavera con una dosis de citología #GUpath #CytoPath #CytoLovers #SEC #SLAC
#GUpath TURBT (h/o urothelial neoplasia):
urothelial carcinoma in situ with superficial LP invasion?
nope!
it's CIS ➕#beautyinb9 nephrogenic adenoma
⏬cont'd⏬
Now in press in Virchows Archiv-->Multi-institutional cohort of 18 renal tumors, uniquely ALL with proven FLCN biallelic inactivation -> morphology, molecular, IHC, and clinical follow-up.🔬
@ESP_Pathology @GU_Path_Society @IntSocUropath
#kidneycancer
#BHD #birthoggdube #gupath
🧩 Bladder riddle
Bladder tumor with a heavy inflammatory background and mixed inflammatory cells. 🤔
Reactive process?
Should I call my hematopathology colleague? 👀
What would be your diagnosis?
#DxMindMap #BladderTumor #GUPath #PathTwitter @JHUpath
🧩 Bladder riddle — Part 2
🍎You all got the last one right— LCH.
Here’s another:
Bladder mass. Unusual location.
Look closely — “binge-eating, starving” cells 👀
What’s the diagnosis? 🤔
#DxMindMap #BladderTumor #GUPath #PathTwitter @JHUpath
#GUpath prostate bx:
telescoping PNI - mimic of glomerulation (not pattern 4)
How to grade prostate cancer in small biopsy specimens remains one of the most challenging and controversial areas in daily urologic pathology practice.
This recent review article published in Urologic Clinics of North America,
“Prostate Cancer Grading: An Update,” by Drs. John Hanna, Gennady Bratslavsky, Jeffrey S. Ross, Oleksandr Kravtsov, provides an excellent practical overview of many real-world diagnostic dilemmas encountered in prostate biopsy interpretation.
The review discusses contemporary Gleason grading, Grade Groups, quantification of Gleason pattern 4, cribriform morphology, intraductal carcinoma, grading pitfalls in minute tumor foci, interobserver variability, and emerging AI applications in prostate pathology.
Article link: https://t.co/rs5EwjMDkF
A remarkable milestone - inspirational! Congratulations to @LiangChengMD and all of your collaborators.
@BrownPathology @BrownUniversity #GUPath
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