Top Tweets for #HDaC
@halno488603 千葉工業大学と藤田医科大学
怪しいですね😡
伊藤穣一はエプスタインから20年間で80万ドル資金提供されたようです
電子カルテや個人の健康データを集積する目的はトランスヒューマニズムが目的だったりね🔥 #HDAC #人工知能
https://t.co/0n9HKKv449
https://t.co/FrWsbk62f5
Livia Stanger and Colleagues Link CS014 to in Vivo Thrombosis
@JTHjournal
https://t.co/Yzekj3vLW0
#CS014 #HDAC #Health #Hematology #Hemostasis #HemostasisNews #HemostasisToday #Histone #Medicine #Thrombosis #MedEd #MedX
Happy to share our publication dealing with the targeted #HDAC degradation via direct DDB1 recruitment. Congrats to first author Shiyang @Vincent_SYZ and everybody involved. Great collaboration with the Geyer lab @Geyer_lab! #BonnTPD https://t.co/REXCIwcFDB
🧪 #FBS New Research!
Inhibitory Effect of Novel Dihydroxamate Derivatives for Histone Deacetylase 1
🔹 HDAC1 inhibition
🔹Drug discovery
🔹Epigenetic regulation
✍️Sung-Kun Kim (@RiverHawkSports ), Jhawn G. Saul
🔗https://t.co/OrwE09AEe8
#Epigenetics #HDAC #HistoneModification
Just got my confirmation for Global Fabric Day 2025: Gurgaon Edition! 🔥
Hosted by @MSFTIndia communities & powered by awesome sponsors like AtiSunya, Packt & BIWORLD.Can’t wait to connect, learn, and sweat (a bit 😅) on May 31!
#MicrosoftFabric #HDAC #DataCommunity #Gurgaon
Blocking dyneins in #VSMCs could become the best #vasodilator in the future by inhibiting #retrograde #trafficking of #ion #channels and membrane receptors.? 😊🔬
#HDAC-6 inhibitors: beneficial or controversial in the future management of #hypertension?
Selective or nonselective? 🧬🔬🧬
@APSPhysiology @AJPRenal @atvbahajournals @AsAshraf123321 @ASH_hematology @atheroaussie @ATHjournal @BMVBSoc @HaoYin20 @DengyueEcho @MetabolismAnd @landen_xu @WashUCardiology @Hiraselab_KU @CMPLPUCCHILE @LuisSobrevia2 @vascularbiology @AlisaAn46097029 @AChCiencias @Ahmed43101178 @AHAScience @HyperAHA @HypertensionAus @JAHA_AHA @CTRC_UofSCSOM @hopkinsheart 👇🧵👇🧵
#Hypertension #SmoothMuscleCell #Microtubule
Spontaneous Hypertensive rat Mesenteric Artery
#Acetylome
TUBA1A α-tubulin K40Ac⏫
Tubacin HDAC6i➡️
⏫AcTubulin➡️
⏫endothelium-dependent vasorelaxation (like via ⏫eNOS◀️Chen J, JBC 2019)
⏬endothelium-independent relaxation (via⏫SMC MT stability?🧐)
⏫U46619 (TXA2 receptor agonist)-induced contractility (only in the presence of L-NAME eNOSi)
Neither Tubacin nor Taxol alters SMC surface stiffness #ScanningIonConductanceMicroscopy
Any effect of Tubacin on blood pressure?😁
@tajepps 2024
https://t.co/sZFEaJNQIX
Blocking dyneins in #VSMCs could become the best #vasodilator in the future by inhibiting #retrograde #trafficking of #ion #channels and membrane receptors.?
#HDAC-6 inhibitors: beneficial or controversial in the future management of #hypertension?
Selective or nonselective? 🧬🔬🧬
Day 2: Two Upcoming Sessions at 06:00 PM IST, 11 May 2025 at 🌍 Global Microsoft Analytics Community Conference 2 – Online Event 🌍
Azure cost control: https://t.co/jTFckfhT6z
Connect with Purpose: The What, Why, and How of Powerful Networking: https://t.co/vmb3RZ8nno
#HDAC #IndiaFabricUserGroup #MicrosoftFabric #Copilot #Purview #PowerPlatform #DataAnalytics #AI #GlobalConference #DataCommunity
Thanks for your support on Day 1! We have interesting sessions lined up for tomorrow — 30 of them.
We will start at 7:00 AM IST with two sessions. Do join us!
📊 This Power BI report provides all the links:
https://t.co/272NhPM4a9
#HDAC #IndiaFabricUserGroup #MicrosoftFabric #Copilot #Purview #PowerPlatform #DataAnalytics #AI #GlobalConference #DataCommunity
Happy to share the final version of our DCAF11-recruiting #HDAC #PROTAC paper. Congrats to my co-workers Felix @fellerflix, Heiko, Martina, Irina and Maria! https://t.co/FpEcengXMi
Excited to share our latest work on an exquisitely selective #PROTAC of #HDAC6 in #JMedChem @ACSBioMed @ACSPublications!! TO-1187 is a highly potent HDAC6 degrader with complete proteome selectivity, sparing all #CRBN neosubstrates and other #HDAC isoforms.
The next chapter of our HDAC #PROTAC story: CRBN-recruiting PROTACs based on a non-selective ethylhydrazide #HDAC warhead induce selective HDAC6 degradation. Congrats to my PhD students Daniel @danicious & Irina (co-first authors), and Felix @fellerflix. https://t.co/Y63stzUlx9
Excited to share our latest publication on #HDAC inhibitor-based multineurotarget drugs as a potential treatment option for Alzheimer´s disease, now online in ACS Pharmacology & TS! 🎉 Huge congrats to our amazing team and collaborators! https://t.co/B6jE9rdyw1
Happy to announce that our paper on the multicomponent synthesis of quisinostat analogs as anticancer and antiplasmodial #HDAC inhibitors has been published. Congratulations to first author Daniel @danicious and all co-workers and collaborators involved! https://t.co/jshw1mz2fV
@ACSPublications @UiB @UniFreiburg It had been shown by thermal profiling that the approved HDAC inhibitor Panobinostat has phenyalanine hydroxylase as a relevant off-target #hdac https://t.co/3AfNoXf5HA
Really glad to see this perspective out! Was excellent working together.
On to the next! #HDAC #CovalentInhibition
Inhibitors of histone deacetylases (#HDACs) have longer and longer on-target residence times, which may help future clinical applications.
How is this achieved? Check out our new #OpenAccess Perspective @JACS_Au, with @DrYasirRaouf, to know more! 👇🏻
https://t.co/UeLChzzamz
New PhD alert🚨 Dr. Lauren Kotsull successfully defended her dissertation at #wsuchemistry. Lauren plans to remain at the @PflumLab through the end of the year to finish up a publication she is working on. Congratulations, Dr. Kotsull! #ChemBio #HDAC #chemistryindetroit
Excited to share our new preprint on the multicomponent synthesis of quisinostat analogs as anticancer and antiplasmodial #HDAC inhibitors. Congratulations to all co-workers and collaborators, especially first author Daniel @danicious - https://t.co/k0O0e0SJPu
"A demonstration project near Shafter is testing tech for #CDR without need for water — a big advantage in Kern, which has plenty of the resources required except that one. Water is actually produced as part of what Avnos Inc. calls hybrid direct air capture, or #HDAC.
Avnos' machine dehumidifies air before using chemicals to soak up CO2. Heat produced in the process is then redirected for use in releasing the gas and water.
The model being tested north of Bakersfield, called Project Alpine, collects but does not currently store CO2. With a capacity of 30 metric tons of CO2 per year, it makes five times that amount of distilled water, or about 39,626 gallons per year."
Details:
https://t.co/vZ90MTykPP
Very happy that my co-workers Linda and Felix could contribute #HDAC inhibition and viability assay data to this exciting project led by the Mahboobi lab! https://t.co/r1Z5Q9OQPs
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