#Herg - Twitter Hashtag

about 2 months ago

🚨 New paper in @J_A_C_S! Using nonequilibrium molecular dynamics, we uncover atomistic steps underlying C-type inactivation in cardiac hERG channels, providing new insight into channel gating. 🔗 https://t.co/S9eJFqMffF #MolecularDynamics #hERG

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Acta Pharmaceutica Sinica B @ActaPharmSinB

4 months ago

Article✍️#Scaffold hopping yields novel #furo[3,2-d]pyrimidine #NNRTIs with optimized #antiviral #potency, enhanced selectivity, and reduced #hERG #liability. From Dr. Chen @FudanUniversity; @Sciencedirect; @ElsevierConnect. https://t.co/rJt0V9vlyz.

ActaPharmSinB's tweet photo. Article✍️#Scaffold hopping yields novel #furo[3,2-d]pyrimidine #NNRTIs with optimized #antiviral #potency, enhanced selectivity, and reduced #hERG #liability. From Dr. Chen @FudanUniversity; @Sciencedirect; @ElsevierConnect.
https://t.co/rJt0V9vlyz. https://t.co/bblI0Cppcm

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Dr. Ajay Vikram Singh, Senior Scientist at BfR

@avikrams

over 1 year ago

Revolutionizing drug safety with AI! Our new IEEE Access article dives into cutting-edge machine & deep learning for hERG blocker prediction, tackling cardiotoxicity head-on. Check it out! [link to article] #MachineLearning #DrugDiscovery #hERG #AIinHealthcare. doi: 10.1109/ACCESS.2025.3566440

avikrams's tweet photo. Revolutionizing drug safety with AI! Our new IEEE Access article dives into cutting-edge machine & deep learning for hERG blocker prediction, tackling cardiotoxicity head-on. Check it out! [link to article] #MachineLearning #DrugDiscovery #hERG #AIinHealthcare. doi: 10.1109/ACCESS.2025.3566440

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Billy Noonan @Dr_BillyWN

about 2 years ago

🚨 New Paper 🚨 "Potassium dependent structural changes in the selectivity filter of #HERG potassium channels" 👇 https://t.co/qbTNYelnCu Well done @tobywilliamall1, @VandenbergJamie @EmelieJFlood @alastairstewart and everyone! #EnhancedSampling #MolecularDynamics #HerG #CryoEM

Chai Ng @ChaiAnn_Ng

about 2 years ago

A significant effort to understand the rapid inactivation of hERG channels lead by @VandenbergJamie @CarusL Mark Hunter and our collaborators @tobywilliamall1 @EmelieJFlood @Dr_BillyWN Karen Corbett, @alastairstewart Eduardo Perozo. Exciting times ahead! https://t.co/2E8oTt0Rac

ChaiAnn_Ng's tweet photo. A significant effort to understand the rapid inactivation of hERG channels lead by @VandenbergJamie @CarusL Mark Hunter and our collaborators @tobywilliamall1 @EmelieJFlood @Dr_BillyWN Karen Corbett, @alastairstewart Eduardo Perozo. Exciting times ahead!
https://t.co/2E8oTt0Rac https://t.co/cqePgUDHTX

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UCL Anthropology @UCLanthropology

over 2 years ago

Join us tomorrow at 14:00 for a Human Ecology Research Group Seminar on ‘How, Why and When Conservation Initiatives Go to Scale’ with Dr Morena Mills! Link to the seminar series: https://t.co/aVFCXWGdiG #humanecology #HERG #seminar

UCLanthropology's tweet photo. Join us tomorrow at 14:00 for a Human Ecology Research Group Seminar on ‘How, Why and When Conservation Initiatives Go to Scale’ with Dr Morena Mills!

Link to the seminar series: https://t.co/aVFCXWGdiG

#humanecology #HERG #seminar https://t.co/842uwV56Ob

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Whitney Stevens-Sostre, PhD Boricua 🇵🇷 @StevensSostre

almost 3 years ago

Delighted to share my first co-first author publication and the final part of my PhD thesis! Together with @lisi8810, we uncovered an intersubunit ‘hydrophobic nexus’ formed between cytosolic domains that regulates #hERG channel slow deactivation gating https://t.co/HwqsYbrivF

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Dr Alpha Grace @DrAlphaGrace

about 3 years ago

C'est une preuve claire que les nations occidentales et leurs dirigeants inhumains n’ont pas de respect pour la vie de leurs citoyens et encore moins pour celles des autres nations. Le mal est au cœur de #Biden, #Macron, #OlafScholz, #Sunak, #Herg, #BenjaminNetanyahou #Génocide

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Prof. Dr. Serdar Durdağı @serdar_durdagi

about 3 years ago

Our paper on new hERG blocker models using ML-based classifiers has been accepted at the ACS Omega #durdagilab #drugdesign #hERG

serdar_durdagi's tweet photo. Our paper on new hERG blocker models using ML-based classifiers has been accepted at the ACS Omega #durdagilab #drugdesign #hERG https://t.co/ikjgKwx0WE

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Whitney Stevens-Sostre, PhD Boricua 🇵🇷 @StevensSostre

over 3 years ago

Hi #BIBPSRollCall! My name is Whitney and I’m the founder of #BlackInBiophysics. I’m a new Neuro #PhD graduate @UWMadison. I studied #hERG channels 🫀 using #ephys. I’m a new mom & postdoc studying the mechanisms of circuit establishment and function in the mammalian retina 👁️

StevensSostre's tweet photo. Hi #BIBPSRollCall! My name is Whitney and I’m the founder of #BlackInBiophysics. I’m a new Neuro #PhD graduate @UWMadison. I studied #hERG channels 🫀 using #ephys. I’m a new mom & postdoc studying the mechanisms of circuit establishment and function in the mammalian retina 👁️ https://t.co/3f3sKgAQgl

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Sophion Bioscience A/S @sophionbio

over 3 years ago

@Metrion_Biosci recently developed a #hERG ion channel assay on @sophionbio's #Qube384 to screen compounds at physiological body temperature (37oC). Read more and download the poster here: https://t.co/qIzAoNGaPv

sophionbio's tweet photo. @Metrion_Biosci recently developed a #hERG ion channel assay on @sophionbio's #Qube384 to screen compounds at physiological body temperature (37oC).

Read more and download the poster here: https://t.co/qIzAoNGaPv https://t.co/dySoZRftlv

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nanoCAFÉ Group @HyGate_ERC

over 3 years ago

On @SapienzaRoma the article on the recent publication "Noncanonical #electromechanical coupling paths in #cardiac #hERG potassium channel" on Nature Communication funded by @ERC_Research https://t.co/yuCnCDCbOY

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nanoCAFÉ Group @HyGate_ERC

over 3 years ago

🗣️New paper "#Noncanonical #electromechanical coupling paths in #cardiac #hERG potassium channel" published with @SpringerNature in out now! 👏👏👏@AlbGiacomello and @EffeCosta from @SapienzaRoma with Prof. Bezanilla's group from @UChicago. @ERC_Research https://t.co/Ad4qS7jFtm

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akumawat @aim_it_kumawat

over 3 years ago

Hey #bps2023 folks, visit my poster to know how we can use molecular information from gain of function mutations (SQT) to design therapeutics to treat LQT2 in #hERG K+ channels. #MDsimulations #drugdiscovery #ionchannel Feb 21st Tuesday @ 1.45 PM Poster no. : B293

aim_it_kumawat's tweet photo. Hey #bps2023 folks, visit my poster to know how we can use molecular information from gain of function mutations (SQT) to design therapeutics to treat LQT2 in #hERG K+ channels. #MDsimulations #drugdiscovery #ionchannel
Feb 21st Tuesday @ 1.45 PM
Poster no. : B293 https://t.co/jCp9wt79eS

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Sally Kift @KiftSally

almost 4 years ago

🤔CMM @SRMatchett #HERG Houghton: Cost & acad consequences of Block Teaching Re @victoriauninews @AdamShoemakerVC & @SCUonline Roche @erica_scu @LizSGoode -Rare sector⬆️in edu productivity w Block Model due to⬇️student attrition +⬇️net costs 👉50%⬆️4 VU! https://t.co/Zr0XVbB5aF

KiftSally's tweet photo. 🤔CMM @SRMatchett
#HERG Houghton: Cost & acad consequences of Block Teaching
Re @victoriauninews @AdamShoemakerVC & @SCUonline Roche @erica_scu @LizSGoode
-Rare sector⬆️in edu productivity w Block Model due to⬇️student attrition +⬇️net costs
👉50%⬆️4 VU!
https://t.co/Zr0XVbB5aF https://t.co/suF3nBc9eh

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T. Makana Chock @Doc_Chock

about 4 years ago

First (okay 2nd) day of school @NewhouseSU all school gathering in the #Herg

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Royal Society Publishing

@RSocPublishing

about 4 years ago

Using mathematics, Dominic G. Whittaker & colleagues simplify a model of the cardiac human #hERG potassium ion channel: https://t.co/qeTnJK6zIw @UoNCMMB @SFU #Interface

RSocPublishing's tweet photo. Using mathematics, Dominic G. Whittaker & colleagues simplify a model of the cardiac human #hERG potassium ion channel: https://t.co/qeTnJK6zIw @UoNCMMB @SFU #Interface https://t.co/YiFbSKPrLk

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Peter Kenny 🇹🇹🇬🇧🇧🇷🇺🇦🌻🇪🇺🇲🇦🇬🇱 @pwk2013

over 4 years ago

Probabilistic categorical (#hERG IC50 > 20 μM) #CompTox models can't generally be validated and are of minimal use to #MedChem when addressing known (hERG IC50 measured for project compounds) safety issues #DrugDesign #DrugDiscovery #cheminformatics #chemoinformatics #ML #AI

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Sophion Bioscience A/S @sophionbio

over 4 years ago

Temperature in #IonChannel experiments can be critical. In a Sophion application report, the conductance, kinetics, & pharmacology of the #hERG ion channel current, a critical component of the cardiac action potential, were recorded at 22°C & 35°C. https://t.co/vgZjgpNkFF

sophionbio's tweet photo. Temperature in #IonChannel experiments can be critical. In a Sophion application report, the conductance, kinetics, & pharmacology of the #hERG ion channel current, a critical component of the cardiac action potential, were recorded at 22°C & 35°C. https://t.co/vgZjgpNkFF https://t.co/pLYQfnbLIb

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Lhasa Limited @LhasaLimited

over 4 years ago

QMRFs for Derek Nexus 6.2 and Sarah Nexus 3.2 are now available to download from our website! View all our latest QMRFs here: https://t.co/DKHrlui0L7 #QMRF #Mutagenicity #Carcinogenicity #HERG

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Chai Ng @ChaiAnn_Ng

over 4 years ago

Registration for CCG2022 @clingen is open and I will present my calibrated KCNH2 functional assay using #SyncroPatch384 and describe the result of 458 SNV in exon 2 of #KCNH2 for interpreting mutational hotspot in this exon which encodes PAS domain of #hERG K+ #ionchannels

ChaiAnn_Ng's tweet photo. Registration for CCG2022 @clingen is open and I will present my calibrated KCNH2 functional assay using #SyncroPatch384 and describe the result of 458 SNV in exon 2 of #KCNH2 for interpreting mutational hotspot in this exon which encodes PAS domain of #hERG K+ #ionchannels https://t.co/9Wt0Uh6bz7

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