Top Tweets for #IvIg
Long Covid患者
”➡️ 高用量の #IVIG(免疫グロブリン静注療法)後、疲労感は解消、認知機能も正常化、その後1年間で生活の質も回復。
➡️臨床的改善に伴い、炎症マーカー、自己抗体、およびT細胞・単球複合体の数値も低下。
https://t.co/xdP3V1c7nu

”#LongCOVID は、免疫系が「活性化された状態」のままであることが原因となっているのか?
➡️ 症例報告:39歳男性
ブレインフォグ、異常な倦怠感、自律神経症状といった重度の LongCOVID症状
自己抗体やT細胞と単球の異常な相互作用など、顕著な免疫異常が確認”
https://t.co/LM1Dgz8fbS
🔬 Just Published | JCA
Intravenous immunoglobulin use and in-hospital outcomes in adult fulminant myocarditis: a two-center retrospective cohort study
Corresponding author: Prof. Dao Wen Wang (China)
🔗 https://t.co/y15NT5H3zk
#FulminantMyocarditis #IVIG

Exemplary institutional partnership for health: @AHRI_ETH & @ebtbs64755 signed MoU to strengthen R&D and innovation in #bloodsafety, #plasmaderivedproductsdevt, #IVIG, & #translationalpublichealth.
https://t.co/VFow8kRBC2
@FMoHealth
@WHOEthiopia
@AfricaCDC
@WHOAFRO
@WHO

In medical reality, the therapeutic effects of #IVIG (hdIVIG) are temporary because the body naturally metabolizes and clears bABs. IVIG is not a treatment for viral persistence, but it could be used as a supportive #LongCOVID therapy to target secondary complications. #WearN95
Could #LongCOVID be driven by an immune system that remains “switched on”?
➡️ A remarkable case report describes a previously healthy 39-year-old man with severe LongCOVID—brain fog, disabling fatigue and autonomic symptoms—who showed marked immune abnormalities, including autoantibodies and abnormal T-cell–monocyte interactions.
➡️ After high-dose #IVIG, his fatigue normalised, cognitive function returned to normal and his quality of life recovered over the following year.
➡️ These clinical improvements were accompanied by reductions in inflammatory signals, autoantibodies and T-cell–monocyte complexes. 1/

For many people with myositis, IVIG is an important part of treatment. Knowing what to expect can make the experience less overwhelming.
If you or a loved one is preparing for IVIG, ask questions and understand your treatment.
@docrota
#MyositisIndia #IVIG #MyositisAwareness


【第44回 #IVIg とは?】
IVIg(Intravenous Immunoglobulin:静注. #免疫グロブリン療法)は、多くの健康な方の血液から精製した免疫グロブリン(IgG)を点滴で投与する治療です。
大量の免疫グロブリンを投与することで、過剰になった免疫反応を調整し、神経の炎症を抑える働きがあります。
MS、NMOSD、MOGADでは位置づけが少し異なりますが、特にMOGADの再発時や再発予防などで用いられることがあります。
副作用として、頭痛、発熱、吐き気などがみられることがあります。まれですが、血栓症や腎機能障害などにも注意が必要です。
IVIgは、ステロイドや血液浄化療法と並んで、病状に応じて選択される治療の一つです。
同じ神経免疫疾患でも、病気の種類や再発の重症度によって、適した治療は異なります。
#MS #NMOSD #MOGAD
Love seeing research backing what many of us pre-Covid autoimmune SFN #IVIG patients + Autonomic Neurologists have been saying since the early days. Successful treatment of vaccine-triggered immune mediated SFN with IVIG. (Yes it’s real, since long pre-Covid.) #Care4Complex
Can damaged small nerve fibres actually regenerate in post-Covid 19 vaccination syndrome?
➡️ A striking case report describes a woman with small-fibre neuropathy (SFN) following #BNT162b2 vaccination whose symptoms improved after 8 cycles of #IVIG, accompanied by a remarkable rise in intraepidermal nerve fibre density (IENFD)—from 6→9 fibres/mm at the ankle and 6→8 at the thigh. 1/

Can damaged small nerve fibres actually regenerate in post-Covid 19 vaccination syndrome?
➡️ A striking case report describes a woman with small-fibre neuropathy (SFN) following #BNT162b2 vaccination whose symptoms improved after 8 cycles of #IVIG, accompanied by a remarkable rise in intraepidermal nerve fibre density (IENFD)—from 6→9 fibres/mm at the ankle and 6→8 at the thigh. 1/

Keep Up The Good Fight my fellow Warriors. 🦾❤️ we got this. You matter, advocate for yourself. Subcutaneous Immunoglobulin currently going after 5 hours spent at the blood lab and cancer center earlier. #SubQIG #PID #immunodeficiency #IVIG

@heather4OakBay @Rheumat_Aravind #IVIG actually protects you significantly against infections, and is not immune suppressive. It only lasts a few weeks in your body. It does have potential for acute side effects like the dreaded aseptic meningitis, but it can be treated. Mostly causes bad headaches/fluiness.
Set #Care4Complex patients up for success w/ #IVIG:
1) Set realistic expectations re: speed of improvement
2) Using adequate dose + length of treatment
3) Mitigate side effects: slow infusion speed, more frequent/lower per dose infusion (or SCIG), plans for pre/post-meds
I hear things like this all the time from new #IVIG patients, and it makes me so sad - for patients and because of waste of such a precious resource. Patients are constantly being undertreated, guaranteeing failure. SFN/Dysautonomia requires 6-12 months of regular treatment.

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