Top Tweets for #KAT2B

over 1 year ago

✅Silencing #KLF4 or #STAT3β #expression inhibits the transition from #VSMC to macrophage-like VSMC and decreases #plaque #vulnerability. Could this be a radical and prophylactic solution to #atherosclerosis?🫰🐁🐁🧬 ✅By stimulating #KAT2B #overexpression in the plaque to improve its stability, what would subsequently be the likelihood of #thrombogenesis and #distal #occlusion? ✅Could the #biomarkers expressed in the #phenotype #transition, #αSMA and #CD68, be the next key players in the #early #detection of atherogenesis? @atvbahajournals @CircRes @CircHF @DiabetesCareADA @endothelialnews @gkolost @HaoYin20 @heartforallez @IEEEembs @J_Cell_Sci @JPBY_official @RockUPress @LuisSobrevia2 @CMPLPUCCHILE @FacMedicinaUC @SocFisiolChile @ALACFdifusion @society_eas @AtheroNL @britathsoc @Ahmed43101178 @StrokeAHA_ASA @drshafikuchay @WashUCardiology @WashUDeptMed @TrackYourHeart @CNIC_CARDIO @NatureCVR @CTRC_UofSCSOM @isth @JCVPOnline @EriKato71362632 @IJMS_MDPI @hopkinsheart @ry_saty @VesSurgery @seacv_esp @The_MCSociety 👇🧵👇🧵

Atherosclerosis @ATHjournal

over 1 year ago

RNA Splicing of the STAT3 by PCBP1 Promotes Vulnerable Plaque Formation via Macrophage-like Phenotype Modulation of Vascular Smooth Muscle Cell 🔗https://t.co/Q5afz6oecW @society_eas @ELS_Cardiology #EASSoMe

ATHjournal's tweet photo. RNA Splicing of the STAT3 by PCBP1 Promotes Vulnerable Plaque Formation via Macrophage-like Phenotype Modulation of Vascular Smooth Muscle Cell
🔗https://t.co/Q5afz6oecW
@society_eas @ELS_Cardiology #EASSoMe https://t.co/SpTUTVHqjE

Heme Today @HemeToday

over 1 year ago

In regulatory news on #Heme Today: @US_FDA has granted Fast Track Designation to #AUTX703 oral #KAT2A, #KAT2B degrader for relapsed or refractory #acutemyeloidleukemia. #AML, #AuronTherapeutics https://t.co/XOO0J5aCLd

一般社団法人日本癌学会 @jcaopl

almost 4 years ago

✨Cancer Science誌 10月のハイライト論文紹介No.3✨ NEDD4結合タンパク3（N4BP3）は、 lysine acetyltransferase 2B（KAT2B）との相互作用を介し、 STAT3の発現を亢進、肝臓がんの血管新生を促進し、腫瘍の悪性度を亢進させる。 https://t.co/d1lKwZfj7D #肝臓がん #血管新生 #N4BP3 #KAT2B

Top Tweets for #KAT2B

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