Top Tweets for #LEAPstudy
Younger siblings of participants in the LEAP Study show a tendency for #peanut #allergen sensitization. Introduction of peanuts in the first year of life can help reduce this effect. #PeanutAllergy #LEAPStudy #AAAAI24 https://t.co/9m90y99ovk
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#allergens #allergensweaning #allergenguide #eatstudy #leapstudy #foodallergies #anaphylaxis #evidencebasednutrition #bda #associationfornutrition
Research from @KingsCollegeLon — based on data from the landmark #LEAPstudy + data from a follow-up study — suggests that Staphylococcus aureus bacteria on the skin of young children with severe #eczema increases their chances of developing #foodallergy. Find out more: @GoAllergy
We first estimated the effect of early introduction at different ages for the observed results from #EATstudy and #LEAPstudy (randomised {LEAP] and screen failures [PAS]). Impact decreased with increasing age at introduction. 7/12
![ProfGRoberts's tweet photo. We first estimated the effect of early introduction at different ages for the observed results from #EATstudy and #LEAPstudy (randomised {LEAP] and screen failures [PAS]). Impact decreased with increasing age at introduction. 7/12 https://t.co/AlSxcH3VYH](https://pbs.twimg.com/media/FmTpWMQWYAAOuM-.png)
If the adherence in #EATStudy had been as good as in #LEAPStudy, peanut allergy would have reduced from 2.5% to 0.29%. EAT recruited from the general population - it demonstrates that most infants with peanut allergy are found in the very large low risk group. 6/12
Early introduction of peanut products resulted in
an 81% reduction in peanut allergy at 5 years in #LEAPStudy. Many infants though were excluded
because they already had peanut allergy. If all these infants were included in the analysis, there was only a 52% reduction. 3/12
Latest paper from #LEAPStudy is now published in @JACIonline. We have looked at what happens if peanut products are introduced into the infant diet at different ages across the whole population. https://t.co/zpOlrNHOSi
https://t.co/xDIgYjezyS
More details below. @GoAllergy 1/12
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#vegetarianchildren #veganchildren #leapstudy #eatstudy #allergiesinbabies #allergiesinchildren
#EAACI2020: Today I am going to tweet about the EAACI Food Allergy Prevention Guideline update. Previous version was published in 2014. Field has changed hugely with #LEAPstudy. Update chairs: Susanne Halken & Antonella Muraro. @VenterCarina @GoAllergy @KateGrimshaw3
#EAACI2020 George Du Toit talking about preventing peanut allergy. Best time to introduce peanut into the infant diet is 4 to 6 months of life. Infants with any eczema are at increased risk, they should start around 4 months of age. #LEAPstudy #EATstudy @GoAllergy
#EAACI2020 George Du Toit: Staphylococcus aureus seems to be able to prevent the development of tolerance to peanut. @GoAllergy #LEAPstudy https://t.co/kgWWNQU52q
#EAACI2020 George Du Toit talking about tolerance. So tolerance can be achieved for food allergy. In the #LEAPstudy Trio Study, the RCT cohorts are being followed at 12-13 years. Have we achieved long term tolerance? @GoAllergy
#EAACI2020 George Du Toit talking about tolerance. Having a MALT1 gene polymorphism gives you a risk of 60% peanut allergy in #LEAPstudy. But peanut consumption can prevent this. An example of environmental - gene interaction for food allergy. @GoAllergy
#EAACI2020 George Du Toit talking about tolerance. In #LEAPstudy, the mean group peanut specific IgE level in the consumption group did not start to increase during the one year off peanuts. This suggests tolerance. @GoAllergy
#EAACI2020 George Du Toit talking about tolerance. Challenging endpoint with controversy about length of CESSATION of intervention to demonstrate tolerance (rather than desensitisation) has been achieved. In #LEAPstudy we chose a year, much longer than other studies @GoAllergy
#EAACI2020: Michael Perkin on over the counter prevention weaning products: very variable doses of food proteins, have other component, often contain peanut flour which was not used in #LEAPstudy #EATstudy and are very expensive compared to normal food. @PaedAllergy
#EAACI2020: Michael Perkin: over the counter allergy prevention weaning products: FDA have now allowed a health claim for one of these products. Michael reviews the current products critiquing them. Worryingly not all follow LEAP / EAT regime! @PaedAllergy #EATstudy #LEAPstudy
#EAACI2020: Edmond Chan on implementation challenges: Australian Early Nuts study in the - most infants are being started on peanuts in the first year of life. Great example of implementation of #LEAPstudy research findings. More soon from EAACI Prevention Guideline @GoAllergy
#EAACI2020: Gideon Lack now talking about the remaining questions in preventing peanut and egg allergy. #LEAPstudy & #EATstudy meta-analysis demonstrates that early introduction of peanut prevents allergy in infants with mild & no eczema @GoAllergy
https://t.co/iAzOe9QcQN
George Du Toit: study shows “sadly only specific to peanut - but for peanut it works ” @GoAllergy talking #Leapstudy #IFAAA2019 @FoodAllergy meeting
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