Top Tweets for #LiquidBx
It was an honor to present on #MRD and liquid biopsy in Lung Cancer at the Ottawa Thoracic Symposium and a chance to spend time with a phenomenal leader in #LiquidBx Dr. Natasha Leighl! @isliquidbiopsy
Thank you @pwheatleyprice for the invitation, and congrats on a terrific symposium! @uOttawa @pmcancercentre
@ElizSMcKenna #newPI from @NIH to start the Cancer Prevention & Tumor Evolution lab @Nemours! We are interested in discovering & validating #biomarkers in cancer predispositions (#EndNF) as well as using #liquidbx in clinical & preclinical models of #childhoodcancer for adaptive risk modeling
The @NIH has been amazing for me, but I’m excited for the next chapter: https://t.co/T64p5J215m R. Taylor Sundby: Excited to Open the Doors to My Own Lab at Nemours Children’s Hospital/Thomas Jefferson Medical School - OncoDaily #newPI #endNF1 #supportgold #liquidbx
#ASCO25 @ASCO #EarlyDetection #CancerScreening
#LiquidBx
Abs 100: Reflex blood-based methylated ctDNA multi-cancer early detection (MCED) test in people with obesity:
• 🔬 Overall sensitivity for correct tissue of origin (TOO): ~30%
• 🎯 High specificity: 99% & NPV 98.9%
• 💥 Promising PPV for obesity-related cancers:
- Hepatobiliary 100%
- Colorectal 87.5%
- Upper GI 81.8%
- Uterine 66.7%
- Pancreaticobiliary 17.6%
• 🩺 Detects early stage cancers with meaningful sensitivity
This innovative test fills a critical screening gap for obesity-associated cancers. Prospective validation ongoing.
This is huge!!!
Generous support from @ChildrensTumor and @curenfwithjack as we begin to move our NF1 #liquidbx #cfdna assay from research to the clinic.
@MayoRadOnc @MayoCancerCare @MayoClinic @MayoClinicPath
@WashUOncology @washumedicine
@NIHClinicalCntr @NIH @theNCI
Grateful to @ChildrensTumor and @curenfwithjack's generous support of our (@MayoClinic-@NIHClinicalCntr -@washumedicine) efforts to move our NF1 #liquidbx #cfdna assay from research to the clinic!
Read more: https://t.co/1xmixGi3jw @jack_shern @aadel_chaudhuri @AngelaHirbe
Grateful to @ChildrensTumor and @curenfwithjack's generous support of our (@MayoClinic-@NIHClinicalCntr -@washumedicine) efforts to move our NF1 #liquidbx #cfdna assay from research to the clinic!
Read more: https://t.co/1xmixGi3jw @jack_shern @aadel_chaudhuri @AngelaHirbe
To beat cancer, we must all join forces!
Very proud to be part of the #LiquidBX consortium, working with other innovative companies and research labs to push the boundaries of liquid biopsy technologies. Kudos to @ILInnovationAut for providing the funding to realize this vision.
We’re advancing cancer care in the next phase of the #LiquidBX consortium. With funding from @ILInnovationAut, we're developing biomarkers for treatment response, leveraging omics data from over 1,000 solid cancer cases.
Details in WebWire: https://t.co/n4rHmUStMG
We’re advancing cancer care in the next phase of the #LiquidBX consortium. With funding from @ILInnovationAut, we're developing biomarkers for treatment response, leveraging omics data from over 1,000 solid cancer cases.
Details in WebWire: https://t.co/n4rHmUStMG
19/ In summary, our #liquidbx methods pioneer a platform to both (1) improve outcomes and (2) decentralize aspects of prevention. This would ⬇️ the burden of care in cancer predispositions that, like NF1, require lifelong surveillance.
1/ Can #liquidbx detect pre-malignancy & guide intervention to avert cancer before it develops? Our recent @NCIResearchCtr -@MayoClinic-@washumedicine led collaboration’s @CCR_AACR publication (https://t.co/M8zW6EOQbg) suggests that it can in #neurofibromatosis (NF1). A 🧵:
It was a huge privilege to co-lead the #liquidbx team with @PughLab. There are immense scientific + clinical opportunities w/ motivated multi-disciplinary teams working on them. I have no doubt that huge strides will be made in #NF1 care through #collaboration & #openscience!
And, of course, a very special thanks to @ChildrensTumor for supporting the circulating proteomic #liquidbx part of the story! Great colleagues and allies towards the common goal to #endNF
A star studded #liquidbx conference organized by @PughLab, @aadel_chaudhuri, @BrunaPellini, @NCIResearchCtr’s Adam Sowalsky/Sean Agbor-Enoch and others! Excited & intimated to present early #NF1 circulating #proteomic data tomorrow @ 11!
@NIH liquid biopsy conference in Bethesda starting off strong with keynote address by the one & only Dennis Lo!
In @ASCO’s Daily News our @NCI_CCR_PedOnc-@WUSTLmed -@MayoClinic #collaboration discuss the transformative potential for #cfDNA #liquidbx in hereditary cancer syndrome surveillance. We highlight strives by @landau_lab, @PughLab and others towards this 🥅
https://t.co/PWzgObMnlW
Thrilled to be invited to speak at the 7th Hellenic Conference of Oncology @myESMO. Looking forward to a great meeting with @g_mountzios, @marilykmd and many more.
@GreekOncol #LiquidBx @isliquidbiopsy
ctDNA Tumor Fraction continue to accumulate data as biomarker. The safir 2 study from @BenjaminBesseMD and group shown this in Durvalumab, with survival outcomes. #liquidbiopsy @isliquidbiopsy #ASCO23
#ASCO23 @ASCO
Integrating #LiquidBx Into Patient Care and Clinical Trial Design
Mon, Jun 5, 445CDT
https://t.co/LHzgeyl4Y8
@lillian_siu @geoff_oxnard @ChristianRolfo @drgandara
#ASCO23 Abs#9076
Utility of ctDNA TF in case of negative LBx rin #NSCLC
Important implications for use of ctDNA:
Elevated TF (≥1%) = High NPV
Negative LBx with low TF ( < 1%) should reflex to TBx
#LiquidBx
@ChristianRolfo @geoff_oxnard
@Oncoalert @ASCO @HemOncToday @ASCOPost
MPNST #sarcoma is the #1 cause of mortality in #NF1. Early detection and accurate dx of pre-malignant atypical NF is critical to improve outcome. Excited that our @WUSTLmed @NCI_CCR_PedOnc #liquidbx collaboration will have two platform talks @ChildrensTumor mtg re: early dx
Fantastic work on longitudinal #ctDNA monitoring in #SmallCell Lung Cancer 👏
#LiquidBx @ValsamoA @christine_lovly @WadeIams @SusanScottMD
What is the clinical utility of #liquidbiopsies and longitudinal #ctDNA monitoring in small cell #lungcancer? Read the latest from @HopkinsThoracic @MolecularOncLab just published in @CCR_AACR concurrently with our #AACR23 presentation
https://t.co/ErC3zYou3x
@hopkinskimmel @AACR
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