Top Tweets for #LoopExtrusion
https://t.co/pdJlbc6sjs We are glad to see further evidence confirming our finding that loop extrusion is dispensible for the spread of gH2AX (doi: 10.1016/j.isci.2024.110826). #loopextrusion #cohesin #dnarepair #DDR #DSB
If you are curious whether loop extrusion is required for γH2AX spread and MDC1 recruitment, you can have a look at the most recently published work from our lab out now in iScience #dnarepair #ATM #MDC1 #γH2AX #DDR #loopextrusion #cohesin
https://t.co/os9tFT7Dvt
Delighted to see our work https://t.co/jawirY5X5R from the Canzio lab @UCSF on how #cohesin-mediated enhancer-promoter interactions shape stochastic #Protocadherin choice profiles out @ScienceMagazine. #epigenetics #chromatin #DNAmethylation #LoopExtrusion #CTCF #3Dgenome. (1/8)
First paper from @fconforto1!
He burned through millions of CPUh on our supercomputer to answer "how does #loopextrusion affect the #viscoelasticity entangled polymers?"
Read more in his thread 👇
@golobor
@leonidmirny
@Anders_S_Hansen
@cees_dekker
@job_dekker
Hey everyone! I’m excited to finally share the result of our research on the effect of intrachain loop extrusion in entangled systems, now in https://t.co/KN25bWKgAi.
A thread
#Cohesin can resolve sister #chromatids already in G2 independent of #condensin - DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different #SMC protein complexes
@pauldanielbatty et al @Gerlich_Lab @IMBA_Vienna
https://t.co/vKDhwmZtXb
New collaborative project now on bioRxiv, getting to the bottom of the links between chromatin mobility, #transcription control and #loopextrusion processes
https://t.co/Uxlkvx7Wpi
@mitchell_lab @tinekelenstra @EviSoutoglou @molina_lab @AkisPapantonis @kerstinbys
Proud of this collaboration, getting to the bottom of the links between chromatin mobility, #transcription control and #loopextrusion processes, now on bioRxiv:
https://t.co/qiiz7NYAPZ
1/8
@mitchell_lab @tinekelenstra @EviSoutoglou @molina_lab @AkisPapantonis @kerstinbys
Our paper on #3dgenome structure at #mitosis is finally out in cell reports. We develop a theory that shows; how many #condensin proteins come together to form the mitotic #chromosome by #loopextrusion. 🧵(1/8)
Structural changes in chromosomes driven by multiple condensin motors during mitosis https://t.co/PZE3hIEgfg
Congratulations 🎉 to the #LymphocyteDevelopment team on their new publication, ‘Chromatin jets define the properties of cohesin-driven in vivo loop extrusion’
The findings shed new light on cohesin-mediated #loopextrusion
Click here to read more 👇
https://t.co/FJTngYDZpS
Researchers @MattiaConte94 @MarioNicodemi combine polymer models of loop extrusion and phase separation to best fit 3D genome data, and propose these two processes can coexist simultaneously in cells. #loopextrusion #phase-separation #singlemolecule
https://t.co/sqz5K5Mk0a
Researchers at #SunYatSenUniversity & @PKU1898 show that, different from the canonical #LoopExtrusion model, RYBP-mediated phase separation of #CTCF organizes inter-A compartment interactions.
https://t.co/qbCdaYXBYX
#ChromatinStructure #Pluripotency #CellBiology #ChinaResearch
Hello #AcademicTwitter and #3dgenome I have a new pre-print out on how #loopextrusion by multiple #condensin motors can explain #mitotic #chromosome structure. So let’s get to it, (a 🧵1/12)
An #Igh novel enhancer modulates antigen receptor diversity by determining locus conformation
#ChromatinConformation
#LoopExtrusion
#AntibodyDiversity
#BCells
V(D)J recombination
#AcademicTwitter @AcademicChatter @OpenAcademics
An Igh novel enhancer modulates antigen receptor diversity by determining locus conformation https://t.co/RHEFMIrp5x #bioRxiv
#3DGenome #dnarepair #loopextrusion #cohesin
Loop extrusion as a mechanism for formation of DNA damage repair foci | Nature https://t.co/i5qaOTL80p
The final version of our latest paper is finally out in the current issue of @ScienceMagazine🤩https://t.co/uspnOcgyxq Now you can also download the full supplementary! #cohesin #loopextrusion #TADs #dynamics
Jan-Michael Peters has an opening in his lab as part of our VIP2 postdoctoral fellowship program. Check out our website for further details: https://t.co/ZZwVsxe9UF @ERC_Research
@IMPvienna @IMBA_Vienna @gmivienna @MaxPerutzLabs #GenomeArchitecture #LoopExtrusion #Cohesin
Jan-Michael Peters has an opening in his lab as part of our VIP2 postdoctoral fellowship program. Check out our website for further details: https://t.co/uet1iLXIXc @ERC_Research
@IMPvienna @IMBA_Vienna @gmivienna @MaxPerutzLabs #GenomeArchitecture #LoopExtrusion #Cohesin
The Peters lab @IMPvienna is offering a position in the current call of the Vienna BioCenter PhD Program. Check our website for more information on Jan's research. #GenomeArchitecture #LoopExtrusion #Cohesin #CTCF
https://t.co/xcjEgDzBq0
@univienna @MedUni_Wien
The Peters lab @IMPvienna is offering a position in the current call of the Vienna BioCenter PhD Program. Check our website for more information on Jan's research. #GenomeArchitecture #LoopExtrusion #Cohesin #CTCF
https://t.co/TjdAPUBkGR
@univienna @MedUni_Wien
Here we describe a "walkthrough" to design and interpret SRLCI experiments, discussing both strengths and limitations! 3/n #chromatin #microscopy #superresolutionmicroscopy #loopextrusion #enhancerpromoterinteractions
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