Top Tweets for #NeuroAIDS
Nově publikovaná studie o #NeuroAids na @jclinicalinvest! Narušení dohledu T-buněk v mozku během počáteční virové infekce vyvolává chronický neurozánět a smrt neuronů.👇
Paper Alert! 🚨 Our newly published paper about #NeuroAids is out at @jclinicalinvest! Disruption of T-cell surveillance in the brain during initial viral infection induces chronic neuroinflammation and neuronal death.
Surprising no one, HIV is also a virus that infects the brain. But unlike SARS-Cov-2, it does not preferentially infect neurons but prefers to infect microglia, the brain's immune cells. Also, unlike SARS-Cov-2 (where the same virus infects both monkeys and humans), HIV is a mutation from the SIV (simian immunodeficiency virus), but both viruses are genetically very similar.
After entering the brain, HIV/SIV can infect microglia cells, where chronically "hide" inside the brain for years, or even decades, without being detected. This process often leads to chronic inflammation in the brain, commonly associated with HIV-associated cognitive decline (#HAND), observed even in very young patients.
Hiding inside the brain, HIV/SIV is not detected in any routine blood or saliva exam, and low levels of viremia in these places can falsely signalize recovery or a negative result. In fact, the virus can even mutate inside the brain, and the circulating virus in the blood can be a different strain than the one observed in the brain. Currently, no treatments are available to target this specific type of infected population.
The photo below shows microglia (🟠Iba1) carrying HIV/SIV (🟢 viral nucleocapsid protein) while "suspiciously" interacting with a surrounding neuron (🔵NeuN). Nuclei of cells in Dapi (🩷). #HIV #neurovirology #AIDS
#FluorescenceFriday
Paper: https://t.co/D5HGqhngbI
The doc is in! Dr. Hector Rodriguez is a distinguished psychiatrist and expert in the field of mental health disorders. 🧠 #SPECTscan #NeuroAIDS #HFR @doctorhector5
Check out our insightful interview with Dr. Hector Rodriguez!
https://t.co/zarZjozvn2
*Tenure track job alert* 👀 strong applicants working at the interface of #HIV and #cancer, #cardiovascular disease, #NeuroAIDS, or behavioral aspects of health, care, or prevention. Must demonstrate commitment to promoting diversity and inclusive excellence.@ThirdCoastCFAR
@NorthwesternU is hiring! If you are from the following research areas: Cancer, Cardiovascular and Metabolic Health, and Brain, Mind and Behavior, be sure to apply by October 31st: https://t.co/9yhiFOxzsp #NIHFirst #MedTwitter #InclusiveExcellence @NUFeinbergMed @NorthwesternEng
Congrats to #pathology PhD grad @AniellaMurphy, of Dr. Joan W. Berman's lab, whose study characterizing the effects of #buprenorphine on mechanisms of #HIV neuropathogenesis was published in @FrontImmunol & is top story in @NIDA news! #neuroAIDS
Paper: https://t.co/C7bryK5kAg
Super impressive works in progress today by #pathology Y5 MD PhD candidate Vanessa Ruiz, MS, re: characterizing subsets of uninfected & HIV-infected CD14+CD16+ monocytes that contribute to neuropathogenesis. Vanessa's in the lab of Dr. Joan Berman. Bravo!
#cns #HIV #neuroAIDS
Joan W. Berman, PhD, professor of #pathology @EinsteinMed has received a 5-year, $2.1M #NIH grant to study the possible role of chemokines CXCR7 & CXCR4 in #HIV neurocognitive impairment (NCI). More at https://t.co/DsoUdinjTO
#NeuroAIDS #PathTwitter #mephanphetamine #Science
Our latest pub is out 🎉today in JINS🎉, discussing dimensions of early-life adversity and their effects on cognitive and psychological functions in people living with HIV. https://t.co/i7o8AbcYuq #NeuropsychTwitter #NeuroHIV #NeuroAIDS
Today at 11AM CST Prof Karn @CWRUSOM @cwru will speak on "Role of #HIV #Latency, #Inflammation and Cross-talk Between #Microglia & #Neurons in #NeuroAIDS as part of the 8th CHAIN Center Colloquium
@NIMH @UNMCCOM @UNMC_neurology @UNMC_HIV @HIVBrainBanks @GPIDeACTR
Today at 11AM CST Prof Karn @CWRUSOM @cwru
will speak on "Role of #HIV #Latency, #Inflammation and Cross-talk Between #Microglia & #Neurons in #NeuroAIDS as part of the 8th CHAIN Center Colloquium
@NIMH @UNMCCOM @UNMC_neurology @UNMC_HIV @HIVBrainBanks @GPIDeACTR
Today at 11AM CST Prof Karn @CWRUSOM @cwru will speak on "Role of #HIV #Latency, #Inflammation and Cross-talk Between #Microglia & #Neurons in #NeuroAIDS as part of the 8th CHAIN Center Colloquium @NIMH @UNMCCOM @UNMC_neurology @UNMC_HIV @HIVBrainBanks @GPIDeACTR
Prof Jonathan Karn @CWRUSOM @cwru will present his latest research on "Role of #HIV #Latency, #Inflammation and Cross-talk Between #Microglia & #Neurons in #NeuroAIDS as part of the 8th CHAIN Center Colloquium
@NIMH @UNMCCOM @UNMC_neurology @UNMC_HIV @HIVBrainBanks @GPIDeACTR
Prof Jonathan Karn @CWRUSOM @cwru will present his latest research on "Role of #HIV #Latency, #Inflammation and Cross-talk Between #Microglia & #Neurons in #NeuroAIDS as part of the 8th CHAIN Center Colloquium @NIMH @UNMCCOM @UNMC_neurology @UNMC_HIV @HIVBrainBanks @GPIDeACTR
Researchers from @DibrugarhUniv provided a comprehensive discussion on the utility of nose to brain delivery of #antiretroviral drugs in the treatment of #neuroAIDS. @SpringerBioChem @SpringerNature .
https://t.co/iG9TA75E9c
Como los trastornos motores (ppalmente marcha y coordinación) están presentes en 69% de una cohorte nacional de pacientes VIH+. #NeuroAIDS
Characteristics of Motor Dysfunction in Longstanding Human Immunodeficiency Virus https://t.co/4gaVuTpEyf
Congrats Dr. Rosiris Leon Rivera on brilliant defense of your PhD thesis today: Mechanisms of #CNSViralReservoir Formation & Reseeding by #HIV+ Mature #Monocytes: Potential Therapies for #NeuroAIDS in the #Antiretroviral Era. 👏👏👏💖🔬🩺🎉 #Pathology #MedEd
The first Thursday #CurrentEVent of #ISEV2020 is "Emerging Trends in EV Research in #HIV, #NeuroAIDS & Drug Abuse" and chaired by the incomparable Shilpa Buch @unmc @IsevOrg @IsevComms
The CHAIN @UNMC_HIV #Developmental_Core has announced it's #funding opportunity for #2020 https://t.co/z1Pbjw67G2 Research must fall into the Division of #AIDS #Research High Priority Areas https://t.co/Jo4pk7zb8f @unmc @UNMCCOM #unmcCHAIN #HIV #AIDS #neuroAIDS #Aging #brain
The CHAIN Development Core (@UNMC_HIV ; @NIMHgov ) under the leadership of Profs S. Buch (https://t.co/bI468LNlvX), H. Fox (https://t.co/mktcvnE6Kh) & S. Swindells (https://t.co/FyXFi24GRg) stimulates innovative #collaborative #science in #HIV #aging and #neuroAIDS #unmcCHAIN
Are you looking for a postdoctoral research fellowship or know someone who is? Great news, we're hiring! Join us! https://t.co/5fLArn10Ng #postdoc #research #neuroHIV #neuroAIDS #stressresearch #nntc #hivresearch #MRI @DrRiveraMindt @DrDesireeByrd @EKTBenn @april_thames
Are you looking for a postdoctoral research fellowship or know someone who is? Great news, we're hiring! Join us! https://t.co/5fLArn10Ng #postdoc #research #neuroHIV #neuroAIDS #stressresearch #nntc #hivresearch #MRI
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