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EaglesPerch360

@EaglesPerch360

2 days ago

#fascinating #RejuvNote

Avi Roy

@agingroy

3 days ago

We treat regeneration as a superpower that other animals, like salamanders, have and we don't. A 2025 study in @ScienceMagazine says it's still in us, just turned off. Punch a hole in a rabbit's ear, and it grows back, skin and cartilage included. Do the same to a mouse, or to you, and the hole stays. A team in Beijing traced the difference to one gene, Aldh1a2, which makes retinoic acid, the signal that tells a wound to rebuild instead of scar. Rabbits turn it on at the injury. Mice carry the same gene, but evolution broke the switches that activate it. So the team dropped one working rabbit switch into mice, and the mouse ears started closing their holes. Mice, not people. But the program never left our genome. Evolution turned it off, and in a mouse you can turn it back on.

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