Top Tweets for #SPINA_GD
#SPINA_GT, #SPINA_GD and Jostel's TSH index (#JTI or #TSHI) are predictors of survival in patients with #Takotsubo syndrome (#stress #cardiomyopathy), as recently demonstrated in the international GEIST registry.
https://t.co/uPgANDlYgF
https://t.co/giXWJ15wVR
#SPINA_Thyr may be useful for monitoring of #endocrine disruptors. #SPINA_GD correlates to paraben excretion, and #SPINA_GT is modified due to exposure to butylparaben. https://t.co/13bAIjidVk https://t.co/XmretRTrH8 #SPINA_Thyr
@MaryS58459511 @Bianco_Lab It is not only about TSH, it is about thyrotoxicosis. From a clinical perspective, it is both essential and difficult to identify the reason for thyrotoxicosis (exogenous, subacute thyroiditis or true hyperthyroidism). #SPINA_GD may be a helpful tool in the diagnostic repertoire.
With a cut-off value of about 28 nmol/s, total step-up #deiodinase activity (#SPINA_GD) may be used for differential diagnosis between exogenous (factitious) #thyrotoxicosis and true #hyperthyroidism.
https://t.co/nX2lKYLKzk
https://t.co/rxlBcKmgCh
Total step-up #deiodinase activity (#SPINA_GD) is upregulated in metabolic syndrome, as demonstrated by a strong correlation to the triglyceride-glucose index. https://t.co/c58MHq88BF https://t.co/co5lz4ZJiK
Yet another study shows that #SPINA_GD goes down under substitution therapy with levothyroxine, underscoring the role of the TSH-T3 feedforward control. https://t.co/8pogwKoMrU
In a prospective study including women with #euthyroid autoimmune #thyroiditis, treatment with #vitamin_D increased #SPINA_GT, and therapy with selenomethionine raised #SPINA_GD, in parallel to improved #sexual function and reduced #depressive symptoms. https://t.co/weOpNTe20P
@MaryS58459511 This complements our study, where we saw an inverse relationship between deiodinase activity (#SPINA_GD) and L-thyroxine dosage. Under monotherapy, increasing L-T4 dose in subjects with persisting hypothyroid symptoms can make the situation worse. https://t.co/Id3WE7aCzI
L-T4 dosage and L-T4 in terms of basal metabolic rate are significantly increased in persons with low #SPINA_GD, mirroring a potential disruption of step-up #deiodination due to monotherapy with #levothyroxine.
https://t.co/iNuhpnxj9Q
https://t.co/D6FEUWOVYI
Total #deiodinase activity (#SPINA_GD) correlates to bone mineral density and predicts the risk for #osteoporosis. https://t.co/nEuzNfBqX4 https://t.co/E6xcMigFjA
Both #SPINA_GT and #SPINA_GD correlate with multiple #biomarkerโs for #cardiovascular_risk. https://t.co/2CRncltedq https://t.co/6tqO5ZsLk2
Immunotherapy, e.g. with immune checkpoint inhibitors (ICIs) is an increasingly used form of adjuvant cancer treatment. It may have, however, endocrine side effects. This study found deiodinase activity (#SPINA_GD) to be affected in subjects receiving ICI. https://t.co/8EXMUyiZaV
Results of the METAL study: #SPINA_GT and #SPINA_GD as well as calculated biomarkers for the central setpoint of #thyroid #homeostasis correlate to bone turnover markers in a large study including subjects with type 2 #diabetes. https://t.co/HGESOqbdfT https://t.co/cudV0E2oDQ
Therapy of #schizophrenia with the atypical antipsychotic agent #quetiapine affects #thyroid function in a complex way, including a reduced central set point, decreased #SPINA_GT and elevated #SPINA_GD. https://t.co/WZIuBw8YF3 https://t.co/dWW4j6EB9u
Complex effects of #endocrine #disruptors: In type 2 #diabetes, #SPINA_GT and #SPINA_GD are positively associated with urinary #phthalate excretion, depending on #autoimmunity and therapy with #metformin. https://t.co/ZiaR4YRS3u https://t.co/HVS4geuZuR
@dr_pmueller @EHRAPresident @GuerraCardio @RodrigueGarcia4 @Dominik_Linz @DavidDuncker @KommataVarvara @SteffelJ @EmmaSvennberg @Kasia_Rajpold @EPDeneke @C_Meyer_MD @Phiso_de @escardio @BobWeijs @pcw_EP @alexbejimd Although the time scale is different, allostatic modes of #thyroid homeostasis (#TACITUS_syndrome) should be considered as potential risk indicators as well. Low free T3 and #SPINA_GD, and high 3,5-T3 predict #POAF. @dr_pmueller
https://t.co/pC4CG1EheG https://t.co/ayAbMgt3zY
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