#Sarcomeric - Twitter Hashtag

about 1 year ago

14a) The most common #sarcomeric mutations induce #hypercontractility of the myofilaments & induces #diastolic dysfunction. This requires ⬆️ energy from the #mitochondria & drains NADH towards ATP production, at the cost of antioxidative capacity.

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Joel Salazar-Mendiguchía @JoelSMG

about 2 years ago

Disappointed to see the conservative approach to #genetic testing, recommending only the main #sarcomeric #genes. This ignores the recent evidence around FHOD3, CSRP3, TRIM63, ALPK3, etc. Also, phenocopies are not easily distinguishable and should be included from start, IMO.

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Circulation Research @CircRes

over 2 years ago

@CircRes Feb 2nd Issue is Out! https://t.co/IiX6g6rOKd Cover: Knockdown of the TF #SP1 leads to cardiomyocyte #hypertrophy of a #hiPSC-CM accompanied by intracellular #myofibrillar disarray (red) and #sarcomeric disorder (green); nuclei-blue.

CircRes's tweet photo. @CircRes Feb 2nd Issue is Out! https://t.co/IiX6g6rOKd

Cover: Knockdown of the TF #SP1 leads to cardiomyocyte #hypertrophy of a #hiPSC-CM accompanied by intracellular #myofibrillar disarray (red) and #sarcomeric disorder (green); nuclei-blue. https://t.co/8HaIaz31Qw

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cardio-met

@cardiomet_CE

about 3 years ago

35) It seems we have entered a new era of #HCM management with the development of #sarcomeric contractile inhibitors and approval of the first such agent, #mavacamten.

cardiomet_CE's tweet photo. 35) It seems we have entered a new era of #HCM management with the development of #sarcomeric contractile inhibitors and approval of the first such agent, #mavacamten. https://t.co/FkjSaa8XEn

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cardio-met

@cardiomet_CE

over 3 years ago

24d) Still, #genetic screening 🧬is key because even w/out symptoms, offspring members who inherit a #sarcomeric mutation must be followed up over time.

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Joel Salazar-Mendiguchía @JoelSMG

about 4 years ago

Signal-to-Noise Analysis Can Inform the Likelihood That Incidentally Identified Variants in #Sarcomeric Genes Are Associated with Pediatric #cardiomyopathy #genetics #cardiogen

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RegnierLab @LabRegnier

almost 6 years ago

Kudos to @FMoussaviHarami and team @J_Powers_ @JD98119 @MichaelRegnier9 for pioneering work showing modulation of the tension time integral combining computational and experimental methods to mitigate the remodeling in the heart with #sarcomeric #mutation! @UWISCRM @UWMedicine

LabRegnier's tweet photo. Kudos to @FMoussaviHarami and team @J_Powers_ @JD98119 @MichaelRegnier9 for pioneering work showing modulation of the tension time integral combining computational and experimental methods to mitigate the remodeling in the heart with #sarcomeric #mutation! @UWISCRM @UWMedicine https://t.co/Wqk7aLCDdg

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Giuseppe Limongelli @glimongelli

almost 6 years ago

Unexplained HCM in adults: not just #sarcomeric, #fabry, #amyloid. Look for #redflags to find #noonan, screen the family to find #noonan & #sarcomeric

glimongelli's tweet photo. Unexplained HCM in adults: not just #sarcomeric, #fabry, #amyloid. Look for #redflags to find #noonan, screen the family to find #noonan & #sarcomeric https://t.co/vv5POLp3kd

Emanuele Monda @MondaEmanuele

almost 6 years ago · Taranto

Combined PTPN11 and MYBPC3 Gene Mutations in an Adult Patient with Noonan Syndrome and Hypertrophic Cardiomyopathy, a rare association! https://t.co/sAFV0BxS31 @glimongelli

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Circulation Research @CircRes

almost 6 years ago

Moderated Poster Session 1A #Sarcomeric Function & #Contractility and 1B #Ion Channels and #Arrhythmias are under way. Support #EC investigators #BCVS20 @AHAMeetings @AHAScience @AHAScience

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AHAMeetings @AHAMeetings

about 7 years ago

Program and Registration for #BCVS19 https://t.co/tdIumskTPo #CardiacRemodeling #Sarcomeric #CardiovascularBiology #epigenetic #transcriptionalregulation #EpigeneticRegulation #GeneExpression #Cardiotwitter #basicresearch #CVresearch @aklfahed @ChristaTrex

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AHAMeetings @AHAMeetings

about 7 years ago

Program and Registration for #BCVS19 https://t.co/XPLyTV6BTv #Sarcomeric #CardiovascularBiology #epigenetic #transcriptionalregulation #EpigeneticRegulation #GeneExpression #Cardiotwitter #basicresearch #CVresearch

AHAMeetings's tweet photo. Program and Registration for #BCVS19 https://t.co/XPLyTV6BTv

#Sarcomeric #CardiovascularBiology #epigenetic #transcriptionalregulation #EpigeneticRegulation #GeneExpression #Cardiotwitter #basicresearch #CVresearch https://t.co/3PZ5WXWBu5

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AHAMeetings @AHAMeetings

over 7 years ago

Start preparing #BCVS19 #abstractsubmission and awards close March 13th! https://t.co/hfgR0ey9oD #Sarcomeric #CardiovascularBiology #epigenetic #transcriptionalregulation #EpigeneticRegulation #GeneExpression #Cardiotwitter #basicresearch #Genomics #CellularModels #Genetics

AHAMeetings's tweet photo. Start preparing #BCVS19 #abstractsubmission and awards close March 13th! https://t.co/hfgR0ey9oD #Sarcomeric #CardiovascularBiology #epigenetic #transcriptionalregulation #EpigeneticRegulation #GeneExpression #Cardiotwitter #basicresearch #Genomics #CellularModels #Genetics https://t.co/18EkuxV054

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Ernest Heimsath @Ernopodia

over 7 years ago

#Sarcomeric clouds. I guess there's a high level of #Myosin-II in the atmosphere at the moment.

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BRIC-inStem

@DBT_inStem

over 8 years ago

Dr Minhaj Sirajuddin from the Centre for Cardiovascular Biology & Disease, inStem begins his talk on understanding the role of #sarcomeric #protein biology and its implications in #cardiomyopathy. - inStem Annual Review

DBT_inStem's tweet photo. Dr Minhaj Sirajuddin from the Centre for Cardiovascular Biology & Disease, inStem begins his talk on understanding the role of #sarcomeric #protein biology and its implications in #cardiomyopathy. - inStem Annual Review https://t.co/y9rmyxmcOo

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