Top Tweets for #Targetome
#Targetome
Celastrol ameliorates cholestatic liver injury by inhibiting CTSS and restoring autophagy, shifting iNKT cells from pathogenic iNKT17 to protective iNKT1 polarization.
@FDA_Drug_Info @EUDrugsAgency #DrugDiscovery #Pharmacology
Details: https://t.co/CjDMNjvGwi
#Targetome
Crocin II triggers ANGPTL8 degradation via autophagy, reversing fatty liver disease! Natural saffron compound offers safe MASLD therapy breakthrough.
@FDA_Drug_Info @DetroitNeurons #masld #saffron #liverdisease
Details: https://t.co/AD32Z9F2e0
#Targetome
Acteoside targets CMPK2 to stop liver injury at its source! Multi-pronged protection against mitochondrial damage in hepatic ischemia-reperfusion.
@FDA_Drug_Info @DetroitNeurons #liverinjury #damage #protection
Details: https://t.co/iKJveCGuan
#Targetome
AI-designed evodiamine derivative 8a targets gp130, halting tumor growth by 56%! Novel indolopyridine offers promising colorectal cancer therapy breakthrough.
@FDA_Drug_Info @DetroitNeurons #cancertherapy #tumor #therapy
Details: https://t.co/t4E9AyMo23
#Targetome
Review summarizes decade of advances in natural product target identification, highlighting chemicobiological and computational methodologies for NP-based drug development.
@FDA_Drug_Info @PKU1898 #TargetIdentification #DrugDiscovery
Detail: https://t.co/ih0cExZWEf
#Targetome
Single-cell & spatial omics + AI are revolutionizing how we understand traditional Chinese medicine's holistic effects at the cellular level.
@FDA_Drug_Info @DetroitNeurons @ZJU_China #single #cellularlevel #omics #effect
Details: https://t.co/iEg4RYgFMs
#Targetome
AI is revolutionizing traditional Chinese medicine by decoding chemicalomes, targetomes, and bioactivomes—bridging ancient wisdom with cutting-edge science!
@FDA_Drug_Info @DetroitNeurons #cuttingedge #wisdom #science
Details: https://t.co/7RLLFkVBLb
#Targetome
Xuebijing injection shows promise for acute lung injury by protecting alveolar barriers and reducing inflammation through multiple cellular targets.
@FDA_Drug_Info @DetroitNeurons #injection #injury #inflammation #lung
Details: https://t.co/ROqrDzObgQ
#Targetome
SETD2 emerges as a chromatin regulator of iron metabolism, controlling IRP2 levels and ferroptosis sensitivity through epigenetic mechanisms.⚙️
@FDA_Drug_Info @DetroitNeurons #ironaddict #details #metabolism
Details: https://t.co/vBhF0jt2nQ
#Targetome
Zinc supplementation reduces COVID-19 mortality by half, with MT2A emerging as a key biomarker for metal stress and immune response 🦠⚡
#immuneresponse #metal #stress #zincsupplementation
Details: https://t.co/05CErGbo9l
#Targetome
New study in Nature Neuroscience reveals Fc effector function is crucial for lecanemab's amyloid clearance in Alzheimer's treatment.🧠✨
#alzheimer #naturelovers #neuroscience #effector
Details: https://t.co/b6zW63C3SX
#Targetome
Mining TTD uncovers understudied target pairs ripe for combo therapy—data-driven map guides cheaper, smarter multi-drug shots.
@FDA_Drug_Info @DetroitNeurons #ttd #therapy #target
Details: https://t.co/nNxCuA733k
#Targetome
Targeting neddylation shows promise for metabolic disease treatment. Fine-tuning cullin 3 activity key for safe, effective therapies. 🔬💊
@FDA_Drug_Info @DetroitNeurons #metabolicdisease #promise #therapy #targeting
Details: https://t.co/2dZiANZLtI
#Targetome
iNKT cells uniquely bridge innate/adaptive immunity via CD1d/glycolipid recognition, offering promising off-the-shelf therapy for cancer/infections with low GVHD risk! 🧬💉
#recognition #therapy #infections
Details: https://t.co/sqc9TZm4NK
#Targetome
INKT cells uniquely bridge innate/adaptive immunity via CD1d/glycolipid recognition, offering promising off-the-shelf therapy for cancer/infections with low GVHD risk! 🧬💉
@FDA_Drug_Info @EUDrugsAgency #recognition #therapy #infections
Details: https://t.co/aJ0a4kxdqc
#Targetome
Two decades on, RNA has graduated from messenger to medicine, revolutionizing how we drug the undruggable. 🧬✨
@FDA_Drug_Info @EUDrugsAgency #decades #rna #medicine
Details: https://t.co/nz5BfY0hOZ
#Targetome
Ceramides predict heart risk solo; Zhang finds they hijack CYSLTR2/P2RY6, sparking plaque. Block the duo, cut inflammation, ignore lipids. 🫀🎯
@NeuronsInc @DetroitNeurons #risk #inflammation #block
Details: https://t.co/djd8bpyvRJ
#Targetome
Silybin + carvedilol combo shows powerful synergistic effects against liver fibrosis by inhibiting Wnt4/β-catenin signaling in activated hepatic stellate cells! 🧬💊
@NeuronsInc @EUDrugsAgency #liverfibrosis #effect #combo
Details: https://t.co/IvkUTwHnaf
#Targetome
Alzheimer’s fails single-target fixes; letrozole-irinotecan duo rewires neurons, erasing mouse plaques. Cell study lights combo-therapy path. 🧠🔥
@NeuronsInc @DetroitNeurons #singletarget #alzheimer #target #therapy
Details: https://t.co/1wl6O4dIUl
#Targetome
RNA drugs rewrite disease genes 💉 yet stability & delivery hurdles persist; nano-carriers & circRNA spark next-gen cures 🧬
@FDA_Drug_Info @EUDrugsAgency #nextgen #drugs #genes #stability
Details: https://t.co/pWXMFj3CeI
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