Top Tweets for #ThresholdMatters
📢#Serotonin acts as a #Sword & a #Shield in the #Gut 🎯Play both #offense & #defense‼️
▶️It’s critical for #health when & to what extent “#silence or #enhance” #Enterochromaffincell/#Serotonin signaling 🙌
#ThresholdMatters #GutPain #DGBI #IBS #IBD
👉https://t.co/hVuGo9QAEH
👉https://t.co/lpONQKhT2J
👉https://t.co/bt7bpHSGEW
👉https://t.co/egubxmRe7a
👉https://t.co/UIm0hWrY0H
👉https://t.co/69Ezfzl48r
@AmerGastroAssn @AmCollegeGastro @my_ueg @ANMSociety @esnm_eu @INMAssociation @anma_i @ANGMA_AU @RomeGastroPsych @GutBrainScience @APSPhysiology @NYUPainResearch @GMFHx @NatRevGastroHep @NGMJournal @ajpgi @JNMjournal
🧵Revisiting #Enterochromaffin (EC) cells & #GutSerotonin, as a sword and shield of the bowel, play both #offense & #defense
Recent published study in @Nature showed EC drive #VisceraPain & #Anxiety and No Impact on #GITransitTimes @md_jrb @DJ@md_jrb @DJuliusSF 👏
👉This study challenges the prevailing belief that #ECcells & #GutSerotonin drive #GutMotility. What do you think? #GITwitter #MedTwitter #ScienceTwitter

✅#Serotonin acts as a #Sword & a #Shield in the #Gut
▶️It’s critical for #health when & to what extent “silence or enhance” EC cell/Serotonin signaling #ThresholdMatters
@NatRev@NatRevGastroHep @AmerGastroAssn @AmCollegeGastro @my_ueg
https://t.co/QXseC0eedm
https://t.co/pJhEa8e0iP
I am pleased to share our paper discussing the most recent discoveries on Enterochromaffin Cells–Gut Microbiota Crosstalk: Underpinning Symptoms, Pathogenesis & Pharmacotherapy in #DGBIs
https://t.co/IHkcuuvg7n
@LaiWeiLisa @Rajan___Singh Prof. Uday Ghoshal
#Serotonin #GITwitter

Fascinating study on #SIBO @AGA_CGH
Prof. @MarkPimentelMD & Colleagues👏
🔥Dive deep into #Composition #Diversity #Functional relevance of #DuodenalMicrobiome in context of #GISymptoms
➡️#ThresholdMatters for defining SIBO
✅ ≥10³ CFU/mL on #MacConkey is associated with⬇️ #DuodenalMicrobial diversity, ⬆️Relative Abundance of Escherichia/Shigella & Klebsiella, & disruptions in #MicrobialNetworks ➡️#KeyMicrobial tipping point for the development of GI symptoms #AbdominalPain #Diarrhea #Bloating
#DoubleLumenCatheter #ShotgunSequencing #GutMicrobiome #GITwitter @GutBrainScience

As promised. Herculean effort by our @MASTprogram and @GabrielaGSLeite to technically define #SIBO. We define the bugs, cutoff, correct media to find SIBO, the right catheter to use, and symptoms! This paper sets stage for treatment. #microbiome @AGA_CGH https://t.co/UPbGqfVhkh
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