James Bayrer

Gastroenterologist and physician scientist | New Cow Punk fan

[James Bayrer @md_jrb]

Happy to share our lab's newest preprint. Congratulations to Hsi-Ju for all the work spearheading this project!

Nuclear Receptor Liver Receptor Homolog-1 drives Intestinal Stem Cell regeneration and UPR/ER stress response after gut injury https://t.co/wloOFQu9dR

[James Bayrer @md_jrb]

Funding cuts are threatening our ability to work towards a better future for vulnerable kids, and I would be incredibly thankful for any support!

https://t.co/6zpbRhNBJt

[James Bayrer @md_jrb]

I'm running a 5K to raise money for pediatric Gl research and soliciting donations.
I spend my days caring for kids with serious GI diseases and researching how to improve their health.

1/2

[James Bayrer @md_jrb]

Congratulations to @CallieGood86628 for her outstanding talk at #ANMS2025

[James Bayrer @md_jrb]

@vandoliers Wait, one for $5 or two for $11? They charge more if you like it enough for a double?

[James Bayrer @md_jrb]

Looking forward to catching up with friends and colleagues at #ANMS2025

[James Bayrer @md_jrb]

Outstanding write-up in @RollingStone on Jenni Rose and the @vandoliers! Looking forward to their new album and concert in July! https://t.co/KZ45IFem0p

[James Bayrer @md_jrb]

Great work Kara, congrats!

[kara gross margolis @karagm2009]

Our true labor of love was published at Gastroenterology!! We showed: increased risk for the DGBI, functional constipation-matching our findings in Molecular Psychiatry and( 2) the gut may be a more targeted way to treat anxiety and depression!
https://t.co/HzRkxzWvpg

[James Bayrer @md_jrb]

@vandoliers Menlo Park for us!

[James Bayrer @md_jrb]

Preparing to travel internationally across the international date line leaving on daylight savings changeover and trying to figure out how many pairs of socks to bring.

[James Bayrer @md_jrb]

@DougJBalloon Democracy dies in darkness indeed

[James Bayrer @md_jrb]

@KarlTheFog Personally, I find the Technicolor Fog effect kinda cool.

[James Bayrer @md_jrb]

@md_wallach Yet another thing we trained you for at UC San Francisco!

[James Bayrer @md_jrb]

Fantastic high level summary of the effort, challenges, and importance of your work at SAHMRI!

[Bench Side Story @BenchSideStory]

RESEARCHER PROFILE
Professor Stuart Brierley (Filmed February 2024)
Director of the Visceral Pain Research Group,
Director of the Hopwood Centre for Neurobiology &
Theme co-Leader of Lifelong Health
South Australian Health and Medical Research Institute (SAHMRI) @sahmriAU

Professor Stuart Brierley is Director of the Visceral Pain Research Group, Director of the Hopwood Centre for Neurobiology, and Theme co-Leader of Lifelong Health at the South Australian Health and Medical Research Institute (SAHMRI) @sahmriAU.

He has developed a strong track record in coordinating and working in multi-faceted research programs for high impact publications in journals. His work has attracted four NHMRC Fellowships including other @nhmrc and @NIH grants.

The global pandemic has shed light on the severity of the Opioid Crisis, highlighting the urgent need for effective pain treatments. During his 24 years as a researcher, Professor Brierley has made significant strides in understanding how pain arises from the gastrointestinal tract or the gut.

Prof Brierley is an international expert on the 'gut-brain axis' and chronic visceral pain mechanisms. Current investigations are on a individual cell type called the enterochromaffin cell, and it helps signal pain and anxiety from the gastrointestinal tract to the brain.

His research comprises discovery and translational science investigating the nerve pathways innervating visceral organs to determine the causes of, and treatments for, Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD), bladder pain syndrome, and endometriosis.

Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) disorders are highly prevalent, affecting up to 15% of the Western population.

Despite being a major global clinical issue, pain, especially from the gastrointestinal tract, lacks effective treatments, and the research focuses on understanding and treating pain in gastrointestinal diseases in order to develop targeted treatments. Individual gut cells communicate with the brain to signal pain and trigger symptoms that include depression and anxiety.

Professor Brierley is collaborating with researchers in Australia and internationally including Nobel Prize winner Nobel Prize Laureate Professor David Julius @DJuliusSF, Professor Holly Ingraham @hollyingrahamSF and Dr Jim Bayrer @md_jrb at the University of California San Francisco @UCSF, all with the goal of helping people.

His research interests extends into other common causes for visceral pain including interstitial cystitis/painful bladder syndrome and endometriosis and how ‘cross-organ sensitisation' can potentially explain co-morbidities in these patients.

Pain is a global issue, and Professor Brierley’s work aims to understand its causes in order to develop targeted treatments, while also balancing a busy family life and various interests.

SEE OTHER RESEARCHER PROFILES
Bench Side Story
https://t.co/vzQCTpFOVv

[James Bayrer @md_jrb]

@western_grunge Back in 2018

[James Bayrer @md_jrb]

Thanks @vandoliers for absolutely making Jake’s day!

[James Bayrer @md_jrb]

Congratulations!

[Homa Majd @homamajd]

Ever wondered how diverse bowel functions are controlled? The key lies in its incredible array of diverse enteric neurons. Our analysis reveals some important challenges in their annotations and calls for taking a holistic approach.
@FaranakFattahi
https://t.co/pfYLkgcCAd

[Faranak Fattahi @FaranakFattahi]

In our new preprint by @homamajd et al., we describe an extensive comparative analysis of several single cell transcriptomics datasets that underscores challenges in defining neuronal identity in the ENS. Huge thanks to all coauthors! @StampHaoLab @mghpedisurg

[James Bayrer @md_jrb]

I’m honored to be selected and looking forward to the meeting this May!

[SPR @SocPedResearch]

Congratulations to Dr. James Bayrer, our 2024 SPR New Member Outstanding Science Awardee! This award recognizes new members who have contributed to high quality scientific research & demonstrate meaningful contributions in the pediatric academic field. https://t.co/WWnPIIfHXp

[James Bayrer @md_jrb]

@md_wallach I’m afraid I’m not very good at it!