Top Tweets for #acmsd
Excited to share our new publication in JBC on the enol/keto tautomerization of oxaloacetate by ACMS decarboxylase (doi: 10.1016/j.jbc.2024.107878)! This finding highlights the need for further biological testing. #ACMSD #enzymology #Oxaloacetate #metabolism
Congratulations to UTSA Chemistry’s Yu Yung, Ian Davis, and Dr. Aimin Liu on their published article in the Journal of Biological Chemistry about “α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto...” Be sure to check it out! https://t.co/HVg75H9HLc

An enzyme in the kynurenine pathway that governs vulnerability to suicidal behavior by regulating excitotoxicity and neuroinflammation #ACMSD #rs2121337 #neopterin #MECFS #LongCovid
https://t.co/gXAjH0CqQV
@foundmyfitness "Pharmacological treatments are also being developed to boost NAD+ metabolism by stimulating NAMPT, inhibiting ACMSD & inhibiting NAD+-consuming enzymes."
https://t.co/7m7cRwHgvT
#Omega3 may stimulate #NAMPT, #PGC1a, #Sirtuins, downregulate #ACMSD & modulate NAD+ recycling via

The kynurenine pathway (aka tryptophan metabolism) is also implicated in #parkinsons disease, with #quinolinic acid being a neurotoxin and pro-inflammatory agent. @VAInstitute #ACMSD
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond - a new review https://t.co/1ulnCjAgTB

@gangulyteena @kadzuis @nature @mep_unil There is a new mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content:
https://t.co/lQSxo9HfN2
There also is a mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content now!
https://t.co/lQSxo9HfN2
@Auwerx_Lab identifies an endogenous pathway to boost #NAD+ levels in worms and mice by inhibiting the enzyme #ACMSD. Boosting #NAD+ levels via #ACMSD inhibition ameliorates #NAFLD and #AKI. #NatMetabPicks
https://t.co/9QwZmbYavt
@researchonaging @nature There is a mouse model (#ANDYmouse) using #ACMSD to change #NAD tissue content now!
https://t.co/lQSxo9HfN2
#ACMSD is important for dietary #niacin requirements, #NAD tissue content and aging. ANDY, the new #ACMSD #mouse can be used to modulate tissue #NAD content and should be great tool for #NADresearch in #aging, #health, #cancer, #DNArepair and #Epigenetics.
https://t.co/lQSxo9HfN2
Another potential #Omega3 #AntiAging mechanism:
https://t.co/8hMWGi9JIm
#ACMSD #NAD+ #SIRT1 #Mitochondria
https://t.co/560rEi5Ygr
@Auwerx_Lab identifies an endogenous pathway to boost #NAD+ levels in worms and mice by inhibiting the enzyme #ACMSD. Boosting #NAD+ levels via #ACMSD inhibition ameliorates #NAFLD and #AKI. #NatMetabPicks
https://t.co/9QwZmbYavt
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