Top Tweets for #beta_cells
Latest curated papers👇🏽
📷Replacement of #Beta_Cells for #Type_1_Diabetes
📰How #ageing changes our genes - huge #epigenetic atlas gives clearest picture yet
🤰🏽Regulatory KIR+CD8+ T cells in #pregnancy
🔗https://t.co/csz4apqKId
🙏🏽Thx @Bims_BiomedNews
#Diabetes mellitus is a medical condition that affects how your body processes #glucose (#sugar)
#type1diabetes: An autoimmune condition where the body's immune system attacks and destroys #insulin-producing #beta_cells in the pancreas.
#type2diabetes: In type 2 diabetes, the body becomes resistant to insulin, and the pancreas may not produce enough insulin to maintain normal blood sugar levels.
3. Gestational diabetes: Occurs during pregnancy when the body cannot produce enough insulin to meet increased demands.
#diagnosis
Fasting glucose level #FBS
Glucose level after 2 hours of meals #BSR
Oral glucose tolerance test #OGTT
Glycated hemoglobin #HbA1c
#C_peptide level
#Symptoms:
Increased thirst, frequent urination, unexplained weight_loss, and fatigue. Long-term #complications can include heart disease, kidney problems, nerve damage, and vision loss.
#Causes of diabetes mellitus
1. Type 1 Diabetes
#Autoimmune Response: The exact cause is not fully understood, but it's believed to involve a combination of genetic and environmental factors. The autoimmune system attacks and destroys insulin-producing beta cells in the #pancreas.
2. Type 2 Diabetes
#Insulin_Resistance: This type is strongly associated with #lifestyle factors. The primary causes include:
#Obesity: Excess body fat, particularly around the abdomen, is a significant risk factor.
Physical Inactivity: Lack of exercise can contribute to insulin resistance.
#Genetics: Family history can play a role; there is a genetic predisposition in some cases.
Poor #Diet: Consuming high amounts of processed foods, sugary beverages, and unhealthy fats.
3. Gestational Diabetes:
Hormonal changes during pregnancy can lead to insulin resistance. It typically resolves after childbirth.
Treatment
Type 1 Diabetes:
Insulin Therapy: People with type 1 diabetes must take insulin to replace the hormone their bodies no longer produce.
Diet and #exercise: A balanced diet and regular physical activity help manage blood sugar levels and overall health.
2. Type 2 Diabetes:
Lifestyle Modifications: It includes changes in diet and exercise to control blood sugar levels and promote weight loss, if necessary.
#Oral_Hypoglycemic_Agents: Some people with type 2 diabetes may be prescribed oral medications to help the body use insulin more effectively or to stimulate the pancreas to produce more insulin.
Injectable Medications: In some cases, injectable medications, including insulin, may be necessary to control blood sugar.
Blood Sugar #Monitoring: Regular monitoring is important to track how well the treatment plan is working in both types of diabetes mellitus.
3. Gestational Diabetes:
Diet and Exercise
Insulin &\or Oral Hypoglycemic Agents
Oral Hypoglycemic Agents:
1. #Biguanides (#Metformin): It works by reducing the production of glucose in the liver and improving the body's sensitivity to insulin. It doesn't typically cause low blood sugar (hypoglycemia) when used alone.
2. #Sulfonylureas (#Glipizide, #Gliclazide): These drugs stimulate the pancreas to produce more insulin. They can lead to hypoglycemia.
3. #Meglitinides (#Repaglinide, #Nateglinide): These drugs work by stimulating insulin release from the pancreas, but their effects are shorter-lived and are taken before meals.
4. #Thiazolidinediones (#Pioglitazone, #Rosiglitazone): Improve insulin sensitivity in the body's cells and reduce the amount of glucose produced by the liver.
5. Alpha-glucosidase inhibitors (#Acarbose, #Miglitol): These drugs slow down the digestion and absorption of carbohydrates, helping to reduce post-meal blood sugar spikes.
6. #Dipeptidyl Peptidase-4 (DPP-4) Inhibitors (#Sitagliptin, #Saxagliptin): Enhance the body's own ability to lower blood sugar levels by increasing the activity of incretin hormones.
7. Sodium-#Glucose_Transporter-2 Inhibitors (#Canagliflozin, #Dapagliflozin): Help the kidneys remove excess glucose from the bloodstream through urine.
Stop by to chat w/ Haiting Ma PhD (MIT/@JaenischLab) 10/14, 9am PT
#pyroptosis #beta_cells #synthetic_immune_system
@MIT @vumcdiabetes @IUSweetTweets @AtUcsf @SoleimanpourLab @UMICH @UMassDiabetes @ljiresearch @TheMeltonLab @ufdiabetes @ubclifesciences
https://t.co/mcMKSttAw5
#OPPS Feinstein Institutes Receives $1.3M NIH Bioelectronic Medicine Grant : Neuro-Immune Signaling. Q: could the case be made that pancreatic #beta_cells fall under the "neuro" category? |https://t.co/Y9aBz9UtMI
Join us for the 5⃣th #STATE_of_the_SCIENCE
THURSDAY JULY 29 @ 8-9am PDT//11am-12pm EDT
"#Mitochondrial and #Pro_Hormone Dysfunction in #Beta_Cells"
Linnemann-Gaulton-Soliemanpour-Wagner-Thompson-Atkinson
@ufdiabetes @IUSweetTweets @UMich @ucsdbiosciences @umanitobasci @MIT
MicroRNA Sequences Modulated by Beta Cell Lipid Metabolism: Implications for Type 2 Diabetes Mellitus https://t.co/10zJm42sNL ##mdpibiology via @Biology_MDPI @CaledonianNews
#microRNA #lipid #lipotoxicity #islets #beta_cells
Ask the expert: tomorrow May 18 from 2-2:30pm PDT.
New Ideas in Stem Cell Science....making #beta_cells
Short-Informative-Fun
@TheMeltonLab @HIRN_CC @SanRaffaeleDRI @Diabetes_DRI @AtUcsf @ucsdbe @ufdiabetes @UAlberta_DoM @CIRTNetwork @ubclifesciences @kochinstitute
#NMDA_R off #synchronizes #beta_cells
@GBioelectronics @guy_rutter @philippeblancou @ljiresearch @MABenkahla @MadinaMakhmuto1 @Diabetes_DRI @HecksherS
https://t.co/9uwiHIrIO0
Don't miss it!
the(sugar)science and DESIGNER IMMUNOLOGY are at talking about #senescence and #beta_cells
"https://t.co/KM3NnxIgkk
New podcast sneak peek: Robert Screaton joins us to discuss his work studying type 1 diabetes. He answers one big question: Can we get human #beta_cells to regenerate? @robert_screaton @UofT
TOMORROW! the(sugar)science is hosting Ask the Expert:@robert_screaton PhD, @BBDC_UofT @UofT @AtUcsf @ufdiabetes @TheMeltonLab
"Can we get adult human #beta_cells to regenerate?"
https://t.co/uruOr9pUxH
Our latest research on making better beta cells from human ESCs/iPSCs through CD9 selection
#stem_cells
#beta_cells
#cell_surface_marker
🌟 New in @stemcellreports
Dr. Kathy Lui and scientists from the Chinese University of Hong Kong (@CUHKofficial) purified β-like cells for spontaneous formation of islet-like #organoids against CD9.
https://t.co/ZW9R3SatZM
Researchers have discovered that one of the building blocks in the #calcium channels in the pancreatic #beta_cells play an important role in regulating our blood glucose values.
سيتم الحديث لاحقا إن شاء الله عن
#pancreas
#islets #langerhans
#insulin
#beta_cells
#amino_acids
#polypeptied_chains
#blood_glucose_level
44 (12-25): #Liver #protein boosts growth of #insulin-producing cells. #diabetes #pancreatic #beta_cells #islets #serpinB1
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