Delighted to share our latest now published in@NatureComms, where we found a new role for mitochondrial programming of SC-β cell fate through PPARα!
We're excited for the potential to target mitochondria to improve SC-islets to treat #T1D!
https://t.co/6zvVHxwkRt
🚨 New paper from our lab in BMC Methods!
We describe a simple, rapid, and cost-effective method to identify subcutaneously transplanted pancreatic human islet grafts using dithizone (DTZ) staining. #diabetes#stemcells#islets 🧵
https://t.co/wM7n2lAQM7
Congratulations to Chandel lab for demonstrating that a metabolite once considered purely “toxic” may actually be a key signaling molecule in cells and organisms. This study demonstrates that l-2-HG functions in signaling by regulating epigenetic state via KDM4/H3K9me3 demethylase and linking redox state to transcriptional repression. The study provides initial words in “Metabolic Language” of transcription. https://t.co/VGUTYlhsk3 @NU_BMG_SQE@NUFeinbergMed@Nature@CellPressNews@ScienceMagazine@MolecularCell@theNASciences@theNAMedicine@NorthwesternU@NatMetabolism
We are once again recruiting at all levels! See links for postdoc https://t.co/Yg53SJaNE0 and technician https://t.co/vNzSiRp6PH position ads. Read more about our research in our latest preprint https://t.co/L5WecRGrBq and on our website https://t.co/tXDcLI2HMU.
The fascinating biology of targeting nuclear receptor ligands to GLP-1 receptor + cells continues, with the latest chapter studying GLP-1 E2 in NOD mice, with or without low dose aCD3 @DiabetologiaJnl https://t.co/dwXNWmlNwL
Congratulations to Drs. @SoleimanpourLab and @adina_turcu, who were recently inducted into The @the_asci!
Learn more about the society and their research at https://t.co/NWWSjOcT8e.
The Crewe lab is looking for a postdoc to study adipose extracellular vesicle signaling in cardiovascular disease. Send me an email if you are interested!
Join us May 12 for the 2026 Saltiel Life Sciences Syposium: Decoding GLP-1s!
This full-day event will explore the fundamental cellular mechanisms behind the new generation of hashtag#GLP1 therapeutics, as well as ongoing efforts to improve them.
Speakers include @AmberAlhadeff, @DanielJDrucker, @TimoMueller_IDO, Martin Myers, @tunepers , @seeleyrj and @thewilliamslab
We mourn the passing of Gordon Weir, a towering figure in the field of diabetes, and valued colleague and friend of countless members of the @JoslinDiabetes and @Harvard diabetes communities. https://t.co/nRwqiUk8g9
At this link, you can watch the brilliant lecture by Helen Hobbs today on the topic: Genetic Disorders of Dietary Excess: Getting to the Heart of the Matter. An exquisite example of the power of medical research by a great physician-scientist. https://t.co/xrjnUWmhc8
Congratulations to Dr. @DanielJDrucker, a 2026 Governor General's Innovation Award laureate! 🏅
This award celebrates Canadians who improve lives through innovation & Dr. Drucker's GLP-1 & GLP-2 discoveries have done exactly that.
Learn more ➡️ https://t.co/XgjB2nWLV5
What a fun surprise to find that our work has been featured in a @JCellBiol spotlight!! Many thanks to Carlotta Peselj and Nora Vögtle for the great write up!
New website alert! We are transitioning to our dedicated site https://t.co/Ka7zPsekcI for weekly seminar announcements and communications. Thank you for your support as we retire this Twitter/X account. See you there!
The human alpha cell's competence to secrete glucagon depends on paracrine inhibitory input from beta (serotonin [5-HT], γ-aminobutyric acid [GABA]) and delta (somatostatin [SST]) cells #islets https://t.co/SF0UwvEqZG
High intensity interval training HIIT identified as a potent stimulus for improving muscle oxidative and metabolic health in type 2 #diabetes in part via expanding muscle mitochondrial cristae density https://t.co/DufGA7uCgE