Top Tweets for #celastrol
🔬 Our findings support multimodal MRI as a powerful non-invasive approach to monitor brain responses to anti-obesity therapies and improve our understanding of their mechanisms of action.
#Obesity #Neuroinflammation #MRI #Metabolism #Neuroscience #Research #Celastrol #Imaging
Article✍️#Celastrol-#loaded #ginsenoside #Rg3 #liposomes boost #immunotherapy by remodeling #obesity-related #immunosuppressive #tumor #microenvironment in #melanoma. From Dr. Xiong @ZhejiangChineseMedicalUniversity; @ELSpharma.
https://t.co/PhhaZJsDoK.
Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid #celastrol against chronic diseases Click the link below to read this #open_access article. #medtwitter https://t.co/2OqPJ2YTkh
Druggability, molecular targets, and nanocarrier delivery of natural triterpenoid #celastrol against chronic diseases Click the link below to read this #open_access article. #medtwitter https://t.co/2OqPJ2YTkh
Rao Yu's team applied a "Degradation-Based #Protein Profiling" strategy to uncover known and novel targets of #Celastrol, establishing the first glycosidase degrader to complement existing target identification strategies. #InnovativeTsinghua More: https://t.co/eay6Tj3PaA
How a #Natural Compound Tamps Down #Immunity & May Treat #Arthritis | Scientists revealed how a natural molecule called #celastrol, which has been used in traditional #ChineseMedicine, works to tamp down immunity. https://t.co/g5XjTqsVul
The Article from Suzuki Lab was published in Science Immunology
"Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex ”
https://t.co/IkjYPJy1Wm
#osakauniversity #RIMD #IFReC #autoimmunity #celastrol
Article✍️#Celastrol induces #ferroptosis in activated #HSCs to ameliorate hepatic #fibrosis via targeting peroxiredoxins and #HO-1. Using an array of chemical biology techniques, the direct target of celastrol &its mechanism are explored in liver fibrosis.
https://t.co/ZnE0TdgHHB
Article✍️#Celastrol enhances transcription factor EB (#TFEB)-mediated #autophagy and mitigates #Tau pathology: Implications for #Alzheimer's disease therapy. Celastrol, a TFEB activator, promotes degradation of p-Tau aggregates&improves memory deficiency.
https://t.co/jQsmRGf5Ep
🥈Check out our second most downloaded article (>3000 times)!
🔬Ferroptosis inducer erastin sensitizes NSCLC cells to celastrol through activation of the ROS–mitochondrial fission–mitophagy axis
👉https://t.co/R447qoFVbP
#Erastin #Celastrol #Mitophagy
Our latest research paper is now published on #ACSChemBiol. We used multiple mass-spectrometry-based approaches to identify catechol-O-methyltransferase #COMT as a major binding target of #Celastrol and characterized their interaction comprehensively.
https://t.co/8N43idurYd
#RecommendedPaper #InterestingPaper
Oral #Bioavailability Evaluation of Celastrol-Encapsulated Silk Fibroin Nanoparticles Using an Optimized #LC-MS/MS Method
By: Shuyu Zhan, Jeffrey Wang, et al.
👉https://t.co/tryf3SiNrw
📌#celastrol #fibroin #nanoparticles #pharmacokinetics
Celastrol shows potential anti-SARS-CoV-2 activity https://t.co/87j001XNzD @biorxivpreprint @usponline @usprp #AntiInflammatory #Coronavirus #Cytokine #DrugRepurposing #RNA #COVID #SARSCoV2 #Celastrol
Autophagy modulators from traditional Chinese medicine: Mechanisms and therapeutic potentials for cancer and neurod… https://t.co/YGBGTMlP1a
#INPST #NPMND #Autophagy #Baicalin #Berberine #Celastrol #Curcumin #Fucoidan #Matrine #Neurodegenerative #Piperine #Quercetin #TCM
Investigators demonstrated that #celastrol significantly dilated rat cerebral arteries both ex vivo and in vivo. | 🏫 Led by Dr. Alex Dopicoand colleagues at the University of Tennessee (@UTHSCResearch).
https://t.co/MTRwD7dHkW
#Celastrol, a bioactive compound derived from #plants, may protect against #angiotensin-induced #cardiac dysfunction. https://t.co/XPtzO4VImj
A nice collaborative work at @KU_PLEN to decipher biosynthetic steps in #celastrol biosynthesis. Check out our new publication here: https://t.co/QCNo3JmS5L
@Hemaisphere @nature @CellCellPress This is corporate warfare. Those ruffians at @nature are trying to capitalize on the time honoured @Cellcellpress brand. They can't reproduce our research, so they reproduce our name. #Celastrol is ours!
#mdpimolecules Optimization of Preparation and Preclinical Pharmacokinetics of Celastrol-Encapsulated Silk Fibroin Nanoparticles in the Rat https://t.co/TDvBP3p7O4 #silkfibroinnanoparticles #celastrol #optimizedformulation #bioanalysis #pharmacokinetics
Hoy hace cuatro años publicamos en @CellCellPress el descubrimiento de #celastrol, la droga anti #obesidad más potente en la literatura científica y que hoy se encuentra en estudios clínicos en humanos. @CienciaSumerce @clopezcorrea2 @CienciaCol
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