Top Tweets for #intrahost
Our study focused on #intrahost single nucleotide variants (#iSNVs, pronounced ‘eye-snivs’, e.g. C>T) of the cancer-causing human papillomavirus #HPV.
You can think of iSNVs as polymorphisms in the population of viruses infecting a single individual. 2/8

SARS-CoV-2 infection and persistence throughout the human body and brain
12/20/2021
#SARSCoV2_timeline #autopsy #SARSCoV2_pathology #viral_persistence #viral_evolution #intrahost #viral_diversity #mixed_infections
https://t.co/kPvJoGI9TU
"...the study points out the convergent #intrahost #evolution of specific #mutations in #SARSCoV2, as they emerged independently in previously described VOCs, VOIs and in the strain we studied."
Intra-host evolution of mutations + unmitigated transmission = unmitigated disaster
😱CONVERGENT WHAT NOW?!
"The high frequency of these non-synonymous mutations is consistent with multiple events of convergent evolution... specific mutations in the SARS-CoV-2 genome may represent positions with a fitness advantage."
https://t.co/AkimzK5fJl
Convincing evidence of within-host #intrahost recombination of #SARSCoV2 during an Alpha/Epsilon (~75%/25%) super-infection — two variants that are diverged enough to allow such detection. Evidence from deep sequencing, cloning, and contact tracing. No onward transmission.👇🏼
1/9 What happens during superinfection with different SARS-CoV-2 strains (hint: recombination)? A new preprint with @DarrenM98230782, Joel Wertheim, @nekrut and New York City (NYC) Department of Health and Mental Hygiene https://t.co/cVWyaHOA2e
#Intrahost genetic diversity is thought to facilitate #arbovirus adaptation to changing environments and hosts, and it might also be linked to viral #pathogenesis. Read more at https://t.co/KQo5c6QvNr

.@chasewnelson and his co-authors used dedupe in their study on the mechanisms of genetic diversity of West Nile Virus
https://t.co/gccFVK5Rpw
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