Top Tweets for #kcc2
Recent #Research by Jadwiga N. Bilchak (@mmscrc @PennMedicine) et al. finds that #KCC2 enhancers normalize reflex responses and improve #locomotor function after chronic spinal cord injury 🧠 ⚙️
📜 Read the study here: https://t.co/MVdrlfxZO7
Directly activating KCC2 could transform treatments for neuropsychiatric, neurodevelopmental and neurodegenerative diseases. Our President & COO, Meg Alexander, shares more below.
#KCC2 #Neuroscience
@HanganuOpatzLab @NatureComms @IPochinok @chini_mattia @tristanstoeber Congrats, very cool! As 'the ripples emerge in the mid of the second postnatal week', do we know if this also coincides with a shift in chloride gradient? #GABA #kcc2
The role of #KCC2 in recovery of consciousness from #anesthesia
https://t.co/LMXu5T2rEP #neuroscience
A Research Highlight about "Emergence of consciousness from anesthesia through ubiquitin degradation of KCC2 in the ventral posteromedial nucleus of the thalamus".
I heard…. It’s gonna be banging! Audition now! #KCC2
Our work “Restoring neuronal chloride extrusion reverses cognitive decline linked to Alzheimer’s disease mutations” has been accepted in @Brain1878 #Alzheimer #KCC2 1/4 🧵
https://t.co/2zSVoAPSJn
Therapeutic effects of #KCC2 chloride transporter activation on #detrusor overactivity in mice with #SpinalCordInjury
⌨Kyohei Watanabe, et al.
https://t.co/OqFS5L1Kbm
#AJPRenal #EfferentNerve
It was a pleasure to participate in the @Syngap1Fnd industry roundtable, and discuss the therapeutic promise of targeting #KCC2 in #neurological #disorders
2023 SYNGAP1 Industry Roundtable
Dr. Shane Hegarty, Chief Scientific Officer, Founder/Inventor at @Axonis_US Therapeutics #syngap1
https://t.co/o1zT9oOUA5
Look forward to @Syngap1Fnd 1st Industry Round Table on #drug development for #SYNGAP1 & related #neurological #disorders. Will discuss @Axonis_US first-in-class oral #KCC2 potentiator drugs for treating disorders of excitation/inhibition imbalance in CNS https://t.co/W7dX7pgjYZ
We are grateful to SynGAP Research Fund and @cureSYNGAP1 families for generously providing critical resources for a unique #research #collaboration between #academia and #biotech testing novel #KCC2-potentiator #therapies in #SynGAP1-related disorder #patient iPSC-derived neurons
SRF announces $130k collaborative grant to the Tang Lab @BostonChildrens & @Axonis_US to see if a #KCC2 enhancing drug will ameliorate #SYNGAP1.
Also quoted: @SVH_neuro, @KadamLab & @JMGraglia.
This is possible due to the generosity of our families.
https://t.co/CmdNY3gDsP
SRF announces $130k collaborative grant to the Tang Lab @BostonChildrens & @Axonis_US to see if a #KCC2 enhancing drug will ameliorate #SYNGAP1.
Also quoted: @SVH_neuro, @KadamLab & @JMGraglia.
This is possible due to the generosity of our families.
https://t.co/CmdNY3gDsP
Hiring @Axonis_US for in vivo #electrophysiologist & surgeon to join @KadamLab #epilepsy & #EEG group. Seek talented #neuroscientists join #team advancing first-in-class #KCC2 potentiator drugs for #neurological #disorders. Apply:
https://t.co/YO5tejf1NS
&
https://t.co/0jxdOjl1Zt
Kicchasudeep and puneeth rajkumaar rare video in KCC part || we miss you puneeth sir ❤❤
#kicchasudeep #puneethrajkumar
@KicchaSudeep @PuneethRajkumar
#Kiccha46 #KicchaBOSS𓃵 #kicchaforever #puneethsir
#rajkumar #kcc2
#Chloride transporters controlling neuronal excitability (@j_pressey, @miranda_dsr, @RaveendranVA, @Mawoodin @UofT) - new in @physiolrev
https://t.co/mBwvPK5aos
#neurophysiology #synaptictransmission #KCC2
Highlights from #KCC2
Absolutely incredible performance from "Billy 'The Kid' Adams" and the team at Trident Martial Arts Wirral.
30 seconds, first-round KO.
#staytuned for more information
-
#mma #ufc #boxing #bjj #muaythai #kickboxing #jiujitsu #fight #mmafighter
Imaging cortical #neurons in culture immunostained against the potassium-chloride co-transporter #KCC2 and I couldn’t resist from sharing this beauty ☺️ #ydklab #PCN_CERVO @CERVO_ULaval
Axonis is delighted to welcome Dr Shilpa Kadam to team. Expert in #epilepsy, #EEG & #neurodevelopmental disorders who will spearhead #translational #neuroscience, #drug development & #biomarker #research work in multiple indications to bring first-in-class #KCC2 drug into #clinic
CSO Shane Hegarty will present at #WorldOrphanUSA Congress on our #target #discovery and #drug #development strategy, & oral #KCC2-potentiating #therapy for #rare #neurological #disorders involving neuron circuit dysfunction
#RareDisease #patientengagement
https://t.co/WZ5w1OZNgp
Check Out this Speaker at World Orphan Drug Congress 2022!
Join Shane Hegarty as he discusses In Vivo Phenotypic Screens Identify Therapeutics for Common Pathologies in Rare Neurological Disorders.
You won’t want to miss out, so book your passes here: https://t.co/UNw1Wjpw4p
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