Top Tweets for #mutationalSignature
✨Just out. A super interesting study on mutagenesis in systemic sclerosis as a precancerous condition. Happy to have contributed by expertise in experimental #mutationalsignature analysis. Congrats @SainiNatalie & Sriram Vijayraghavan @serumraghav of @ResearchMUSC and coauthors!
Our new work highlights the importance of nucleotide excision repair for the removal of bulky endogenous DNA lesions in cells. With the new WGS data from unique rare cancers we confirm that Signature 8 is a marker of GG-NER deficiency. #MutationalSignature https://t.co/SczhisF3r9
✨NEW✨Hepatic angiosarcoma is a new tumor type linked to #aristolochic acid exposure and its #MutationalSignature. More here: https://t.co/Vnk9OXZMZW
Our 2022 @NatureRevCancer article https://t.co/SuV6xR61C3 lacked this important new information.
👇🏼👇🏼👇🏼
Our Oct issue, out NOW! With articles on aristolochic acid-associated cancers, NK cells in #immunotherapy, oncofetal reprogramming in #tumours. Plus a Viewpoint on #cancer nanomedicine & a #NRCToT on 3D imaging of human tumours!
💌 https://t.co/ZZ3dRK4N6i
@natrescancer
🧬🧫🔬 Our latest paper discussing the low mutagenic effect of ATR and CHK1 inhibitors in pseudo-haploid cells, HAP1, is out!
https://t.co/py8UszAiSh
#DNAdamage #MutationalSignature #DNArepair #ResearchPaper
Analysis of skin cancer genomes from xeroderma pigmentosum patients to study the role of defects in the components of NER and translesion synthesis on TMB, mutation profiles and genomic landscape of mutagenesis. #MutationalSignature #CancerResearch #DNA
https://t.co/GeofKu50yE
As an early Christmas treat, my first paper, about the novel mutational signature of Illudin S, is online in @repair_dna
Check it out!
https://t.co/22qsckXUvl
#Researchpaper #DNArepair
#MutationalSignature
Using novel #machinelearning tool, researchers contend they have for first time uncovered a pattern of #DNAmutations that links #bladdercancer to #tobacco #smoking. https://t.co/3C2JzpI15x #AI #cancer #DNA #carcinogens #CancerResearch #smokers #mutationalsignature #mutations
Using novel #machinelearning tool, researchers contend they have for first time uncovered a pattern of #DNAmutations that links #bladdercancer to #tobacco #smoking. https://t.co/TeVHHeSDv3 #AI #cancer #DNA #carcinogens #CancerResearch #smokers #mutationalsignature #mutations
The study builds on the team's 2020 @Nature paper (in collab with @HansClevers @JensPuschhof @Cayetanopm) which showed how pks+ E coli, a toxin-producing bacterium found in the gut, causes a #mutationalsignature linked to #colorectalcancer
https://t.co/YAHkHW0MhQ
2/n
We've added 21 copy number signatures to the COSMIC #mutationalsignature database following yesterday's @nature paper. Read our interview with Ludmil Alexandrov from @UCSanDiego to learn about the research, utility of the new data, & future hopes.
👇
https://t.co/kVyTMn4Ozm
Signposting BRCA1 BRCA2 SMARCA4 NTRK1 NTRK2 NTRK3 HRD #testing plus WGS with #mutationalsignature & TMB in the @NHSgms #test #directory for #ovariancancer on @OvarianCancerDY #WOCD2022 #CloseTheCareGap @HealthierLSC @LSC_CA_ALLIANCE
https://t.co/tZOqjOLJ9j
Exciting new paper from @SerenaNikZainal❗️
🧬#MutationalSignature analysis of WGS for 18,640 cancer samples
📊Previously unreported signatures identified. Common & rare signature concept established.
💻 Fit MultiStep (FitMS) algorithm developed
👇
https://t.co/3y5wxRwskl
Peter Campbell from @sangerinstitute presents a novel #mutationalsignature from studies in the liver, and questions why adjacent clonal populations in liver samples may have entirely different mutational profiles.
#mutationalsignatures21
#livertwitter #RacialDifference #mutationalSignature #hcc
A new article on "Racial difference of mutational signature in hepatocellular carcinoma" from Prof. Xin-Yuan Guan's team, The University of Hong Kong.
Reading for free!
https://t.co/szp6peWGfN
@ShimaghavimiMD @LouisHSLau
CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data. #TumorHeterogeneity #MutationalSignature #CancerGenomics
https://t.co/6c1S4nlHdR @NatureComms
My recent work has been published on #PLOSGenetics: Copy number signature analysis tool and its application in prostate cancer reveals distinct mu ... https://t.co/UPHPTC2beW #Bioinformatics #MutationalSignature #CNV
#MutationalSignature #sigminer v2.0 is out, some significant changes (including bugs and enhancement) have been done, please upgrade it!
The newest #Sigminer is out and it supports reading SV data and generating genome rearrangement signatures https://t.co/R3Sn34sZab #Bioinformatics #MutationalSignature
A new version of Sigminer has been pushed to CRAN, a quick start vignette is available now. Hope it helps :) #MutationalSignature https://t.co/ENb8CedwEo
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