Top Tweets for #pathology360
A ‘ S-M-A-R-T’ way to recall key 🔑 features of ✅PARKINSON DISEASE. Recall boosters series on Instagram: @pathology360. #MedStudent #MedEd #MedStudentTwitter #pathology360 #DrKishoreBanerjee
#ConceptThatMatters #ATaleOf02Cities : a #pathology360 Original : What’s the KEY DIFFERENCE between AML & CML? How to differentiate AML from CML on peripheral blood smear ?Let's make it very simple; I would give you an analogy: IMAGINE there are 02 neighbouring cities : 🔺City-AML & 🔺City-CML.
Now in both these cities ,suppose, delivery of newborns have increased:
So, in City-AML,newborns are taking birth very fast;but, these newborns are NOT able to mature into toddlers, young adults or adults : their development gets ARRESTED in newborn stage. So, we have too many newborns(Myeloblasts) in the City-AML😀.
On the contrary, in CML-city, there is increase in birth and these newborns are maturing normally..so,we have not only increase in newborns (Myeloblasts)but also increased number of toddlers(Myelocytes), pre-schoolers(Metamyelocytes), young adults(band forms) & adults (Mature neutrophils)in the CML-city .
1. If you have understood this analogy given by me well, it should not be difficult to differentiate AML from CML.
2. In AML, we see increased number of cancerous blasts. These blasts in AML divide uncontrollably.
But,these blasts CAN NOT differentiate into further mature cells. These precursor blast cells in AML have lost their ability to differentiate. These precursor blood-cells in AML are stuck in “ Blast stage “.
It results in progressive increase in blast cells in bone marrow which ultimately spills into peripheral blood.
The KEY problem here is that maturation of Myeloblasts mostly gets " ARRESTED " at immature myeloblast stage. These Myeloblasts can not become Myelocyte, Metamyelocytes and ultimately transform into the mature Neutrophils/granulocytes.
3. On the other hand, in CML, there is increased proliferation of Myeloblasts ;but, those Myeloblasts can mature and differentiate upto Mature Neutrophils(granulocytes))(🔺ADULT human being )
4. So, if you look at bone marrow or peripheral blood smear of AML , you mostly see predominance of blast (Newborn babies 👶 which can not mature).
5. But, in CML, you get mixed populations. Some are babies 👶 (Myeloblasts); but there is also increased number of toddlers(Myelocytes), pre-schoolers(Metamyelocytes), young adults(band forms) & adults (Mature neutrophils)
6. Tried to compare it with the given image; tried to assemble 04 different images together to give it a new meaning. #ConceptThatMatters #Medicine #Medico #MedStudent #MedStudentTwitter ; created & conceived by : Associate Professor Dr Kishore G Banerjee. #DrKishoreBanerjee #pathology360 ; Instagram:@pathology360
#NameTheDisorder : of the Day. Explanation is already provided in my short video explanation of the Day. #pathology360 #DrKishoreBanerjee. For #MedEd #MedStudentTwitter #medstudents #Medicine
Trachealization of Esophagus; What does the term mean ? Explained here. It’s typically described in Eosinophilic Esophagitis. #MedEd #medstudents #pathology360
#MedicinePearls : #Pellagra is caused by severe deficiency of Niacin ( also known as, Vitamin 📍B3). Pellagra is characterized by 📍3 "D's": diarrhea, dermatitis, and dementia. #MedEdu #MedTweet #pathology360
#CaseOfTheDay : for full case description, please follow the link : https://t.co/qyQiuskJmh #pathology360 #DrKishoreBanerjee #MedEdu
Stag= Male Deer 🦌; Horn = Horn 😃; ✅Staghorn Megakaryocytes or Megakaryocytes with staghorn-shaped nucleus are characteristic feature of : #QueryOfTheDay #Medicine #pathology360 #DrKishoreBanerjee
The concept of DIC _part 01 ( Disseminated Intravascular Coagulation) simplified : how I interpret it ? You can watch the full video here : https://t.co/NWdJ55qR9h #pathology360 #DrKishoreBanerjee
✅Bitot’s spots: grey patch on bulbar conjunctiva.Pathognomonic of ✅Vit-A deficiency.Caused by squamous cell metaplasia and keratinization of the conjunctiva. #education #medicine #Vitamin #vitaminA #usmle #KeyConcepts #mbbs #md #MBBS #neetpg2023 #NEETPG2022 #plab #pathology360
Nail-pitting and Onycholysis : characteristic of psoriasis. #pathology360
#strawberries🍓🍓🍓 and #pathology. Strawberry 🍓 is mentioned in many places in pathology literature. Many places, pathological findings are compared with strawberries. Here is a snapshot of the notable ones 😄👍. #pathology360:
QueryOfTheDay on #MENSyndrome : The lesion seen here is most likely to be seen in a patient of :
A. MEN 1 Syndrome
B. MEN 2A Syndrome
C. MEN 2B Syndrome
D. MEN 4 Syndrome. #ChooseTheMostAppropriateOption ; #pathology360 #pathology #medicine #education. Image courtesy: NEJM
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