Top Tweets for #protamine
Protamine administration led to a small increase in PAP after separation from CPB in patients undergoing pulmonary artery reconstruction or unifocalization surgeries. #protamine #PAP #congenitalcardiac
https://t.co/rbBnUfTZtO

Study from @icarindia #NBAGR show that genes associated with #protamine (PRM1 & TNP2) are highly conserved in Bubalus bubalis. Understanding these genetic underpinnings can have implications for
improving #buffalo bull fertility & semen quality.
@DrJitendraSingh @rajesh_gokhale

Protamine-Mediated Tangles Produce Extreme Deoxyribonucleic Acid Compaction | Journal of the American Chemical Society @UICscience @UICLAS #Protamine #Tangles #DNA #Compaction https://t.co/W0BLbPslnr
PROTAMINE in guidelines (image)
#PROTAMINE in our opinion (link)
https://t.co/XyfLFOBJMR
#eactaic2024

🔴Protamine and Heparin Interactions: A Narrative #2024Review
🔹#Protamine can not infact be defined as a procoagulant, as it is an antidote that might itself act as an anticoagulant
🔹https://t.co/MZpqc2occs
#CardioEd #CardioTwitter #cardiology #ECG #MedEd #cardiovascular

#Protamine was first isolated from salmon fish sperm but is now produced through recombinant biotechnology
#Protamine cannot in fact be defined as a procoagulant, as it is an antidote that might itself act as an anticoagulant
published today, free link https://t.co/aZb2p3tTx5
first author Martina Crivellari @crimar701

#Protamine cannot in fact be defined as a procoagulant, as it is an antidote that might itself act as an anticoagulant
published today, free link https://t.co/aZb2p3tTx5
first author Martina Crivellari @crimar701

Effects of DOACs on Tests of Hemostasis - @AaronGoodman33
#Cancer #Idacrucizumab #OncoDaily #Oncology #Protamine
https://t.co/JTbe5g5pf3
how to reduce #protamine after cardiac surgery (to 2/3 of total administered heparin)
@rmudanna #EACTAICannual @eactaic Budapest moderated by @MarcVives13

Excellent #heparin reversal / #protamine review @JerroldLevy .
I'm definitely cooking having salmon later today.
@JTHjournal

A study conducted by @KinanKneizeh et al with 897 patients undergoing #TAVR @UniklinikAachen confirms our findings that full heparin reversal with #protamine is superior to partial antagonization in preventing bleeding and vascular complications.
https://t.co/FL1letzhnB
Out latest research on the optimal protamine‐to‐heparin dosing ratio for the prevention of #bleedings in patients undergoing #TAVR has now been published. We found full heparin reversal to be superior to partial antagonization in preventing bleedings.
https://t.co/2AaKoSmOQ2

5/
Case report: hemorrhage in patient on #UFH
➡️ Use #Protamine sulfate
🚫 Not 1:100 with #heparin ➡️ elongation of clotting time
✅ But 2/3 of the dosage ➡️ full reversal without clotting issues (link)
➡️Protamine is useful also for #LMWH❗
https://t.co/C4go33uxS6
What an incredible experience at #EuroPCR! 🫀
Thrilled to have been part of this leading course with a record-breaking 11,500 participants. Grateful for the opportunity to present our results on using #protamine for bleeding prevention in #TAVR patients with recent #PCI.

Has everything been told about #protamine for the #prevention of bleeding events?
Not yet…what about patients with recent #PCI undergoing #TAVR?
We will present the results of our cooperation with @VTiyerili & @ProfHelgeMölmann today.
#DGKJahrestagung #DGK2023 @DGK_org

Protamine-mediated efficient transcellular and transmucosal delivery of proteins.
| Shyh-Dar Li @ubcpharmacy | @CC_CRS
[50 days' free access]
#protamine #proteindelivery #mucosal #cellpenetratingpeptide
https://t.co/AedFwZEOCW
Protamine-mediated efficient transcellular and transmucosal delivery of proteins.
| Shyh-Dar Li @ubcpharmacy | @CC_CRS
#protamine #proteindelivery #transmucosal
https://t.co/Uin6dD5CH3
The reversal of the anticoagulant and haemorrhagic potential of #LMWH with #protamine sulphate has been investigated in various studies
https://t.co/uqhLO4o3Ca
@crimar701
@LTHAnaesthesia
@RLH_TAG
@dundeegas
@ucianesthesia
@PeriopMedUCL
@OxfordNDA
@LondonAnaesth
@BRIanaesthesia
and here is a pilot study telling us that it would be reasonable to administer #protamine 0.8:1 (of the initial #heparine dose) when doing it blindly
https://t.co/thZFkC5UVh
@EchoSoliman
@Echotrainer
@pwierusz
@jiapenghuang
@JenelleBadulak
@SCVA1997
@PatrickFWouterS
@deramirezmd @JCVAonline @SCVA1997 @tahan_dr @md_monaco @fabiodoc64 @jiapenghuang @MarcVives13 @KhannaAshishCCM @docsanga yes!
also ‘standard’ #protamine (1:1) often induces coagulopathy
but nobody knows
and nobody cares
https://t.co/fmz1qhQDfV
it would be reasonable to administer protamine 0.8:1 (of the initial dose) when doing it blindly
even better to measure
@deramirezmd @JCVAonline @SCVA1997 @tahan_dr @md_monaco @fabiodoc64 @jiapenghuang @MarcVives13 @KhannaAshishCCM @docsanga yes!
also ‘standard’ #protamine (1:1) often induces coagulopathy
but nobody knows
and nobody cares
https://t.co/fmz1qhQDfV
it would be reasonable to administer protamine 0.8:1 (of the initial dose) when doing it blindly
even better to measure
More patients in the high dosing #PROTAMINE group received plasma (11 % vs 0 %; p=0.02) and platelet concentrate (21 % vs 6 %; p=0.04) compared to the low dosing #PROTAMINE group.
Abundant protamine dosing increased postoperative blood loss
https://t.co/EK8ixVbl2n

#Protamine is an antidote
protamine is not a pro-coagulant drug
protamine has anticoagulant properties
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