Top Tweets for #prothrombin
What Can Be Alternative to Warfarin - @flora_peyvandi
https://t.co/WmcNWX3KIL
#Hematology #Hemostasis #HemostasisNews #HemostasisToday #Medicine #Health #MedX #MedNews #MedEd #Prothrombin

#Warfarin may be more effective in high-thrombotic-risk conditions because it lowers #prothrombin levels, a clotting protein with a long half-life (60–72 hours).
This long half-life helps smooth out fluctuations in drug effect over time.
https://t.co/qccYK2M9PZ
“The Rise of “Tetra-Positivity”: #Patients positive for LAC, aCL, anti-β2GPI, and aPS/PT (anti-phosphatidylserine/#prothrombin) represent a distinct, high-risk phenotype with persistent #antibody profiles.”: https://t.co/NKkr9m7Czy from @hemostasistoday #AntiphospholipidSyndrome
First Case of the Rare Prothrombin Belgrade Variant in a Mexican-American Family with VTE
https://t.co/IihuvjxfPP
#Hematology #Hemostasis #HemostasisToday #Prothrombin #ProthrombinBelgradeVariant #Thrombosis #VTE #MedEd #MedX

📣 Is Heterozygous Prothrombin Mutation associated with Venous Thromboembolism?
📖 Wu et al. identified novel #prothrombin mutations among 347 patients w/ unprovoked #VTE or family history of #thrombosis ⤵️
🚨 Read in TH 👉 https://t.co/lQdOzWmZVV
#Hemostasis #Thrombophilia

It was a very useful and informative session given by @LabPozzi at #ISTH2024 about the smFRET method to investigate the protein dynamics and conformational roles of #prothrombin and #B2GPI in #APS.

#Zinc #supplement (#polaprezinc) improves #albumin, #prothrombin time activity & #hemoglobin in chronic #liver disease
���@_atanas_ @_INPST @ScienceCommuni2 @DHPSP @HeidiHmoretti @AskDrShashank @heniek_htw https://t.co/mbr42ts1HH
The #letter “Pediatric #hemophilia patient: Successful #desensitization for drug-induced fixed #urticaria with #prothrombin complex concentrate” published in the #pai_Journal is available here 🔗 https://t.co/6Nyml23eZh
#Pediatrichemophilia #prothrombincomplexconcentrate

9c) #Prothrombin complex concentrates #4F_PCCs contain variable amounts of factors II, VII, IX, X; proteins C & S, ATIII & heparin.
- Dosed based on FIX component
- Differ from 3F-PCC because they contain FVII
#PCC replaces factors & MUST be given w/ Vit K to synthesize new ones

For patients at risk for #massivetransfusion due to #trauma, does #prothrombin complex concentrate result in better clinical outcomes? The result might surprise you!
#PCC #hemorrhage #stopthebleed #transfusion #blood #anesthesia #traumasurgery #ER
https://t.co/yHe1goO5rV
#vitamink
essential for;
√ blood clotting
√ Aid wound heal
√ Health bone
√ #prothrombin is a vitamin k- dependent protein directly involved with blood clotting.
√ #osteocalcin is a protein that requires vitamin k to produce health bone tissue @foodcoopkenya

3/
What if it's not an elective patient??
Use #reversal agents when needed❗
🔹#Idarucizumab for #dabigatran
🔹#Andexanet for #apixaban and #rivaroxaban
💡#Prothrombin complex concentrates in addiction
https://t.co/M8JVKDYDnE

Do #FactorVLeiden or #prothrombin gene mutations increase risk of #coronaryarterydisease? In this study, Agosti et al found that #FVL mutations were associated with an increased risk of premature CAD in young Iranians.
#cardiotwitter
@flora_peyvandi
https://t.co/tyhwgCNRwD

Check out Coag-Sense #Prothrombin Time PT/INR Self Test Meter Monitor & AC Adapter & Case #BuyIt #ebay #ProthrombinTime #ptinr #forsale #healthcare #nursing https://t.co/nyvNvnC8Ts #eBay via @eBay
Compared with standard care (fresh frozen #plasma), #prothrombin complex concentrates reduce #RBC transfusion rates in patients who experience #bleeding issues after #heart surgery. Check out the evidence from @CochraneLibrary 👉https://t.co/VW575p3l8e @CochraneNursing

It wasn’t until after Julie gave birth at her #postpartum follow-up appointments that she discovered she has #factorVLeiden & #Prothrombin (factor II) genetic clotting disorders. She was convinced by two doctors that she was just experiencing #sciaticpain or a “pregnancy injury."

Did you konw? 'Prothrombin Time' (PT) discovered by Armand Quick in 1932 is also sometimes called the 'Quick Time' (QT).
To know more about History of #Coagulation 👉 https://t.co/QNP74fyf4p
#HistoryOf #Coag #ProthrombinTime #Prothrombin
23) Remember B (bleeding) back in our ABCD priorities for this pt? We must move on to #anticoagulation reversal. He takes apixaban! Remember Factor Xa Inhibitors (FXa 🛑) act by binding to the active site of FXa, thus preventing the conversion of #prothrombin to #thrombin:

35) Unlike Russell viper venom in the DRVVT (which activates Factor X and is affected by VKAs & DOACs), Taipan snake venom directly activates #prothrombin and can be used for LAC testing on warfarin (and even on Xa-inhibitors when at trough levels)

Some of my PhD work is available on a preprint. It’s an innovative mouse model to study prothrombin in a very elegant way. Please have a read and share. Thanks! #preprint #prothrombin #phdlife https://t.co/9X3mWkLN4y
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