Håvard T. Lindholm

Bioinformatics, epigenetics, immunology and more! @havardtl.bsky.social

[Håvard T. Lindholm @havardtl]

Excited to share our most recent work! Thanks to @Amir_Hosseini85, @rmzchen, @decarvalho_lab and the other co-authors for the great collaboration.

[Cell Reports @CellReports]

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer https://t.co/lDQdTHD6Q9

[Daniel De Carvalho @decarvalho_lab]

Our latest manuscript of our viral mimicry work is out: ‘Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer’ https://t.co/RfuzwjwyQj

[Håvard T. Lindholm @havardtl]

@Amir_Hosseini85 @rmzchen @decarvalho_lab And don't miss the co-publication: https://t.co/D8bJVjI4aK

Excellent work which allows you to delve even deeper into the world of XRN1 and IFN

[Håvard T. Lindholm @havardtl]

Excited to share our most recent work! Thanks to @Amir_Hosseini85, @rmzchen, @decarvalho_lab and the other co-authors for the great collaboration.

[Cell Reports @CellReports]

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer https://t.co/lDQdTHD6Q9

[Håvard T. Lindholm @havardtl]

@MennoOudhoff @rmzchen @decarvalho_lab @CharlesIshak Thanks :)!

[Håvard T. Lindholm @havardtl]

Proud to present our recent review where we discuss mechanisms where endogenous retroelements act as alarms for disruptions to cellular homeostasis. Now out in @trendscancer!
https://t.co/vSPmUpssRG

[Daniel De Carvalho @decarvalho_lab]

Happy to publish this opinion/review where we argue that endogenous retroelements act as a 'fire alarm' for disruptions to several cellular processes such as heterochromatin, splicing, RNA editing, among others. great work by @havardtl and @rmzchen https://t.co/FYx3euY1PT

[Science Immunology @SciImmunology]

A new study in #organoids and mice identifies the proteins regulating a positive feedback pathway between #TuftCell and #ILC2s that can lead to excess inflammation if unchecked.
@NTNU @WCIPGLASGOW
https://t.co/wMJrPEttdc

[Håvard T. Lindholm @havardtl]

@HausmannAnnika Thanks! Hope you find it interesting :)

[Håvard T. Lindholm @havardtl]

Our paper is out! Thank you to all collaborators for fantastic help putting this story together!

[Ifor Williams @IforRWilliams]

BMP signaling taps the brakes on runaway tuft cell hyperplasia during type 2 intestinal immunity. Stellar images of #organoids are among the highlights of a new @SciImmunology paper from @MennoOudhoff #CEMIR @NTNUnorway @WCIPGlasgow
Read it here ➡️ https://t.co/3Zfjjh9dcp

[Håvard T. Lindholm @havardtl]

@SajidMarhon Thanks!

[Ifor Williams @IforRWilliams]

BMP signaling taps the brakes on runaway tuft cell hyperplasia during type 2 intestinal immunity. Stellar images of #organoids are among the highlights of a new @SciImmunology paper from @MennoOudhoff #CEMIR @NTNUnorway @WCIPGlasgow
Read it here ➡️ https://t.co/3Zfjjh9dcp

[Håvard T. Lindholm @havardtl]

@ClaireDrurey @MennoOudhoff @Nicola_L_Harris @MartaCampillo_ Congratulations ! And thank you for the collaboration, it was a pleasure :)

[Rafael Irizarry @rafalab]

For those that don't quite understand why I include "Do not use Excel" as a recommendations for how to monitor #COVID19 with data, here is one example (the main reason is reproducibility):

https://t.co/nLIZCvAUGu

[Håvard T. Lindholm @havardtl]

Proud to be part of this work! Thanks to everyone involved.

[Michael Hoffman @michaelhoffman.bsky.social @michaelhoffman]

1/Now on @arxiv: our letter about the recent @GoogleHealth cancer screening paper. "The importance of transparency and reproducibility in artificial intelligence research" by @bhaibeka @robtibshirani @HastieTrevor @johnquackenbush @hugo_aerts and others. https://t.co/GbGzE5tfqX

[Håvard T. Lindholm @havardtl]

Denne fredagen skal jeg holde fredagsforlesning på St. Olavs! Her skal jeg prate om tarmcellene i dette bildet. Kom til KA12 kl 8:00 hvis du vil høre mer om dem :).

Mouse intestine, DNA stained with DAPI in blue,… https://t.co/hXzCYLo1CB

[Håvard T. Lindholm @havardtl]

@HausmannAnnika @MennoOudhoff Thanks! Really enjoyed your talk as well. Epithelial cells should definitely not be underestimated in infections in the gut!

[Håvard T. Lindholm @havardtl]

@Ridjobrki haha, yeah it's something to remember for sure!