Ghmkin Hassan

[dana_peer @dana_peer]

I am very pleased with our latest paper, spearheaded by 3 incredibly talented first authors @chris_cowley14,@LFSoto12 and @SairajSajjath with @ElaineFuchsLab. Here we show that cells can remember past injury for a long time! https://t.co/lL0VYIyNan

[Daniel J Drucker @DanielJDrucker]

Under severe inflammatory conditions such as LPS administration, pancreatic production of GLP-1 functions in an immunological rather than a metabolic role to directly regulate local macrophage accumulation https://t.co/yJlwfgmE7I

[Cell Metabolism @Cell_Metabolism]

Neutrophil-mediated anti-tumoral effects of caloric restriction https://t.co/rFSlAZsuZX

[Nature Metabolism @NatMetabolism]

Lipid-dependent accrual of a subset of monocyte-derived macrophages is essential for tissue regeneration https://t.co/u2bFPc2lxf

[Anirban Maitra @Aiims1742]

Obesity and Cancer: A Translational Science Review
https://t.co/NLBfN3mp3h
"Overweight and obesity account for approximately 10% of new cancer diagnoses annually in the US and up to 50% of certain cancers such as endometrial and hepatobiliary cancer"
@Neil_Iyengar

[Arndt Vogel @ArndtVogel]

Emerging landscape of KRAS inhibitors in cancer treatment
@Cancer_Cell
https://t.co/sc6Jbr36hh
👏great review
👉Tsunami of new drugs and oppertunities
@myESMO @ASCO

[Prof. Kevin J. Tracey, MD @KevinJTraceyMD]

Why do GLP-1 drugs fail to cause fat loss in some? A mitochondrial switch ("SLC25A45") controls whether mitochondria burn fat or carbohydrate, and removing it (in mice) makes GLP-1 drugs stop working for fat loss entirely.

"Mitochondrial control of fuel switching via carnitine biosynthesis," Science, Vol 391, Issue 6786, (10.1126/science.ady5532)

[Nature Metabolism @NatMetabolism]

Early-activated extracellular matrix proteins shape the metabolic and spatial dynamics of the kidney fibrotic microenvironment https://t.co/fslhIxnBuR

[Patrick Hsu @pdhsu]

we have long known that people who live at altitude die less from cancer. @arcinstitute investigators developed an "altitude-in-a-pill" drug that tunes how your red blood cells bind to oxygen

today, they demonstrated this enables potent anti-tumor activity in cancer models 🫢

[Jan Broder Engler @JanBroderEngler]

You can save #tidyplots in multiple formats by piping through multiple rounds of `save_plot()` 🤩

#rstats #dataviz #phd

[Nature Rev Immunol @NatRevImmunol]

Biochemical signals from the extracellular matrix in inflammation and tumour immunology https://t.co/QViFIhK3TX

[Waggoner Lab @LabWaggoner]

Macrophages can engulf targets whole (phagocytosis) or nibble them in small fragments (trogocytosis), a decision controlled by cortical tension in the targets (high tension favors former, low latter)
https://t.co/bWqUvSxpRs
https://t.co/eBZHkmmHb6
@NatureCellBio @UCBerkeley

[Waggoner Lab @LabWaggoner]

Architecture of the neutrophil compartment @Nature
https://t.co/8UNowJOWAd @ivanbamartin @AndrsHidalgo16 @lai9uan @danielacerezo @Yale 🇨🇳🇪🇸🇺🇸

[Anirban Maitra @Aiims1742]

New @trendscancer commentary:
Tumor-intrinsic dichotomy shapes cellular heterogeneity in #PancreaticCancer
https://t.co/cdZzPTzgcZ
Original paper:
SPP1 is required for maintaining mesenchymal cell fate in pancreatic cancer
https://t.co/zpwlhNvIV6

[FlorianLab_StemCellAging @Florian_SCaging]

Finally the official published version👉🏽 https://t.co/DCI2sn9NVT!!! It is about #mechanobiology, #epigenetics, computational image analysis, regenerative capacity and #hematopoietic #stemcellaging and #rejuvenation💥💥💥
@idibell_cat @icreacommunity

[Anirban Maitra @Aiims1742]

Exercise as anti-cancer medicine
(“Exercizumab”)
@Cancer_Cell
https://t.co/51bb4qGQfY
@JCO_ASCO
https://t.co/tBcD44WuML

[Dr. Jean Fan @JEFworks]

What an amazing resource! I made a quick screen recording of me using the apps to look at marker genes associated with cell-type annotations and explore cell-type-specific gene expression changes with different cytokine perturbations to demo. Looking forward to using this more!

[Christoph Bock Lab @ CeMM & MedUni Vienna @BockLab]

🗨️ Just published in @NatureBiotech: Our CellWhisperer AI enables chat-based analysis of single-cell sequencing data. You can talk to your cells & figure out the biology without writing any computer code. Paper link and annotated walkthrough in the thread below (1/11)

[Myriam Chalabi @MyriamChalabi]

Very proud and happy to share that our work on neoadjuvant IO in pMMR colon cancers has been published online in @Nature after presentation @myESMO #ESMO25. Preview: https://t.co/KR6mBytwV3 Read on how genomic instability, P53mt and proliferation may aid in predicting responses.

[Martin Picard @MitoPsychoBio]

When we look at life up close, like chromosome separation, it's always so jiggly! 😯

This is the stuff our energy flows through.

No wonder that human lives and experiences also are jiggly, unstable, and beautifully unpredictable.