Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19 https://t.co/UetaTLlO3L
1/ We're seeking enthusiastic students & post-docs to join @ShenYingZhang1's team in https://t.co/Pir8ly9814 to explore the human genetic and immunological basis of viral encephalitis, in a global cohort of patients with encephalitis due to herpesviruses, arboviruses and others.
I am very excited to share the final story of my PhD, online now as a pre-print in @biorxivpreprint, where we dissect the opposing effects of antibody-feedback and memory T cell help on recall germinal centers (GCs). 1/n
https://t.co/sKiEUOYiiT
Excited to share our group's first manuscript describing new anatomical connections that allow the eyes to act as an "immunological window to the brain" 👁️🧠 (1/)
https://t.co/mpIEqvZSE5
Stanford researchers and their colleagues have identified more than 1,000 genes linked to the development of severe COVID-19 cases that required breathing support or were fatal. https://t.co/Vfv0EJcMWc
#COVID19#Genetics
Vaccines that reduce infection & disease are needed to combat the pandemic. Here, @tianyangmao@BenIsraelow et al. describe our new mucosal booster strategy, Prime and Spike, to induce such immunity via nasal delivery of unadjuvanted spike vaccine 🧵 (1/)
https://t.co/J4NuUgiI7e
Incredible that Omicron appears to have evolved towards "a more compact
architecture"!
Our predictions in https://t.co/jaYSq2uxsA on spike opening being a trade off between immune evasion and receptor binding seem to be panning out!
How do the Omicron mutations affect its binding to ACE receptor & result in loss of activity of most monoclonal antibodies?
Elegant cryo-EM work by @veeslerlab and colleagues
Remodeled N-terminal domain and impact outside RBD, NTD defined
https://t.co/4cv0N1Dw9L
@ScienceMagazine