Every week, the average person ingests up to the equivalent of a 5-gram credit card in plastic.
Microplastics are now thought to accumulate in the brain at 10 to 20 times the rate as other organs and, worse still, are 10-times higher in the brains of people who died from dementia.
Most major organ systems are impacted.
While the consequences of the pervasive presence of microplastics are still being understood, the microplastics themselves are carriers of harmful chemicals like BPA, phthalates, and PFAS.
These harms are less ambiguous.
Acting as a xenoestrogen, BPA, for example, has strong evidence that it affects multiple dimensions of child development ranging from the neurological to sexual and behavioral.
Pregnant women with high BPA levels are six times more likely to have a child diagnosed with autism by age 11 compared to those with lower levels.
Multiple lines of converging evidence demonstrate both reproducibility and even mechanism: BPA suppresses the aromatase enzyme, leading to anatomical, neurological, and behavioral changes in male mice that mirror aspects of autism spectrum disorder.
In a study of 40 healthy young men, all were found to have microplastics present to some degree in their semen. Men with elevated BPA levels have lower sperm quality, reduced testosterone, and abnormal sperm morphology.
The cardiovascular system is not spared.
Microplastics have been found embedded in arterial plaques, and their presence correlates with a 4.5-fold increase in the risk of heart attacks and strokes.
Cancer risk is another alarming aspect.
Childhood exposure to phthalates is associated with a 20% increase in overall cancer risk and nearly a threefold increase in specific cancers like osteosarcoma and lymphoma. BPA's estrogen-mimicking properties have been linked to breast cancer development, promoting the growth of estrogen-sensitive cells and disrupting normal hormonal regulation.
My latest episode will no doubt stir some anxieties, but were not powerless. Also discussed are actionable ways to minimize exposure by avoiding the worst offenders.
Episode 95 is available on X, YouTube, Spotify, and everywhere else. Links in comment.
Timestamps:
0:00 - The extent of the problem
2:12 - Top sources of exposure
4:01 - Contamination of our water
5:03 - BPA, phthalates, & PFAS (forever chemicals)
7:05 - How heating plastic affects BPA exposure
9:20 - Our unfortunate habit of eating credit cards
11:32 - Microplastics in major organs
14:04 - Crossing the blood-brain barrier
15:00 - How microplastics affect a developing fetus
15:54 - The bloodstream is a highway for microplastics
18:11 - Endocrine and hormonal effects
18:34 - Mimicking of estrogen
23:08 - Consequences in pregnant women
25:34 - How phthalates affect reproductive health
26:35 - Involvement in autism
29:57 - Side effects of prenatal BPA exposure
32:17 - The brain may be a super-accumulator of plastic
34:50 - Human brain microplastic levels are rising
36:06 - Lost fertility in women
38:07 - Changes in sperm quality
39:23 - Microplastics in sperm
40:59 - Why the heart suffers
42:51 - Microplastics in arterial plaque
43:56 - How BPA affects blood pressure
45:58 - Risk of cancer
50:31 - Forever chemicals in sparkling water
53:02 - Reverse osmosis filtration
54:56 - Food-based strategies for limiting microplastics
56:30 - The "myth" of BPA-free plastics
58:14 - Is salt a source of microplastics?
59:18 - HEPA filters
1:00:52 - Choose your clothing wisely
1:01:47 - How to prevent release of microplastics (from laundry)
1:02:32 - Receipts and thermal paper
1:04:17 - Excretion and breakdown
1:06:28 - Sulforaphane for detoxifying
1:08:38 - Can dietary fiber increase microplastic excretion?
1:10:15 - Are plastic chemicals excreted through sweat?
1:11:22 - Do excretion strategies work for "forever chemicals"?
I found a guy who goes around the US asking 70 to 100-year-olds their:
• Biggest Regrets
• Biggest Lessons
• Advice to their younger self
Oddly enough, most of their answers are the same…
Here are my top 8:
This is Elon Musk.
He runs 5 billion-dollar companies, has 11 kids, and still has time to sh*tpost on Twitter.
I had to know how he manages his time.
Here’s what I found:
I’m only 45 minutes in, but this conversation between @JamesClear and @tferriss is already the best podcast I’ve listened to this year.
Will unpack more of what I’ve learned in a future newsletter, but if you do nothing else today, listen to this!
https://t.co/j4BMRCRI4q
Subjects that should be mandatory in schools:
- Taxes
- Coding
- Cooking
- Insurance
- Weightlifting
- Self-defense
- Survival skills
- Social etiquette
- Public speaking
- Personal finance
- Car maintenance
- Basic home repair
- Stress management
What would you add?
The #Telcoin App now offers $TEL #Staking! #TELtheWorld about this exciting new feature and get rewarded for bringing new users to the Telcoin ecosystem! #DeFi#SelfCustody#UserOwnership
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There is a HUGE demand for video editors who understand how to edit for YouTube and social media.
99% of video editors don't know how to do that.
If you can learn this skill, you're basically guaranteed clients who will pay tons of $$$.
Some tips:
Volume Thread
Someone DM’d me to ask why I keep saying we need increased volume to get through a resistance level I thought I’d try and explain using $tel
(1 of 5)
1/ I sold half my #bitcoin at $30, lost more in MtGox, btce, cryptsy & cryptopia as well as had a partner in a mining business disappear, losing all of my miners.
Survival advice for those in crypto who had big losses from Celsius, Luna, FTX & DeFi rug pull #ponzigeddon 2022:
99% of the programmers only know the basic git commands (push, pull and commit)
These 10 git commands will save you hours of research time when you're stuck:
This is the resume I used to get my job at Microsoft in 2019.
While it's certainly not perfect, there are a few things that helped me in the process and I'll show them to you, using colors 👇
A 🧵 with 7 tips to improve your resume and stand out