Computational chemist and team leader @ICSN_lab @INC_CNRS @CNRS. Drug design, antibiotic resistance, docking, MD, QM. Views are mine. RT is not endorsement.
Very happy to announce that our review on class C beta-lactamases is now published in @ASMicrobiology's #ClinMicroRev: https://t.co/5lnFf04tDv. Great collaboration with Alain Philippon, Guillaume Arlet and Roger Labia.
Very proud be invited by @IorgaBI@ICSN_lab to talk about work performed @NantesUniv. Happy to present the research, and to have fruitful discussions with many colleagues.
Le Prix en Sciences biomédicales fondamentales (Prix scientifique Joseph Maisin) est attribué à Jean-François Collet, Professeur à @UCLouvain_be et co-Directeur @deDuveInstitute, qui a mis au jour de nouveaux mécanismes cellulaires fondamentaux.
Work from the @JFClab finds that about half of lipoproteins destined to the E. coli outer membrane display disordered peptides at their N-termini, which are required for optimal trafficking. Free to read: https://t.co/sA5DjoEaEr https://t.co/dTn2fKvsx9
Happy to announce our last paper: how disorder controls lipoprotein targeting. Congrats @JessicaelRayes1 queen of the ultracentrifuge :) beautiful work, journey with @MichaelDeghelt@IorgaBI@bluegreen812@NaemiC thanks @Welbio_asbl @UCLouvain_be @frsFNRS https://t.co/Pa5iTlcmpj
In October 1960, Institut de Chimie des Substances Naturelles (ICSN) started activity in its brand new building in Gif-sur-Yvette. Today we turned 60 #ICSN60@ICSN_lab @INC_CNRS @CNRSIdFSud@UnivParisSaclay
You know OmpA, right? Did you know that it plays a role in stress sensing? check our new article on OmpA and sensor RcsF. Congrats to @KDekoninck@IorgaBI and co-authors at @deDuveInstitute @UCLouvain_be @IBS_Grenoble Merci @Welbio_asbl @frsFNRS
https://t.co/OKUOYRtiaX @eLife
👏 ‼️ Félicitations à Jean-François COLLET @JFClab, Professeur à l’@UCLouvain et co-Directeur du @deDuveInstitute, lauréat du Prix Quinquennal #FNRS 2020 en Sciences biomédicales fondamentales (Prix scientifique Joseph Maisin).
Happy to share with all of you, our recent work on "Defining the function of OmpA in the Rcs stress response" !
with @IorgaBI@JFClab@deDuveInstitute @UCLouvain_be @Welbio_asbl
Did you know that OmpA helps E. coli to deal with stress?
Check our new preprint on the relationship between OmpA and the stress sensor RcsF ! Molecular dissection from @KDekoninck@IorgaBI and other lab @Welbio_asbl @deDuveInstitute members !
https://t.co/LkcDDMwpan
Découverte majeure de @JFClab & coll. dans la lutte contre les infections bactériennes : observer BamA en pleine action.
Des recherches @Welbio_asbl @Train2Target publiées
dans la prestigieuse revue @nchembio
https://t.co/veQC3na2nQ
A new paper from @JFClab @RaquelRguezAl @RemautHan@RadfordLab & colleagues show that β-barrel assembly machinery component BamA traps substrate inside the barrel lumen, supporting push-pull substrate export. Readable link at https://t.co/cQlayQH7En.
https://t.co/4tmU2Dlndv