Isaac Bean

Technology to reduce suffering and create joy. Design/build molecules and machines.

[Nate Bennett @naterbennett0]

1/7 Improving de novo Protein Binder Design with Deep Learning (https://t.co/M3JITN1nOZ) We show that AF2 is an effective predictor of whether a de novo designed miniprotein will bind to the intended target or not.

[Michael Mina @michaelmina_lab]

1/

Successful Public health Programs rely on Engineering principles as much as medical ones

It’s rare that public health is discussed with Engineering

But it should be.

Public Health Engineering Depts. should exist!

A wonderful article by @paimadhu
https://t.co/gXTsnQPsmj

[Isaac Bean @isaacbeing]

So proud to have met @jensstoltenberg at the South Pole Station.

Thank you for leading the fight for light during these dark times.

[David Juncker @DavidJuncker]

Delighted to announce the publication of our work on *Microfluidic Chain Reaction* (MCR) in @Nature.

MCR help realize a true lab-on-a-chip and could perform medical tests. You may download, modify, and 3D print your own MCR chip 😎

https://t.co/pXamlKhJAV
1/n

[Josh Lawrence @JMLawrence_]

Ever wanted to turn on a gene with electricity? Our work on #synbio and #electrochemistry tools for electronic control of gene expression is out now in @ScienceAdvances! ⚡🦠 Here's a summary of our findings 🧵 https://t.co/E2bX4E1k28 1/11

[Isaac Bean @isaacbeing]

1700 ELO. Think I’ll go eat some blitznses.

[Jack O'Meara @Jack_O_Meara]

Feels like style and design has traditionally been an afterthought in biotech (understandable given we’re making drugs prescribed by doctors), but perhaps that changes in an era of talent wars and new technologies.

Art, science, and entrepreneurship are each rooted in creation.

[cas @cas_smith]

designing with biology is going to be so beautiful

if we do it right

🤞

[ClyffordStillMuseum @Still_Museum]

Start your new year at the Clyfford Still Museum! Explore the exhibition, A Decade of Discovery: Clyfford Still in Denver, and make discoveries!

[Olivier Borkowski @O_Borkowski]

E. coli consortium for biodegradation:

Artificial Consortium of Three E. coli BL21 Strains with Synergistic Functional Modules for Complete Phenanthrene Degradation
https://t.co/43cZlLjJ8Q

[JM Rothberg @JMRothberg]

So live a life you will remember

Launched https://t.co/GcYl4GCglW

Discovered #Omicron on @iontorrent

When thunder clouds start pouring down

WildFire, SBS, Zemax, hack like Woz or Python Pi

These are the nights that never die

email [email protected]

[JM Rothberg @JMRothberg]

If you can build & use equipment like @Craggs_Lab please come join us.

We are looking for single molecule talent. Molecular biologists, biophysicists, coders. Tenacious, Joyful, entrepreneurial.

[email protected]
Send TWO references to
[email protected]

Redo time:

[JM Rothberg @JMRothberg]

Intern with me. Land & Sea. Winter, spring, summer & fall.

Want first crack at starting the next @4Catalyzer company?

Do molecular biology & coding projects in one-third the time most competent people think possible?

Email CV & have references sent to [email protected]

[JM Rothberg @JMRothberg]

FDA approved @DetectTest.

You you can order a PCR-quality test for home use THIS MORNING!!!

https://t.co/5KJ9B7Xr6z

[Christina Agapakis @thisischristina]

“But biological design will not be limited to steel tanks forever. What do we want to do after fermentation?”

[Ginkgo Bioworks @Ginkgo]

"Around the world, scientist and entrepreneurs are integrating abundant renewable energy, more powerful batteries, breakthroughs in fields like synthetic biology, to invent a better future that is healthier and more affordable." - @BarackObama

https://t.co/NKLPPbpytV

[Twist Bioscience @TwistBioscience]

A look at #syntheticbiology’s embodiment and advancement of equity, humility, sustainability and solidarity over time. #synbio @wef

Revisiting and Realizing the Promises of Synthetic Biology | World Economic Forum https://t.co/pSLCiBmW09

[Angel J. Ruiz-Moreno 🇲🇽 @ruiz_moreno_aj]

My first release of #Jupyter_Dock: Molecular Docking integrated in Jupyter Notebooks (Git repo: https://t.co/cJJe2TcRA9)

Notebooks for:

- Molecular Docking
- Virtual Screening
- Blind Docking
- Reverse Docking
- Docking Analysis

Example:
https://t.co/o0dz7VlH06

#compchem

[Elliot Hershberg @ElliotHershberg]

We are living through a renaissance in the field of computational protein science. This has enormous implications for biotechnology at large. Check out my COB highlight of the amazing recent work from @UWproteindesign on protein binders:
https://t.co/uUXRqGyL8P

[Jonathan Pritchard @jkpritch]

Today marks the 25th anniversary of Neil Risch and Kathleen Merikangas' classic 2-page paper that articulated GWAS as the future of human genetics. A short thread.
https://t.co/f5Eb9lcpd2