Jackson Thorp

NHMRC Emerging Leadership Fellow | Postdoctoral Research Officer | Translational Neurogenomics Lab @QIMRBerghofer | Psychiatric Genetics

[IBG @IBG_CUBoulder]

You've heard of DNA, but what about GNA? New preprint from @jacksonthorp and IBG member Andrew Grotzinger that introduces Genomic Network Analysis (GNA), an open-source multivariate tool for performing network analysis using GWAS summary statistics https://t.co/Cqrk02CFYY

[Jackson Thorp @jacksonthorp]

Our review of the genetics of substance use disorders is out now in @molpsychiatry
@zac_gerring, @DerksEske, Jorien Treur, Karin Verweij

https://t.co/x6b15UionS

[Jackson Thorp @jacksonthorp]

We are hiring postdocs! Join the @DerksEske lab in warm and sunny Brisbane! Get in touch if you are interested in 1) multivariate genetic modelling of psychiatric/related traits; and/or 2) functional interpretation of GWAS loci/drug repurposing. More info https://t.co/Y1kCNDMGbo

[Eske Derks @DerksEske]

An exciting study by Burstein et al. investigated the genetics of binge eating disorder. We discuss the main findings of their work
https://t.co/qyWUf6TbDz
@zac_gerring @jacksonthorp @QIMRBerghofer @NatureGenet

[Jackson Thorp @jacksonthorp]

Our new paper identifying drug repurposing candidates for anxiety is out now! https://t.co/ppC3STd18B

Big congrats to @DWoodward92 for his first publication. Many more great papers to come.

[Damian Woodward @DWoodward92]

My first publication is now out in Psychiatry Research! Investigating drug repurposing candidates for treatment in anxiety. Huge thanks to co-authors @zac_gerring @DerksEske @jacksonthorp @AkosileWole @egamazon & Jue-Sheng Ong @QIMRBerghofer
https://t.co/dMuVQYhvHQ

[Miri Forbes @MiriForbes]

Ever wondered how many symptoms make up all of adult psychopathology described in the DSM-5? It’s 628!

How many do you think repeat across multiple diagnoses? If you answered 231 symptoms repeating a total of 1022 times (median 3 times per symptom, range 2-22), good job!

🧵

[Jackson Thorp @jacksonthorp]

The last of my PhD papers is now published!

We looked at the association between depression PRS, trauma exposure, their interaction, and individual depression symptoms @PsychiatryResJ
Big thanks to @DerksEske @zac_gerring and all co-authors

https://t.co/HGZ1zK81Fw

[Adrian Campos @AdrianGenepi]

Today, our paper on attrition and selection using data from the Australian Genetics of Depression study was published. (1/8) https://t.co/I3Z3W9ieej

[Jackson Thorp @jacksonthorp]

Our article summarising some of the key challenges for the field of psychiatric genetics is out now in @NatureGenet. As always, an absolute pleasure to write this with @DerksEske and @zac_gerring
@QIMRBerghofer

https://t.co/58ariZHYqF

[Brittany Mitchell @Britt_Mitchell1]

In a slight shift in focus, our most recent study, published today in @NatureComms, was a large GWAS meta-analysis of acne. Using data from 9 research centers around the globe we were able to identify 46 variants associated with acne risk (29 novel).

[Adrian C. @AdrianCamposG]

Very proud of this piece of work where we look at the aetiology of antidepressant side effects in a large sample:
https://t.co/siSAXVVuwZ

[Adrian Campos @AdrianGenepi]

Our preprint exploring sociodemographic and genetic factors linked to optional prescription record linkage in the AGDS is out! Thanks to everyone involved in this important study!

[Dr William Reay @williamreay96]

Excited about my new preprint where we looked at genetic evidence of correlation and potential causal relationships between a panel of ~ 50 blood based biochemical markers and 10 psychiatric traits. @MurrayCairns @miffyjayne @HMRIAustralia @Uni_Newcastle. Short tweetorial 1/13

[Jackson Thorp @jacksonthorp]

Our paper modelling symptoms of anxiety, depression and neuroticism is now out in @NatureHumBehav

Link to paper: https://t.co/CwLnNTsOPx
Big thanks to @DerksEske @AdrianCamposG @zac_gerring @QIMRBerghofer

[Nature Human Behaviour @NatureHumBehav]

Symptom-level modelling unravels the shared genetic architecture of anxiety and depression https://t.co/UjcD5EiRwq From @jacksonthorp et al. @DerksEske

[Eiko Fried @EikoFried]

Exciting new work by Gaby Lunansky et al. on #network #resilience.

https://t.co/21g5DTPubq

[Abdel Abdellaoui @dr_appie]

Many psychiatric disorders and substance use outcomes share genetic effects. Controlling for genes associated with socio-economic outcomes changes the genetic relationships between these mental health outcomes. Our paper just out in @NatureHumBehav 🧬💸🧠

https://t.co/5XyugySs4k

[bioRxiv @biorxivpreprint]

A systematic analysis of genetically regulated differences in gene expression and the role of co-expression networks across 16 psychiatric disorders and substance use phenotypes https://t.co/zpjkunHtmm #bioRxiv

[QUT Library @qutlibrary]

Faculty of Health @RealHealthM - Brittany Mitchell
Exploring the genetic relationship between hearing impairment and Alzheimer’s disease. https://t.co/FA4WGgoOAS #BrittanyMitchell

[Jordan Smoller @jorsmo]

PLEIO: a method to map and interpret pleiotropic loci with GWAS summary statistics https://t.co/v3xLL6ed3e

[Brad Jermy @brad_jermy]

Happy Friday everyone! Our new pre-print is out! In it we explore how the genetic aetiology varies through systematic addition of components in a diagnosis of major depressive disorder (impairment, duration etc.). Welcome any thoughts!
https://t.co/5jFBom9oSO