Jai Padmakumar

Synthetic biologist ~ Co-founder at 1849 bio

[Connor Sweeney @_ConnorSweeney]

I’m thrilled to announce Baba, The American Healthcare Company.

Baba connects older adults and their families with dedicated advocates who can coordinate their care. Our advocates are nurses and social workers who have worked at the front lines of the healthcare system for decades, and who can get folks the resources they need.

This company was born of a family tragedy and has grown to support thousands of families across every corner of the country.

[Connor Sweeney @_ConnorSweeney]

Her brain went 6 hours without oxygen before they could operate.

On New Year's Eve in 2024, a 3mm-wide clump of cells wedged itself into an artery in my grandmother's brain.

She was in the passenger seat, next to her husband of 58 years, when she began to drool and lose motor function in her left arm.

She was having a stroke.

1/

[Askar Kleefeldt @askarkleefeldt]

👉 Read the full paper here: https://t.co/pS1PI71QCD

15/15

[Alexander J Triassi @AlexTriassi]

Really fun collaboration with @synlogic_tx! Super excited to see how the landing pad system that we built in the Voigt Lab (@Geneticdesigner) translates into the clinic in Synlogic’s future indications

[Jack Raines @Jack_Raines]

You've been speaking English your entire life

but did you know that the words you speak are all created from 26 individual letters?

Here are the 26 letters that you MUST know:

[mark belan | science illustrator + info designer @markabelan]

Visualizing the Biomass of Life 🦊🦀🐬🦎🦃🐓🦩🦆🌳☘️🍄🌼🌍 #biomass #infographic #dataviz #datavisualization #EarthDay22 #earthday #sciart #life #illustration #art #science #data

[Jai Padmakumar @jai_padmakumar]

This would be awesome in presentations

[Sibin @sibinmohan]

I’ve been using #AnnotatedEquations in my recent papers. I think it really adds to the readability and understanding of the math.

Here are some examples. It uses #tikz in #latex.

Let me know if you like it. Happy for any feedback. [GitHub link: next tweet]

#AcademicChatter

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[Sibin @sibinmohan]

I’ve been using #AnnotatedEquations in my recent papers. I think it really adds to the readability and understanding of the math.

Here are some examples. It uses #tikz in #latex.

Let me know if you like it. Happy for any feedback. [GitHub link: next tweet]

#AcademicChatter

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[Khosla Ventures @khoslaventures]

Here's to 2022! https://t.co/uBMXrRkiTg

[Elliot Hershberg @ElliotHershberg]

It really seems like the Tao of Biotechnology is to learn to repurpose and harness the power of biology rather than to try to impose your will on it with force. CRISPR vs. x-ray induced mutagenesis, immunotherapy vs. chemotherapy, etc.

[Jai Padmakumar @jai_padmakumar]

@biologistimo @Caroline_Bartma I literally store all polymerases on my bench for weeks and have never had a problem.

[Amee Kapadia @ameekapadia]

Wish biotech had more physically “cool” imagery associated with it like other frontier tech has. Assays and gels just don’t have the same visual effect as rockets do🤷‍♀️

[XKCD Comic @xkcdComic]

Sloped Border https://t.co/jNH4I2gtmp https://t.co/hjWrHK7Cus

[Dr Ellie Murray, ScD @EpiEllie]

If i were a billionaire mad scientist, i wouldn’t be wasting my money on going to mars, i’d be genetically engineering narwhal tusks into horse genomes so we can have unicorns.

[Howard Salis @hsalis]

NEW ALGORITHM: Announcing the CDS Calculator, a new approach to designing protein coding sequences for maximum expression control. Rules include removing/preventing: [1] bad/slow synonymous codons, [2] inhibitory mRNA structures in the N-term region, /1
https://t.co/0O94CEE02n

[Eric Topol @EricTopol]

Pretty damn impressive
Thanks Darren Lu @Reddit

[Cees Dekker @cees_dekker]

Today we released a preprint https://t.co/pm7lPCpyZm
where we take a step towards the next challenge:
building a nanopore single-molecule PROTEIN sequencer! 😳

Awesome experiments by postdoc Henry Brinkerhoff of our #CDlab, augmented with MD simulations of @aksimentievLab
1/x

[Emily Leproust @EmilyLeproust]

#SynBio is the answer! Engineered bacteria can chew through traditional plastics, and bio-plastics offer strong alternatives…#synthetic biology can close the plastics loop.

https://t.co/oeYIki56Rr

[WIRED Science @WIREDScience]

Mesobot looks like a giant AirPods case, but it's in fact a sophisticated machine that tracks animals making the most epic migration on Earth. https://t.co/3AgXfAVEQT

[Jai Padmakumar @jai_padmakumar]

So crazy cool! Using a microbe adapted to a non-native host and deploying it to combat Dengue. Huge props to everyone who worked on this @WMPglobal

[Ed Yong is not here @edyong209]

For a change, a feel-good story about a viral disease.

A decades-long effort to infuse mosquitoes with a virus-blocking microbe culminated in a trial where dengue incidence fell by 77% in one of the most dengue-prone cities around.

Just astonishing.

https://t.co/VfiAFUlnoi