Jack Bateman

Biology professor at Bowdoin College. Genetics, flies, chromosomes, weird science 🥰

[Wallace Marshall @WallaceUcsf]

Single cells can learn without a nervous system, but how? In our new preprint, Deepa Rajan and I describe a simple model for habituation in Stentor cells, based on mechanoreceptor internalization and recycling, and test it with quantitative experiments.

https://t.co/R9bFjmtGp9

[Berkley Gryder @Berkley_Gryder]

Our newest paper is out today in PNAS!
Small-molecule disruption of androgen receptor–dependent chromatin clusters https://t.co/Ao8XpKJykJ

[Philipp Maass @NucleomeHunter]

🚨Inter-chromosomal contacts (‘kissing chromosomes’) organize human genome topology along a spatial gradient of genome activity (62 Hi-C datasets). Check https://t.co/a5izMPo6C4, @NatureComms, @4DNucleome, @The3DGenome, @humangenomeorg, @netscisociety, @Emblebi, @MoGen_Grads

[Nature Reviews Molecular Cell Biology @NatRevMCB]

Now Online: Transcription regulation by biomolecular condensates https://t.co/sant8OQ92m

[Harmit S. Malik @HarmitMalik]

Structural duality enables a single protein to act as a toxin–antidote pair for meiotic drive | PNAS https://t.co/EvqCPMO14e
&
A meiotic driver hijacks an epigenetic reader to disrupt mitosis in noncarrier offspring | PNAS https://t.co/AzhZQa5JO2

2 amazing papers! 🤩

[eLife - the journal @eLife]

A lab handbook can help with the day-to-day challenges of running a lab and promote a positive culture. Check out these in-depth resources, including a template, to help you write your own. 3/n
https://t.co/AqUZeBgxvD

[Tineke Lenstra @tinekelenstra]

Check out our latest review on how cooperativity influences transcriptional bursting. Kudos to the first author Charis Fountas! https://t.co/TEXbncV4J7

[microscopic images. @microscopicture]

dehydrated tardigrade coming back to life after water being poured over it

[Lucas Farnung @LucasFarnung]

I have written a concise review on chromatin transcription as part of the @JMolBiol special issue on transcription elongation. Check it out!

https://t.co/3T5ESqSh0l

[Angelika Feldmann @angifeldmann]

How are promoter interactions coordinated during cell differentiation? In our first paper, we investigate the temporal relationship between genome folding, transcription and histone modifications during ESC differentiation. (1)

[Hernan Garcia @HernanGGarcia]

New preprint by @jzhao111, Nick Lammers, @yangjoonkim and Simon Alamos! Combining optogenetics, live imaging and theoretical modeling to biochemically dissect repressor action in living animals.

https://t.co/xNn5bFFAhn

[Prof. Nikolai Slavov @slavov_n]

Timescales in Cell Biology

[Rafael Galupa @rafaelgalupa]

Emerging links between phase separation and transcription factor haploinsufficiency: Trends in Genetics https://t.co/DJCfV4Gn7h by the one and only Reiner Veitia

[ChristinaProenzaColes @ProenzaColes]

Born in Jamaica to an enslaved mother in 1799, John Russwurm attended Bowdoin College & studied the Haitian Revolution. After graduation, he & Samuel Cornish founded the anti-slavery newspaper Freedom’s Journal in 1827. The paper had a national & international readership.

[Mustafa [email protected] @MustafaMir16]

1/n) Excited to share our new preprint: Using high-res live embryo imaging we show that transcription factor hubs are localized to new genes when specific DNA binding is perturbed. Hub interaction kinetics at these new sites determine factor occupancy: https://t.co/ZkNklKMgTV

[Molecular Cell @MolecularCell]

Online Now: Transcription dynamics and genome organization in the mammalian nucleus: Recent advances https://t.co/GoduvzDZIU

[Ferdinand Greiss @FeSchiessl]

Latest preprint on transplanting chromosomes into microfluidic biochips and rebooting the genome with cell-free gene expression. The deconstruction into a simple artificial system revealed fascinating DNA swelling dynamics with transcription. Enjoy!

https://t.co/SexMRWkn3Z

[Jack Bateman @jbateman01]

@JullienFlynn Love it! How do you get them out? Any trouble with food slipping out when you do?

[Skirmantas Kriaucionis @sk_kriaucionis]

Cost of having DNA methylation: DNA replication by DNA polymerase epsilon is a source of C to T mutations in CpGs, especially methylated ones. This expands our understanding of one of the most widespread endogenous mutational mechanisms. https://t.co/V42N3MDEGG

[Jack Bateman @jbateman01]

@oligopain Also, please change your password.