Jerome Burgi

[Jerome Burgi @jbuergi]

Our next story (very soon) will focus on the interaction between this enzyme and Pex5, the main receptor for peroxisomal import.

A lot more cool stuff to discover!

[Jerome Burgi @jbuergi]

The first part of a story about the unexpected oligomerisation of a yeast peroxisomal enzyme.
Great collaboration with @lill_pascal and @GatsogiannisLab.
Asymmetric horseshoe-like assembly of peroxisomal Yeast Oxalyl-CoA synthetase https://t.co/4oMHFyaetv

[Jerome Burgi @jbuergi]

Oxalyl-CoA synthetase being one of the most abundant protein found in peroxisomes, we propose that its oligomerisation helps import into peroxisomes under specific growth conditions.

[Avraham Z. Cooper, MD 🩺 @AvrahamCooperMD]

This incredible study showed that cells can use chemoattractant gradients to SOLVE MAZES 🤯

https://t.co/1jJxbGRAla

#MedTwitter

[Julien Y. Dutheil @jydutheil]

Another preprint from the lab! We built a structural atlas of protein compensatory substitutions: The structural determinants of intra-protein compensatory substitutions https://t.co/QSXrwdrup5

Work led by Shilpi Chaurasia. Here is what we did and found (thread)

[cryoEM Papers @cryoEM_Papers]

8 A structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex solved by cryo-EM and AI https://t.co/iAojXlHXSd

[Giannone Lab @GiannoneLab]

Please check out our recent study @NatureCellBio. Using single protein tracking and optical tweezers to show that actin elongation forces control actin regulator dynamics and functions at the leading edge of membrane protrusions during cell migration.
https://t.co/siXiWulGUu

[Jan Kosinski @jankosinski]

We combined #AlphaFold and #cryoEM to build a new model of the nuclear pore complex, the largest complex in the human cell!
The structure covered by the model is 15x bigger than the human ribosome and 2x bigger than old nuclear pore models. 1/7
Read how: https://t.co/mCLg0hEQFr

[cryoEM Papers @cryoEM_Papers]

Structure of the human ATM kinase and mechanism of Nbs1 binding https://t.co/kKFaYLkSL0

[VDG Lab @ EPFL @VDGLab]

Our work is out! We are happy to share how #Palmitoylation controls #SARSCoV2 (#Covid19) #membrane #Cholesterol organization, and promotes #infection
https://t.co/qAUZI2ddx4

[Claudia Millán @cheshireminima]

Since the publication of #AlphaFold2 and #RoseTTAFold and now that the tools and models have been made accessible, there has been an avalanche of attempts to solve old crystal structures. This thread covers tips from the #PhaserTeam for doing #MR with these models. (1/...)

[EMBL-EBI @emblebi]

Get your protein structure data all in one place using 3D-Beacons Network – a new #openaccess platform that collates and standardises data from #alphafoldDB, @PDBeurope, @SWISS_MODEL, @proteinEnsemble and more.
https://t.co/Q7d5hbLrvV

[Jerome Burgi @jbuergi]

Switzerland is still quite beautiful ;)

[Jerome Burgi @jbuergi]

Incredible... It's a game changer

[EMBL @embl]

EMBL and @DeepMind have partnered – a breakthrough for science.

Together, we're providing a treasure trove of protein structure predictions powered by #AlphaFold to herald a new era for #AI-enabled biology.

https://t.co/QSM55eB2Fk

[Prof. Akiko Iwasaki @VirusesImmunity]

This thread is about alpha-gal syndrome (AGS) - meat allergy induced by tick bites. I’ve been living with AGS for >2 yrs. I hope this info will help those who suffer from this illness without knowing the cause. Please help bring awareness to #AGS (1/n)

https://t.co/9aqo6pFT5o

[Protein Data Bank @PDBeurope]

There are 297 new #PDB entries this week, including this #cryoEM structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex (7b9s), solved to 3.4 A resolution and published in @ScienceAdvances. View all new entries at https://t.co/54E03LeH5m

[Jerome Burgi @jbuergi]

Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes https://t.co/RZK9mljkHG

[Bloom Lab @jbloom_lab]

In a new study, I identify and recover a deleted set of #SARSCoV2 sequences that provide additional information about viruses from the early Wuhan outbreak: https://t.co/1zdeiOQ0vo (1/n)