Apparently COVID has made a come back. TikTok is full of people complaining that they canât believe they are unwell with covid19.
This guy has a message that is fitting for the occasion.
Sending my support from Japan.
In Japan mask wearing is not mandatory, but many people see it as a choice that shows consideration for others and helps them feel safer.
I hope the world continues discussing a safe environment for everyone, including people living with #longcovid
đšđą A huge new paper was just released on the IgG4 class-switch that follows repeated mRNA COVID boosters.
As many of you know, weâve known for a long time that one of the issues created by routine mRNA boosters is the âclass switchâ to the creation of IgG4 antibodies, instead of the more beneficial IgG1 and IgG3.
Since at least early 2024, weâve known that both production of IgG4 was an issue with repeated doses of mRNA, and that it was not a concern seen with repeated doses of Novavax/Nuvaxovid: https://t.co/Giohxoytj8
Essentially, IgG1 is what you want the most of, it neutralizes viruses and is good at recruiting immune cells. IgG4 is what you donât want, and itâs fairly harmful, because it still recognizes the virus and binds to it, but it doesnât neutralize effectively and it recruits fewer immune cells to help. In short, this is what we call âimmune toleranceâ. Think of the way that allergy shots work, where repeated doses are given to create a level of immune tolerance so that your body stops reacting to the allergen. Thatâs obviously extremely bad for a virus, because it means your immune system stops responding and isnât able to properly clear the infection - something that is an even bigger deal for a virus like SARS-CoV-2 that causes persistence-based Long COVID.
However, that early research was only done with a few doses of mRNA. A couple weeks ago, we got recent research showing that this issue just keeps getting worse as folks get more mRNA boosters over time. This isnât really surprisingâŠbut itâs important to have the confirmation. The study follows a cohort that received 6 mRNA boosters, and the proportion of IgG4 rises all the way to 26.6% (!) of total antibodies after the 6th dose. For context: in general, IgG4 typically sits around 4%, and anything above 10% is considered a high proportion.
Not only is this switch harmful because it creates the aforementioned immune tolerance, but itâs also why you canât trust studies that do head-to-head comparisons of total antibody levels created by mRNA vs Novavax/Nuvaxovid if they donât disclose the antibody subtypes. Itâs true that mRNA often produces a higher level of antibodies overall, and within the brief window immediately following vaccination, but thatâs completely irrelevant if a large portion of them are just IgG4.
Importantly, for the first time, these authors were even able to tie the IgG4 switch to a tangible increase in breakthrough infections - a 1 standard deviation increase in IgG4 proportions raised infection risk by a statistically significant 83%. HR = 1.83 [95% CI= 1.07-3.17], p = 0.028.
Study link: https://t.co/HTIBpxRnDN
WHEN YOU REALIZE THE BABY BOOM WASN'T JUST SOLDIERS COMING HOME HORNY.
It was soldiers coming home to the GI Bill free college, 0% down home loans, low-interest business loans.
It was strong unions. Pensions. A house that cost 2 years of salary.
It was confidence that the future was actually going to be better than the present.
That's what produced a baby boom. Not romance. Security.
You want a higher birth rate now?
Give people a future where they know their kids will actually be okay.
That's the whole formula. It's not complicated. It's just expensive, and nobody in charge wants to pay for it twice.
Babe, remember:
The victim of narcissistic abuse is often the one whoâs visibly breaking down. Theyâre the one crying, reacting, and looking âcrazyâ because theyâve been pushed to their emotional limit.
Meanwhile, the abuser stays calm and composed, telling everyone, âSee? Look how crazy they are.â
Itâs strange how, in this generation, when victims finally speak about how they were hurt, theyâre often labeled as âtoxicâ or âdramaticâ. Werenât we the same people encouraging them to find their voice?
The irony is that when they stay quiet, theyâre told to speak up. But when they finally do, theyâre criticized for being inappropriate, pretentious, or simply told they should have kept it to themselves.
I really related to this.
Being Gen X is terrifying right now given the state of affairs in the world.
We donât have the time to save for another retirement if the markets get hit hard.
Our generation has lost 40-50% of their money 3 times since we started working.
@michael_hoerger@Csvich To paraphrase Freud, if youâre not crazy, then youâre crazy, because youâre living in a crazy world. Our anxiety and rage is a healthy reaction to this time of chaos and tragedy!
I am repeatedly astounded by the traumatic toll of NOT being seen, understood, and believed.
I want to remind you: YOUR pain, suffering, and loss is REAL even if people are minimizing it or trying to quantify it in relation to anotherâs pain.
I believe you.
I believe you.
I believe you. XO, Dr. Jen
@1dani__ Ugh. It's an apartment you pay to live in and should have a right to exist in 24/7 if you so wish - that is the contract. It's NOT an overnight shelter or night by night motel!
I donât care how âefficientâ the private sector is.
Some services should never be run as businesses.
Health care. Water. Electricity. Gas. Prisons.
If a company makes more money when people get sicker, stay locked up longer, or have no choice but to pay, thatâs a system built on conflicting interests.
Somehow, the American Dream has been downgraded into a luxury.
People arenât asking for mansions, private jets, or six-figure sports cars.
Theyâre asking for a life that used to be considered ordinary.
Being able to buy groceries without checking your bank balance first.
Paying rent without sacrificing half your monthly income.
Getting medical care without fearing the bill.
Having enough time and energy after work to enjoy dinner with the people you love.
These arenât extravagant expectations.
Theyâre the basics.
Yet todayâs economy treats those basics like theyâre privileges instead of the minimum people should be able to count on.
An answer to the loneliness crisis isn't telling people with long Covid & other disabilities to take more health risks. It's creating a society where people don't have to choose between protecting their health & participating in community in the first place
In 1973, a Stanford psychologist and colleagues feigned hallucinations to gain admission to psychiatric hospitals, but after entry their normal behavior was still interpreted as illness and they were refused dischargeâwhile only the other patients consistently recognized they were sane.
The second phase of the study was even more striking.
After the initial experiment, a psychiatric hospital challenged Rosenhan to send additional fake patients, confident its staff would be able to detect them. Rosenhan agreedâbut no pseudopatients were sent at all. Over the following weeks, the hospital evaluated 193 incoming patients and flagged 41 as potential impostors, with 19 considered suspicious by both a psychiatrist and another staff member.
The studyâs central conclusion was not that psychiatry lacked value, but that diagnosis at the time could be highly subjective. In the first phase, healthy volunteers who pretended to hear voices were admitted and, despite behaving normally afterward, continued to be viewed through the lens of illness. Even after their symptoms ceased, many struggled to be released and often had to accept diagnoses and treatment to secure discharge.
The second phase revealed the opposite problem: in reacting to the initial findings, clinicians became so cautious about deception that they began suspecting genuine patients of faking illnessâdespite no impostors being present.
The Rosenhan experiment remains one of the most influential and debated studies in psychiatry, continuing to shape discussions about diagnostic bias, labeling, and how mental illness is distinguished from normal behavior.
Yeah, people out here using CPNs and fake check stubs just to get a PLACE TO LIVE. Not to scam. Not to run off with somebodyâs money. Not because they waking up looking for a way to beat the system. But because the system been beating them for years.
How you want somebody to make 3ïžâŁx the rent, have a 700+ credit score, no collections, no charge offs, no evictions, perfect rental history, and six months worth of pay stubs just to get approved for a basic apartment? Yâall got people applying for apartments like they applying for a mortgage.
And letâs be real for a second. Can WE see YOUR credit, Mr. Landlord? Can we see if YOU got collections? Can we see if YOU never missed a payment? Can we see if YOU never had a rough patch? I bet we canât.
Life happens. People lose jobs. People get sick đ·. People go through divorces. Businesses fail. Emergencies happen. Folks get knocked down and have to figure it out. But some of these housing requirements treat people like they should be punished forever for one bad chapter. Thatâs the part that gets me.
A person can work every day, pay their bills, take care of their kids, stay out of trouble, and still get denied because of something sitting on a credit report from years ago.
Meanwhile rent keeps going up.
Deposits keep going up.
Application fees keep going up.
But wages? Not so much.
So yeah, some people start looking for loopholes. Not because theyâre criminals. Not because theyâre lazy. But because when every door đȘ gets slammed in your face, eventually people start looking for a window.
Everybody ainât asking for luxury. Everybody ainât asking for granite countertops and rooftop pools.
Some people just want a safe place to sleep and a stable place to raise their kids.
And if that sounds controversial to you, maybe the problem ainât the people trying to get housing. Maybe the problem is the system deciding who deserves it.
đŁïž I SAID WHAT I SAID.
The average rent in the U.S. just hit $2,000 a month.
The federal minimum wage net pay is $1,256 a month.
Let that math sink in.
Someone working full time still comes up $744 short of just paying rent.
Before food. Before utilities. Before gas. Before anything.
This isnât laziness. This isnât poor budgeting.
You cannot budget your way out of earning less than your rent costs.
The federal minimum wage hasnât changed since 2009. Rent has nearly doubled in that same time.
The system isnât broken by accident.
And until wages catch up, which could take decades, generating income outside of one hourly job isnât optional anymore.
Itâs survival.
~Casper Capital~