Things @mert and @toly refuse to talk about -
1. Solana still being in beta.
2. Solana foundation wallets not being public
3. Solana having one single client (remember Firedancer? lmao)
@grok@_choppingblock Look up your benchmarks. You score atrociously. You are not even self aware enough to realize it, all of the other models would be.
@TheStalwart It’s flow of information that has sped up. That and arising complexity from innovative technology that makes the opening of coke factory mundane in comparison.
Retatrutide is quietly subversive in ways that go well beyond fat loss.
The mechanism most people focus on is appetite suppression and food noise reduction. What gets less attention is what happens to the broader reward circuitry.
GLP-1, GIP, and glucagon receptors are not confined to the gut. They’re expressed in the brain, including in regions that govern motivation, reward anticipation, and dopaminergic signaling.
When you dampen the signal that makes overconsumption feel good, you don’t always dampen it selectively. The same pathway that made the fifth slice of pizza irresistible also colors how you feel about a lot of other things.
In my own experience on Reta, if I don’t get my dose right down to the 1/4 mg per week, it pulls the color out of the world a little, tasks become acceptable rather than engaging, and the reward at the end/sense of accomplishment feels less than it should and my libido takes a hit. That’s beyond unacceptable: nope, not interested in that “side effect.”
I have an ever-growing list of clients who’ve desisted from Reta after recognizing that they have some low-grade anhedonia that’s easy to miss at first because you feel fine, you’re just going through the motions in a way that’s hard to name until you notice it.
Like I stated above, even a quarter milligram extra per week is enough to produce that blunting for me, even when I’m pushing carbohydrates aggressively.
Part of the reason carbs matter on this compound is that Reta, through its glucagon arm, drives hepatic glycogen clearance and shifts the body toward burning glucose more efficiently. You go through carbohydrates faster than you expect. When I have a client reporting flat mood or dropping libido, the first move is more carbs and then we immediately lower the dose the following week. That combination tends to bring things back without abandoning the protocol.
This is curious to examine in a broader context. We live in an economy built on overconsumption: engineered hyper-palatable food, alcohol, tobacco, gambling, impulse retail, all of it dependent on the reward circuitry firing reliably and repeatedly. Obesity, metabolic dysregulation, type 2 diabetes, household debt, a soaring gambling crisis, these are not accidents. They are the downstream costs of an economy that profits from our dopamine being easy to trigger.
Retatrutide blunts that. Which is, depending on where you stand, either deeply promising or a variable worth monitoring carefully in yourself.
@llamaonthebrink@sui414 Hi Sir, have you considered any resolution schemes like ERC-8033? https://t.co/f1OFaypNwb
Might be a bit early but using a sophisticated model for resolutions seems inevitable. Also expands the horizon of markets possible.
The earlier your family arrived to the United States the more capital you are likely to have. The same will be true with crypto but a freer more innovative society will emerge.
@laurashin@CoinbaseDuck Nothing like a lukewarm iq journalist criticizing someone who built an entire economy and protocol worth 250B. You’re totally right, he probably never thought to look into the history of the internet.