🧵 THREAD: Redefining the sEV Proteome
1/6 🔬 Happy to share our work in @NatureCellBiol We’ve leveraged Protein Correlation Profiling to systematically define the reference proteomes of small Extracellular Vesicles and non-vesicular components. 🧬
🔗 https://t.co/hVPUdpcN0F
5/6 🚽 Clinical utility: We validated our DG-PCP workflow in serum and urine. Urine proved to be a superior, cleaner source for sEV-specific biomarkers, preserving parental cell molecular signatures for #PrecisionMedicine.
@jmunozpe and colleagues @CNIOStopCancer
and @biocrucesHRI use a method based on thermal stability to study how protein methylation regulates processes such as mRNA binding proteins and chromosome compaction
https://t.co/8VZXAX480p
Cristina Sayago, PhD student from my lab, just published her work on the analysis of protein methylation function with thermal stability analysis, check it out!👉
@CNIOStopCancer@biocrucesHRI@Ikerbasque@epic_xs
https://t.co/52rip36ZEh
Using time-resolved proteomics and metabolomics, the lab of @jmunozpe reveals mechanistic similarities and differences of two pharmacological approaches to stabilize naïve pluripotency @CNIOStopCancer@IRBBarcelona
https://t.co/gq2RCdNyD6
Dear all,
please retweet
We are opening a postdoctoral position in my group. The project will combine biochemistry and #cryoEM on CRISPR-Cas complexes. If you are interested contact me or [email protected]
Want to learn everything about mass spectrometry-based proteomics and metabolomics? Our BioMS course is held again in the week of the 26th of October. Everything is fully online, so no bars not to participate 🥳
https://t.co/SDqLV0snbx