Joan Smith

Principal Engineer at Google, AI and Infrastructure

[François Chollet @fchollet]

You can write a self-replicating physical program in just 45 tokens (RNA bases). That's small enough to emerge spontaneously via brute force recombination at scale.

[Joan Smith @joans]

@michellearning tokens, too

[Joan Smith @joans]

@michellearning @genentech @RecursionPharma @awscloud @nvidia Congratulations, Michelle! You're really building the future of scientific discovery

[Jason Sheltzer @JSheltzer]

I’m excited to share a new postdoctoral opportunity in my lab at Stanford to study the consequences of gene dosage alterations in iPS cells. Check out the posting below and shoot me an email if you’re interested -

[Jason Sheltzer @JSheltzer]

New from my lab on bioRxiv - we found an existing drug that appears to be safe in humans that selectively kills chemotherapy-resistant cancer cells.

[Jason Sheltzer @JSheltzer]

Thrilled to share our new paper describing the development and characterization of CDK11 inhibitors for cancer therapy. We also establish a new system that I think represents a huge leap forward in our ability to understand drug toxicity in a living organism.

[Joan Smith @joans]

I'm eager to get to know our new community -- please reach out and say hi!

[Joan Smith @joans]

I'm thrilled to share that my family and I are moving to Palo Alto. I'll be continuing my work at Google building out our AI infrastructure for maximal efficiency and speed.

[Joan Smith @joans]

It's an incredible time for the field and our company, and I am so excited to continue this work in-person with my brilliant colleagues.

And, pulling everything together, my husband Jason will be joining the faculty at Stanford, moving his cancer research lab from Yale.

[Jason Sheltzer @JSheltzer]

An interesting trend I found:

Among the top 10 national winners at the Intel/Westinghouse Science Fair from 1990 to 2002, 66% of them are now in academia.

Among the same group from 2003 to 2014, less than a third are academics.

[Jason Sheltzer @JSheltzer]

Check out our new study in @ScienceMagazine, where we take on a 100-year-old debate: what’s the role of aneuploidy in cancer?

We discovered that genetically removing extra chromosomes blocks cancer growth - a phenomenon we call “aneuploidy addiction”. https://t.co/K5ny7Ureph

[Jason Sheltzer @JSheltzer]

Proud to announce the launch of Meliora Therapeutics, a mechanism-focused drug development company, co-founded with @davidycli and @joans, with $11M in seed funding from @HOFCapital, @obviousvc, @Zhenfund, @villageglobal, and others.

https://t.co/zgZ5whecJI

[Jason Sheltzer @JSheltzer]

Welcome Tavi Glenn Sheltzer-Smith! Born on 4/21/22. 8 pounds 3 ounces, 21 inches long. Mother and baby are doing great!

[taber @cakesandcourage]

a popular myth is that people who are Very Computer have computers that work. nothing could be further from the truth. the Very Computer are capable of generating much more novel and fascinating ways to make computers not fucking work and exercise this capability wantonly

[Jason Sheltzer @JSheltzer]

New paper from @joans and me! A pan-cancer, cross-platform analysis identifies >100,000 genomic biomarkers for cancer outcomes. Plus, a website to explore the data (https://t.co/20fFzSgSEu) and a (controversial?) discussion of “cause” vs. “correlation” in cancer genome analysis.

[Jason Sheltzer @JSheltzer]

I’m excited to share that I’ll be joining the Yale School of Medicine as an assistant professor! My lab will be moving from CSHL to Yale this summer. And we’re hiring! If you’re interested in working on cancer genomics, chromosome engineering, or drug targeting, drop me a line.

[Joan Smith @joans]

This is a great team of smart and kind people that does super cool, meaningful work.

[Sachin Agarwal @agarwal]

Can’t wait for @wirecutter to tell me which vaccine to take.

[KizzyPhD @KizzyPhD]

Pfizer’s Covid-19 Vaccine Proves 90% Effective in Latest Trials
https://t.co/goEvxJaZDq

SCIENCE WINS!!! This is GREAT news for mRNA technology, AWESOME for the stabilized prefusion spike antigen.

I am in tears.

[Jason Sheltzer @JSheltzer]

same idea