Um enormรญssimo texto. Vale a pena ler e, acima de tudo, vale a pena agir no sentido do que รฉ dito no texto. Estamos sentados sobre um barril de pรณlvora e nรฃo vale a pena assobiar para o lado.
@BradSpellberg I appreciate your concerns with methodology and possible harm. Personally, I favour guidelines providing expert opinion for uncertain relevant points if properly disclosed, but I understood you point and maybe I donโt grasp the true impact of such in a system like yours. Thank U
@ABsteward@BradSpellberg@MartenHawkins@zacroBID@PulmCrit PHANTASi had only 4% patients in shock, ~100, and global mortality of 8% vs estimated of 40%. Probably lots of non severe patients included and time to hospital ~20 min. not the ideal data for the subject in hand, donโt you agree? Also couldnโt find specific shock group result
@BradSpellberg@MartenHawkins@ABsteward@zacroBID@PulmCrit I would agree on sepsis, not septic shock. What is the evidence that made irrelevant the time to abx in a septic shock patient? Enlighten me please, Dr Spellberg. I am a big fan of your work and cite you plenty, but couldnโt disagree more on this,neither by data nor experience.
@BradSpellberg@MartenHawkins@ABsteward@zacroBID@PulmCrit I believe that there is more than enough evidence to support that time to antibiotics (and source control) matters in patient already in shock. Do you wish proof that a shocked patient in an ambulance = shocked patient in an hospital? We are just fighting ghosts now.
@BradSpellberg@MartenHawkins@ABsteward@zacroBID@PulmCrit The โexpertsโ part shows the line of fair criticism is long gone. Much to criticize but strength of recs/evidence is well stated. Good Abx pre-hosp is hard but if achieved makes a diference. or can you do evidence backed statement that time to abx is irrelevant in septic shock?
@ABsteward@AliSMV7 In most european countries, a doctor. Abx can be protocolized according to regional microbiologic data and adjusted later if special considerations arrise. Cultures are >50% negative, does it justify delaying abx in a very small very sick group of patients? Deescalate without it
@MartenHawkins@ABsteward@zacroBID@BradSpellberg@PulmCrit All this whining from grown up docs about suggestion of pre-hospital antibiotics in patients with highly probable septic shock and predictable long time transport to hospital is just ambarrasing. Did I miss the memo saying time became irrelevant and stopping abx was impossible?
@DrJMarine@BradSpellberg As a typical cardiologist, you have your head so up your ass that you canโt understand other people reality even when you try. Your comments are appaling and clearly from someone who has no idea about how things were in those dreadful days. You are just embarrassing yourself.
Critical closing pressure - how it should guide personalised care
If CCP is a threshold (not a pressure), the clinical aim is simple:
๐ keep arterioles open
๐ preserve flow continuity from pump โ tissue
Not chase MAP or SVR in isolation.
https://t.co/BqDSedyClz
@ross_prager As still in shock after thrombolysis, did you repeat angioCT? Checked for refractory thrombus needing thrombectomy?
Seen a few of these and all had those and improved fast after PT.
What do you think about before NE as vasopressor due to less pulmonary vasoconstriction?
Movember starts today!
This month isย all about raising awareness of menโs health, especially prostate cancer, testicular cancer, mental health, and suicide prevention. โค๏ธโ๐ฉน
Early detection saves lives! In the EU, weโre taking action through โฌ๏ธ
Three years of resistance. Three years of gratitude. Three years of absolute heroism of Ukrainians. I am proud of Ukraine! I thank everyone who defends and supports it. Everyone who works for Ukraine. And may the memory of all those who gave their lives for our state and people be eternal. ๐บ๐ฆ๐บ๐ฆ๐บ๐ฆ
#SupportUkraine